Thierry Chardès
Thierry Chardès
Research Director, DR1 CNRS, PhD, PharmD
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A peptide mimetic of an anti-CD4 monoclonal antibody by rational design
F Casset, F Roux, P Mouchet, C Bes, T Chardes, C Granier, JC Mani, ...
Biochemical and biophysical research communications 307 (1), 198-205, 2003
4962003
Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.
T Chardes, D Buzoni-Gatel, A Lepage, F Bernard, D Bout
The Journal of Immunology 153 (10), 4596-4603, 1994
1441994
A neuronal isoform of nitric oxide synthase expressed in pancreatic β-cells controls insulin secretion
AD Lajoix, H Reggio, T Chardès, S Péraldi-Roux, F Tribillac, M Roye, ...
Diabetes 50 (6), 1311-1323, 2001
1312001
Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens.
T Chardes, I Bourguin, MN Mevelec, JF Dubremetz, D Bout
Infection and Immunity 58 (5), 1240-1246, 1990
1301990
Anti-HER2 vaccines: new prospects for breast cancer therapy
MZ Ladjemi, W Jacot, T Chardès, A Pèlegrin, I Navarro-Teulon
Cancer Immunology, Immunotherapy 59 (9), 1295-1312, 2010
1272010
The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases
T Chardès, N Chapal, D Bresson, C Bès, V Giudicelli, MP Lefranc, ...
Immunogenetics 54 (3), 141-157, 2002
1032002
Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies
MN Mevelec, T Chardès, O Mercereau-Puijalon, I Bourguin, A Achbarou, ...
Molecular and biochemical parasitology 56 (2), 227-238, 1992
931992
Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding
D Laune, F Molina, G Ferrières, S Villard, C Bès, F Rieunier, T Chardès, ...
Journal of immunological methods 267 (1), 53-70, 2002
922002
Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice.
T Chardes, F Velge-Roussel, P Mevelec, MN Mevelec, D Buzoni-Gatel, ...
Immunology 78 (3), 421, 1993
891993
Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice.
I Bourguin, T Chardès, D Bout
Infection and immunity 61 (5), 2082-2088, 1993
811993
In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of …
C Larbouret, N Gaborit, T Chardès, M Coelho, E Campigna, ...
Neoplasia 14 (2), 121-130, 2012
762012
Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells
C Monnet, D Laune, J Laroche-Traineau, M Biard-Piechaczyk, L Briant, ...
Journal of Biological Chemistry 274 (6), 3789-3796, 1999
731999
Protection against Chlamydia psittaci in mice conferred by Lyt-2+ T cells.
D Buzoni-Gatel, L Guilloteau, F Bernard, S Bernard, T Chardes, A Rocca
Immunology 77 (2), 284, 1992
671992
Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy
W Leconet, C Larbouret, T Chardès, G Thomas, M Neiveyans, M Busson, ...
Oncogene 33 (47), 5405-5414, 2014
632014
Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1
F Velge-Roussel, T Chardes, P Mévélec, M Brillard, J Hoebeke, D Bout
Molecular and biochemical parasitology 66 (1), 31-38, 1994
601994
Time-resolved Fluorescence Resonance Energy Transfer (TR-FRET) to Analyze the Disruption of EGFR/HER2 Dimers A NEW METHOD TO EVALUATE THE EFFICIENCY OF TARGETED THERAPY USING …
N Gaborit, C Larbouret, J Vallaghe, F Peyrusson, C Bascoul-Mollevi, ...
Journal of Biological Chemistry 286 (13), 11337-11345, 2011
592011
Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases
D Bresson, M Cerutti, G Devauchelle, M Pugnière, F Roquet, C Bès, ...
Journal of Biological Chemistry 278 (11), 9560-9569, 2003
512003
Efficient amplification and direct sequencing of mouse variable regions from any immunoglobulin gene family
T Chardès, S Villard, G Ferrières, M Piechaczyk, M Cerutti, G Devauchelle, ...
FEBS letters 452 (3), 386-394, 1999
491999
Production and characterization of monoclonal antibodies against human thyroglobulin
M PIECHACZYK, T CHARDES, MC COT, B PAU, JM BASTIDE
Hybridoma 4 (4), 361-367, 1985
471985
Amplification of the secretory IgA response to Toxoplasma gondii using cholera toxin
I Bourguin, T Chardes, MN Mevelec, JP Woodman, D Bout
FEMS microbiology letters 81 (3), 265-271, 1991
461991
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