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Thierry Chardès
Thierry Chardès
Research Director, DR1 CNRS, PhD, PharmD
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A peptide mimetic of an anti-CD4 monoclonal antibody by rational design
F Casset, F Roux, P Mouchet, C Bes, T Chardes, C Granier, JC Mani, ...
Biochemical and biophysical research communications 307 (1), 198-205, 2003
6682003
Anti-HER2 vaccines: new prospects for breast cancer therapy
MZ Ladjemi, W Jacot, T Chardès, A Pèlegrin, I Navarro-Teulon
Cancer Immunology, Immunotherapy 59, 1295-1312, 2010
1722010
A neuronal isoform of nitric oxide synthase expressed in pancreatic β-cells controls insulin secretion
AD Lajoix, H Reggio, T Chardes, S Péraldi-Roux, F Tribillac, M Roye, ...
Diabetes 50 (6), 1311-1323, 2001
1602001
Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.
T Chardes, D Buzoni-Gatel, A Lepage, F Bernard, D Bout
Journal of immunology (Baltimore, Md.: 1950) 153 (10), 4596-4603, 1994
1561994
Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens
T Chardes, I Bourguin, MN Mevelec, JF Dubremetz, D Bout
Infection and Immunity 58 (5), 1240-1246, 1990
1471990
The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases
T Chardès, N Chapal, D Bresson, C Bès, V Giudicelli, MP Lefranc, ...
Immunogenetics 54, 141-157, 2002
1372002
Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding
D Laune, F Molina, G Ferrières, S Villard, C Bès, F Rieunier, T Chardès, ...
Journal of immunological methods 267 (1), 53-70, 2002
1112002
Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy
W Leconet, C Larbouret, T Chardès, G Thomas, M Neiveyans, M Busson, ...
Oncogene 33 (47), 5405-5414, 2014
1032014
Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies
MN Mevelec, T Chardès, O Mercereau-Puijalon, I Bourguin, A Achbarou, ...
Molecular and biochemical parasitology 56 (2), 227-238, 1992
1001992
In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of …
C Larbouret, N Gaborit, T Chardès, M Coelho, E Campigna, ...
Neoplasia 14 (2), 121-130, 2012
942012
Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice
I Bourguin, T Chardès, D Bout
Infection and immunity 61 (5), 2082-2088, 1993
931993
Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice.
T Chardes, F Velge-Roussel, P Mevelec, MN Mevelec, D Buzoni-Gatel, ...
Immunology 78 (3), 421, 1993
911993
Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using …
N Gaborit, C Larbouret, J Vallaghe, F Peyrusson, C Bascoul-Mollevi, ...
Journal of Biological Chemistry 286 (13), 11337-11345, 2011
852011
Localized irradiation of cell membrane by auger electrons is cytotoxic through oxidative stress-mediated nontargeted effects
S Paillas, R Ladjohounlou, C Lozza, A Pichard, V Boudousq, M Jarlier, ...
Antioxidants & redox signaling 25 (8), 467-484, 2016
832016
Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells
C Monnet, D Laune, J Laroche-Traineau, M Biard-Piechaczyk, L Briant, ...
Journal of Biological Chemistry 274 (6), 3789-3796, 1999
821999
Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies
Y Ashraf, H Mansouri, V Laurent-Matha, LB Alcaraz, P Roger, S Guiu, ...
Journal for Immunotherapy of Cancer 7, 1-17, 2019
732019
Protection against Chlamydia psittaci in mice conferred by Lyt-2+ T cells.
D Buzoni-Gatel, L Guilloteau, F Bernard, S Bernard, T Chardes, A Rocca
Immunology 77 (2), 284, 1992
711992
Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1
F Velge-Roussel, T Chardes, P Mévélec, M Brillard, J Hoebeke, D Bout
Molecular and biochemical parasitology 66 (1), 31-38, 1994
661994
Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases
D Bresson, M Cerutti, G Devauchelle, M Pugnière, F Roquet, C Bes, ...
Journal of Biological Chemistry 278 (11), 9560-9569, 2003
622003
Efficient amplification and direct sequencing of mouse variable regions from any immunoglobulin gene family
T Chardès, S Villard, G Ferrières, M Piechaczyk, M Cerutti, G Devauchelle, ...
FEBS letters 452 (3), 386-394, 1999
591999
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