Thomas Von Zglinicki
Thomas Von Zglinicki
Newcastle University and Near East University Nicosia, Northern Cyprus
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A DNA damage checkpoint response in telomere-initiated senescence
FA di Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, ...
Nature 426 (6963), 194-198, 2003
Oxidative stress shortens telomeres
T Von Zglinicki
Trends in biochemical sciences 27 (7), 339-344, 2002
Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?
T von Zglinicki, G Saretzki, W Döcke, C Lotze
Experimental cell research 220 (1), 186-193, 1995
Fat tissue, aging, and cellular senescence
T Tchkonia, DE Morbeck, T Von Zglinicki, J Van Deursen, J Lustgarten, ...
Aging cell 9 (5), 667-684, 2010
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
O Toussaint, EE Medrano, T von Zglinicki
Experimental gerontology 35 (8), 927-945, 2000
Feedback between p21 and reactive oxygen production is necessary for cell senescence
JF Passos, G Nelson, C Wang, T Richter, C Simillion, CJ Proctor, S Miwa, ...
Molecular systems biology 6 (1), 347, 2010
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
T von Zglinicki, R Pilger, N Sitte
Free Radical Biology and Medicine 28 (1), 64-74, 2000
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
JF Passos, G Saretzki, S Ahmed, G Nelson, T Richter, H Peters, I Wappler, ...
PLoS Biol 5 (5), e110, 2007
DNA damage response and cellular senescence in tissues of aging mice
C Wang, D Jurk, M Maddick, G Nelson, C Martin‐Ruiz, T Von Zglinicki
Aging cell 8 (3), 311-323, 2009
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ...
Nature communications 5 (1), 1-14, 2014
Role of oxidative stress in telomere length regulation and replicative senescence
T von Zglinicki
Annals of the New York Academy of Sciences 908 (1), 99-110, 2000
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts
S Petersen, G Saretzki, T von Zglinicki
Experimental cell research 239 (1), 152-160, 1998
Human cell senescence as a DNA damage response
T Von Zglinicki, G Saretzki, J Ladhoff, FA di Fagagna, SP Jackson
Mechanisms of ageing and development 126 (1), 111-117, 2005
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
AR Choudhury, Z Ju, MW Djojosubroto, A Schienke, A Lechel, ...
Nature genetics 39 (1), 99-105, 2007
A senescent cell bystander effect: Senescence‐induced senescence
G Nelson, J Wordsworth, C Wang, D Jurk, C Lawless, C Martin‐Ruiz, ...
Aging cell 11 (2), 345-349, 2012
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress
S Ahmed, JF Passos, MJ Birket, T Beckmann, S Brings, H Peters, ...
Journal of cell science 121 (7), 1046-1053, 2008
Health and disease in 85 year olds: baseline findings from the Newcastle 85+ cohort study
J Collerton, K Davies, C Jagger, A Kingston, J Bond, MP Eccles, ...
Bmj 339, 2009
Telomeres as biomarkers for ageing and age-related diseases
T Zglinicki, CM Martin-Ruiz
Current molecular medicine 5 (2), 197-203, 2005
Cellular senescence: defining a path forward
V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ...
Cell 179 (4), 813-827, 2019
Gender and telomere length: systematic review and meta-analysis
M Gardner, D Bann, L Wiley, R Cooper, R Hardy, D Nitsch, C Martin-Ruiz, ...
Experimental gerontology 51, 15-27, 2014
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