| HER2 Amplification in Tumors Activates PI3K/Akt Signaling Independent of HER3 A Ruiz-Saenz, C Dreyer, MR Campbell, V Steri, N Gulizia, MM Moasser Cancer research 78 (13), 3645-3658, 2018 | 106 | 2018 |
| INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells L Andrés-Delgado, OM Antón, F Bartolini, A Ruiz-Sáenz, I Correas, ... Journal of Cell Biology 198 (6), 1025-1037, 2012 | 85 | 2012 |
| MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration JF Aranda, N Reglero-Real, L Kremer, B Marcos-Ramiro, A Ruiz-Sáenz, ... Molecular biology of the cell 22 (8), 1252-1262, 2011 | 59 | 2011 |
| A dimerization function in the intrinsically disordered N-terminal region of Src DS Spassov, A Ruiz-Saenz, A Piple, MM Moasser Cell reports 25 (2), 449-463. e4, 2018 | 46 | 2018 |
| MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression JF Aranda, N Reglero-Real, B Marcos-Ramiro, A Ruiz-Sáenz, ... Molecular biology of the cell 24 (4), 483-494, 2013 | 44 | 2013 |
| Protein 4.1 R regulates cell migration and IQGAP1 recruitment to the leading edge A Ruiz-Sáenz, L Kremer, MA Alonso, J Millán, I Correas Journal of cell science 124 (15), 2529-2538, 2011 | 34 | 2011 |
| Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities JP Coppé, M Mori, B Pan, C Yau, DM Wolf, A Ruiz-Saenz, D Brunen, ... Nature cell biology 21 (6), 778-790, 2019 | 30 | 2019 |
| Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum A Ruiz-Saenz, M Sandhu, Y Carrasco, RL Maglathlin, J Taunton, ... Oncogene 34 (41), 5288-5294, 2015 | 30 | 2015 |
| Protein 4.1 R binds to CLASP2 and regulates dynamics, organization and attachment of microtubules to the cell cortex A Ruiz-Saenz, J van Haren, CL Sayas, L Rangel, J Demmers, J Millan, ... Journal of cell science 126 (20), 4589-4601, 2013 | 21 | 2013 |
| Targeting of HER/ErbB family proteins using broad spectrum Sec61 inhibitors coibamide A and apratoxin A S Kazemi, S Kawaguchi, CE Badr, DR Mattos, A Ruiz-Saenz, JD Serrill, ... Biochemical pharmacology 183, 114317, 2021 | 17 | 2021 |
| Effective treatment of HER2-amplified breast cancer by targeting HER3 and β1 integrin MR Campbell, H Zhang, S Ziaee, A Ruiz-Saenz, N Gulizia, J Oeffinger, ... Breast cancer research and treatment 155, 431-440, 2016 | 17 | 2016 |
| A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors A Ruiz-Saenz, CE Atreya, C Wang, B Pan, CA Dreyer, D Brunen, ... Nature cancer 4 (2), 240-256, 2023 | 16 | 2023 |
| Targeting HER2 by combination therapies A Ruiz-Saenz, MM Moasser Journal of clinical oncology: official journal of the American Society of …, 2018 | 15 | 2018 |
| Alternative polyadenylation in a family of paralogous EPB41 genes generates protein 4.1 diversity L Rangel, E Lospitao, A Ruiz-Sáenz, MA Alonso, I Correas RNA biology 14 (2), 236-244, 2017 | 11 | 2017 |
| Extensive conformational and physical plasticity protects HER2-HER3 tumorigenic signaling MR Campbell, A Ruiz-Saenz, Y Zhang, E Peterson, V Steri, J Oeffinger, ... Cell reports 38 (5), 2022 | 10 | 2022 |
| Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers MR Campbell, A Ruiz-Saenz, E Peterson, C Agnew, P Ayaz, S Garfinkle, ... Cell reports 38 (5), 2022 | 9 | 2022 |
| Proteomic analysis of Src family kinase phosphorylation states in cancer cells suggests deregulation of the unique domain A Ruiz-Saenz, F Zahedi, E Peterson, A Yoo, CA Dreyer, DS Spassov, ... Molecular Cancer Research 19 (6), 957-967, 2021 | 9 | 2021 |
| Chemical probing of HER2-amplified cancer cells identifies TORC2 as a particularly effective secondary target for combination with lapatinib DN Amin, A Ruiz-Saenz, N Gulizia, MM Moasser Oncotarget 6 (38), 41123, 2015 | 3 | 2015 |
| Tumor glycosylation impacts the efficacy of HER2 targeting therapies A Ruiz-Saenz, R Vincken, D Wolf, V Steri, L Veer, J Martens, ... Cancer Research 84 (6_Supplement), 2014-2014, 2024 | | 2024 |
| A co-culture model system to quantify antibody-dependent cellular cytotoxicity in human breast cancer cells using an engineered natural killer cell line R Vincken, A Ruiz-Saenz STAR protocols 4 (2), 102224, 2023 | | 2023 |
