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Aymelt Itzen
Aymelt Itzen
Professor of Biochemistry, University Medical Center Hamburg-Eppendorf (UKE)
Dirección de correo verificada de uke.de - Página principal
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The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b
MP Müller, H Peters, J Blümer, W Blankenfeldt, RS Goody, A Itzen
Science 329 (5994), 946-949, 2010
4372010
RabGEFs are a major determinant for specific Rab membrane targeting
J Blümer, J Rey, L Dehmelt, T Mazel, YW Wu, P Bastiaens, RS Goody, ...
Journal of Cell Biology 200 (3), 287-300, 2013
2302013
Rab GTPase–Myo5B complexes control membrane recycling and epithelial polarization
JT Roland, DM Bryant, A Datta, A Itzen, KE Mostov, JR Goldenring
Proceedings of the National Academy of Sciences 108 (7), 2789-2794, 2011
2162011
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity
S Schoebel, LK Oesterlin, W Blankenfeldt, RS Goody, A Itzen
Molecular cell 36 (6), 1060-1072, 2009
1972009
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1842015
Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins
PR Goody, K Heller, LK Oesterlin, MP Müller, A Itzen, RS Goody
The EMBO journal 31 (7), 1774-1784, 2012
1332012
Nucleotide exchange via local protein unfolding—structure of Rab8 in complex with MSS4
A Itzen, O Pylypenko, RS Goody, K Alexandrov, A Rak
The EMBO journal 25 (7), 1445-1455, 2006
1202006
GTPases involved in vesicular trafficking: structures and mechanisms
A Itzen, RS Goody
Seminars in cell & developmental biology 22 (1), 48-56, 2011
1192011
A structural basis for Lowe syndrome caused by mutations in the Rab‐binding domain of OCRL1
X Hou, N Hagemann, S Schoebel, W Blankenfeldt, RS Goody, ...
The EMBO journal 30 (8), 1659-1670, 2011
1152011
Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection
E Rothmeier, G Pfaffinger, C Hoffmann, CF Harrison, H Grabmayr, ...
PLoS pathogens 9 (9), e1003598, 2013
1142013
High‐affinity binding of phosphatidylinositol 4‐phosphate by Legionella pneumophila DrrA
S Schoebel, W Blankenfeldt, RS Goody, A Itzen
EMBO reports 11 (8), 598-604, 2010
1082010
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner
G Yin, TL Da Fonseca, SE Eisbach, AM Anduaga, C Breda, ML Orcellet, ...
Neurobiology of disease 70, 149-161, 2014
1032014
Direct Targeting of Rab‐GTPase–Effector Interactions
J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann
Angewandte Chemie International Edition 53 (9), 2498-2503, 2014
1032014
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting
F Li, L Yi, L Zhao, A Itzen, RS Goody, YW Wu
Proceedings of the National Academy of Sciences 111 (7), 2572-2577, 2014
982014
Protein LidA from Legionella is a rab GTPase supereffector
S Schoebel, AL Cichy, RS Goody, A Itzen
Proceedings of the National Academy of Sciences 108 (44), 17945-17950, 2011
882011
Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor
LK Oesterlin, RS Goody, A Itzen
Proceedings of the National Academy of Sciences 109 (15), 5621-5626, 2012
792012
Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB
E Mihai Gazdag, A Streller, I Haneburger, H Hilbi, IR Vetter, RS Goody, ...
EMBO reports 14 (2), 199-205, 2013
772013
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation
L Langemeyer, R Nunes Bastos, Y Cai, A Itzen, KM Reinisch, FA Barr
Elife 3, e01623, 2014
752014
Adenylylation: renaissance of a forgotten post-translational modification
A Itzen, W Blankenfeldt, RS Goody
Trends in biochemical sciences 36 (4), 221-228, 2011
712011
Catalytic mechanism of a mammalian Rab· RabGAP complex in atomic detail
K Gavriljuk, EM Gazdag, A Itzen, C Kötting, RS Goody, K Gerwert
Proceedings of the National Academy of Sciences 109 (52), 21348-21353, 2012
692012
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