Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose? MR Alison, NJ Guppy, SML Lim, LJ Nicholson The Journal of pathology 222 (4), 335-344, 2010 | 161 | 2010 |
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response S Nagarajan, SV Rao, J Sutton, D Cheeseman, S Dunn, EK Papachristou, ... Nature genetics 52 (2), 187-197, 2020 | 136 | 2020 |
EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen S Scheipl, M Barnard, L Cottone, M Jorgensen, DH Drewry, WJ Zuercher, ... The Journal of pathology 239 (3), 320-334, 2016 | 82 | 2016 |
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance LR Garcia, T Tenev, R Newman, RO Haich, G Liccardi, SW John, ... Nature Communications 12 (1), 3364, 2021 | 51 | 2021 |
C-terminal tensin-like gene functions as an oncogene and promotes cell motility in pancreatic cancer S Al-Ghamdi, J Cachat, A Albasri, M Ahmed, D Jackson, A Zaitoun, ... Pancreas 42 (1), 135-140, 2013 | 50 | 2013 |
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells KK Kolluri, C Alifrangis, N Kumar, Y Ishii, S Price, M Michaut, S Williams, ... Elife 7, e30224, 2018 | 34 | 2018 |
Validation of immune cell modules in multicellular transcriptomic data G Pollara, MJ Murray, JM Heather, R Byng-Maddick, N Guppy, M Ellis, ... PloS one 12 (1), e0169271, 2017 | 30 | 2017 |
The impact of diet‐induced weight loss on biomarkers for colorectal cancer: an exploratory study (INTERCEPT) RJ Beeken, H Croker, M Heinrich, A Obichere, N Finer, N Murphy, ... Obesity 25, S95-S101, 2017 | 29 | 2017 |
Cellular pathways to β‐cell replacement TG Fellous, NJ Guppy, M Brittan, MR Alison Diabetes/metabolism research and reviews 23 (2), 87-99, 2007 | 29 | 2007 |
Trefoil factor family peptides in normal and diseased human pancreas NJ Guppy, ME El-Bahrawy, HM Kocher, K Fritsch, YA Qureshi, R Poulsom, ... Pancreas 41 (6), 888-896, 2012 | 27 | 2012 |
RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma HG Smith, K Jamal, JHS Dayal, T Tenev, J Kyula‐Currie, N Guppy, ... EMBO Molecular Medicine 12 (6), e10979, 2020 | 23 | 2020 |
Monocyte-macrophage activation is associated with nonalcoholic fatty liver disease and liver fibrosis in HIV monoinfection independently of the gut microbiome and bacterial … JB Maurice, L Garvey, EA Tsochatzis, M Wiltshire, G Cooke, N Guppy, ... Aids 33 (5), 805-814, 2019 | 22 | 2019 |
Tumor necrosis factor (TNF) bioactivity at the site of an acute cell-mediated immune response is preserved in rheumatoid arthritis patients responding to anti-TNF therapy R Byng-Maddick, CT Turner, G Pollara, M Ellis, NJ Guppy, LCK Bell, ... Frontiers in Immunology 8, 932, 2017 | 18 | 2017 |
Unmasking the immune microecology of ductal carcinoma in situ with deep learning PL Narayanan, SEA Raza, AH Hall, JR Marks, L King, RB West, ... NPJ breast cancer 7 (1), 19, 2021 | 17 | 2021 |
Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse FK Turrell, R Orha, NJ Guppy, A Gillespie, M Guelbert, C Starling, ... Nature Cancer 4 (4), 468-484, 2023 | 15 | 2023 |
BRCA1/MAD2L1 deficiency disrupts the spindle assembly checkpoint to confer vinorelbine resistance in mesothelioma S Busacca, L O'Regan, A Singh, AJ Sharkey, AG Dawson, J Dzialo, ... Molecular cancer therapeutics 20 (2), 379-388, 2021 | 15 | 2021 |
Quantitative assessment and prognostic associations of the immune landscape in ovarian clear cell carcinoma S Khalique, S Nash, D Mansfield, J Wampfler, A Attygale, K Vroobel, ... Cancers 13 (15), 3854, 2021 | 13 | 2021 |
Retrospective response analysis of BAP1 expression to predict the clinical activity of systemic cytotoxic chemotherapy in mesothelioma N Kumar, D Alrifai, KK Kolluri, EK Sage, Y Ishii, N Guppy, E Borg, ... Lung Cancer 127, 164-166, 2019 | 13 | 2019 |
Rapid and complete paraffin removal from human tissue sections delivers enhanced Raman spectroscopic and histopathological analysis R Gaifulina, DJ Caruana, D Oukrif, NJ Guppy, S Culley, R Brown, I Bell, ... Analyst 145 (4), 1499-1510, 2020 | 12 | 2020 |
Integrin α2β1 expression regulates Matrix Metalloproteinase-1-dependent bronchial epithelial repair in pulmonary tuberculosis S Brilha, DLW Chong, AA Khawaja, CWM Ong, NJ Guppy, JC Porter, ... Frontiers in Immunology 9, 359701, 2018 | 12 | 2018 |