| Monoclonal TCR-redirected tumor cell killing N Liddy, G Bossi, KJ Adams, A Lissina, TM Mahon, NJ Hassan, J Gavarret, ... Nature medicine 18 (6), 980-987, 2012 | 1003 | 2012 |
| Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection DA Price, PJR Goulder, P Klenerman, AK Sewell, PJ Easterbrook, ... Proceedings of the National Academy of Sciences 94 (5), 1890-1895, 1997 | 907 | 1997 |
| Why must T cells be cross-reactive? AK Sewell Nature Reviews Immunology 12 (9), 669-677, 2012 | 559 | 2012 |
| A single autoimmune T cell receptor recognizes more than a million different peptides L Wooldridge, J Ekeruche-Makinde, H Van Den Berg, A Skowera, ... Journal of Biological Chemistry 287 (2), 1168-1177, 2012 | 497 | 2012 |
| Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes A Oxenius, DA Price, PJ Easterbrook, CA O'Callaghan, AD Kelleher, ... Proceedings of the National Academy of Sciences 97 (7), 3382-3387, 2000 | 493 | 2000 |
| Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses DA Price, JM Brenchley, LE Ruff, MR Betts, BJ Hill, M Roederer, RA Koup, ... The Journal of experimental medicine 202 (10), 1349-1361, 2005 | 462 | 2005 |
| CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope A Skowera, RJ Ellis, R Varela-Calviño, S Arif, GC Huang, C Van-Krinks, ... The Journal of clinical investigation 118 (10), 3390-3402, 2008 | 454 | 2008 |
| VDJdb: a curated database of T-cell receptor sequences with known antigen specificity M Shugay, DV Bagaev, IV Zvyagin, RM Vroomans, JC Crawford, G Dolton, ... Nucleic acids research 46 (D1), D419-D427, 2018 | 414 | 2018 |
| VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium DV Bagaev, RMA Vroomans, J Samir, U Stervbo, C Rius, G Dolton, ... Nucleic Acids Research 48 (D1), D1057-D1062, 2020 | 312 | 2020 |
| Structural and kinetic basis for heightened immunogenicity of T cell vaccines JL Chen, G Stewart-Jones, G Bossi, NM Lissin, L Wooldridge, EML Choi, ... The Journal of experimental medicine 201 (8), 1243-1255, 2005 | 308 | 2005 |
| Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor A Varela-Rohena, PE Molloy, SM Dunn, Y Li, MM Suhoski, RG Carroll, ... Nature medicine 14 (12), 1390-1395, 2008 | 304 | 2008 |
| Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA A Leslie, D Kavanagh, I Honeyborne, K Pfafferott, C Edwards, T Pillay, ... The Journal of experimental medicine 201 (6), 891-902, 2005 | 287 | 2005 |
| Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties B Laugel, HA van den Berg, E Gostick, DK Cole, L Wooldridge, J Boulter, ... Journal of Biological Chemistry 282 (33), 23799-23810, 2007 | 274 | 2007 |
| Human TCR-binding affinity is governed by MHC class restriction DK Cole, NJ Pumphrey, JM Boulter, M Sami, JI Bell, E Gostick, DA Price, ... The Journal of Immunology 178 (9), 5727-5734, 2007 | 267 | 2007 |
| The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is … RE Hewitt, A Lissina, AE Green, ES Slay, DA Price, AK Sewell Clinical & Experimental Immunology 139 (1), 101-111, 2005 | 267 | 2005 |
| Tricks with tetramers: how to get the most from multimeric peptide–MHC L Wooldridge, A Lissina, DK Cole, HA Van Den Berg, DA Price, AK Sewell Immunology 126 (2), 147-164, 2009 | 239 | 2009 |
| Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 MD Crowther, G Dolton, M Legut, ME Caillaud, A Lloyd, M Attaf, ... Nature immunology 21 (2), 178-185, 2020 | 231 | 2020 |
| T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009 | 230 | 2009 |
| Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination SV Pageon, T Tabarin, Y Yamamoto, Y Ma, PR Nicovich, JS Bridgeman, ... Proceedings of the National Academy of Sciences 113 (37), E5454-E5463, 2016 | 229 | 2016 |
| Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies PM Maciocia, PA Wawrzyniecka, B Philip, I Ricciardelli, AU Akarca, ... Nature medicine 23 (12), 1416-1423, 2017 | 228 | 2017 |
David ColeHonorary Professor, Cardiff UniversityVerified email at cf.ac.uk
