| Supercomplex assembly determines electron flux in the mitochondrial electron transport chain E Lapuente-Brun, R Moreno-Loshuertos, R Acín-Pérez, A Latorre-Pellicer, ... Science 340 (6140), 1567-1570, 2013 | 880 | 2013 |
| Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals PM Quirós, MA Prado, N Zamboni, D D’Amico, RW Williams, D Finley, ... Journal of Cell Biology 216 (7), 2027-2045, 2017 | 668 | 2017 |
| Mitonuclear communication in homeostasis and stress PM Quirós, A Mottis, J Auwerx Nature reviews Molecular cell biology 17 (4), 213-226, 2016 | 660 | 2016 |
| New roles for mitochondrial proteases in health, ageing and disease PM Quirós, T Langer, C López-Otín Nature reviews Molecular cell biology 16 (6), 345-359, 2015 | 516 | 2015 |
| Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ... Cell reports 10 (10), 1681-1691, 2015 | 482 | 2015 |
| Splicing-directed therapy in a new mouse model of human accelerated aging FG Osorio, CL Navarro, J Cadiñanos, IC López-Mejía, PM Quirós, ... Science translational medicine 3 (106), 106ra107-106ra107, 2011 | 444 | 2011 |
| Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice C Bárcena, R Valdés-Mas, P Mayoral, C Garabaya, S Durand, ... Nature medicine 25 (8), 1234-1242, 2019 | 407 | 2019 |
| Two conserved histone demethylases regulate mitochondrial stress-induced longevity C Merkwirth, V Jovaisaite, J Durieux, O Matilainen, SD Jordan, PM Quiros, ... Cell 165 (5), 1209-1223, 2016 | 323 | 2016 |
| Analysis of mtDNA/nDNA ratio in mice PM Quiros, A Goyal, P Jha, J Auwerx Current protocols in mouse biology 7 (1), 47-54, 2017 | 307 | 2017 |
| Mitochondria and epigenetics–crosstalk in homeostasis and stress O Matilainen, PM Quirós, J Auwerx Trends in cell biology 27 (6), 453-463, 2017 | 295 | 2017 |
| Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice PM Quirós, AJ Ramsay, D Sala, E Fernández‐Vizarra, F Rodríguez, ... The EMBO journal 31 (9), 2117-2133, 2012 | 270 | 2012 |
| ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity PM Quirós, Y Espanol, R Acín-Pérez, F Rodríguez, C Barcena, ... Cell reports 8 (2), 542-556, 2014 | 199 | 2014 |
| Premature aging in mice activates a systemic metabolic response involving autophagy induction G Marino, AP Ugalde, N Salvador-Montoliu, I Varela, PM Quiros, ... Human molecular genetics 17 (14), 2196-2211, 2008 | 182 | 2008 |
| Mitohormesis, an antiaging paradigm C Bárcena, P Mayoral, PM Quirós International review of cell and molecular Biology 340, 35-77, 2018 | 155 | 2018 |
| Methionine restriction extends lifespan in progeroid mice and alters lipid and bile acid metabolism C Bárcena, PM Quirós, S Durand, P Mayoral, F Rodríguez, XM Caravia, ... Cell reports 24 (9), 2392-2403, 2018 | 149 | 2018 |
| Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria A Korwitz, C Merkwirth, R Richter-Dennerlein, SE Tröder, HG Sprenger, ... Journal of Cell Biology 212 (2), 157-166, 2016 | 133 | 2016 |
| Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis SP Kar, PM Quiros, M Gu, T Jiang, J Mitchell, R Langdon, V Iyer, ... Nature Genetics 54 (8), 1155-1166, 2022 | 129 | 2022 |
| OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury X Xiao, Y Hu, PM Quirós, Q Wei, C López-Otín, Z Dong American Journal of Physiology-Renal Physiology 306 (11), F1318-F1326, 2014 | 119 | 2014 |
| Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells A Vazquez-Martin, L Vellon, PM Quiros, S Cufi, E Ruiz de Galarreta, ... Cell cycle 11 (5), 974-989, 2012 | 105 | 2012 |
| Proteomic profiling of adipose tissue from Zmpste24−/− mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing JR Peinado, PM Quiros, MR Pulido, G Marino, ML Martínez-Chantar, ... Molecular & Cellular Proteomics 10 (11), 2011 | 77 | 2011 |
Johan AuwerxProfessor at the EPFLVerified email at epfl.ch
