| Marine sponges as pharmacy D Sipkema, MCR Franssen, R Osinga, J Tramper, RH Wijffels Marine biotechnology 7 (3), 142, 2005 | 397 | 2005 |
| Large‐scale production of pharmaceuticals by marine sponges: Sea, cell, or synthesis? D Sipkema, R Osinga, W Schatton, D Mendola, J Tramper, RH Wijffels Biotechnology and bioengineering 90 (2), 201-222, 2005 | 192 | 2005 |
| NG-Tax, a highly accurate and validated pipeline for analysis of 16S rRNA amplicons from complex biomes J Ramiro-Garcia, GDA Hermes, C Giatsis, D Sipkema, EG Zoetendal, ... F1000Research 5, 2016 | 113 | 2016 |
| Multiple approaches to enhance the cultivability of bacteria associated with the marine sponge Haliclona (gellius) sp. D Sipkema, K Schippers, WJ Maalcke, Y Yang, S Salim, HW Blanch Applied and environmental microbiology 77 (6), 2130-2140, 2011 | 111 | 2011 |
| The impact of rearing environment on the development of gut microbiota in tilapia larvae C Giatsis, D Sipkema, H Smidt, H Heilig, G Benvenuti, J Verreth, ... Scientific reports 5 (1), 1-15, 2015 | 109 | 2015 |
| Bioprospecting sponge-associated microbes for antimicrobial compounds AAG Indraningrat, H Smidt, D Sipkema Marine drugs 14 (5), 87, 2016 | 105 | 2016 |
| The sponge microbiome project L Moitinho-Silva, S Nielsen, A Amir, A Gonzalez, GL Ackermann, ... Gigascience 6 (10), gix077, 2017 | 81 | 2017 |
| The multi-omics promise in context: from sequence to microbial isolate J Gutleben, M Chaib De Mares, JD van Elsas, H Smidt, J Overmann, ... Critical reviews in microbiology 44 (2), 212-229, 2018 | 74 | 2018 |
| Primmorphs from seven marine sponges: formation and structure D Sipkema, R Van Wielink, AAM Van Lammeren, J Tramper, R Osinga, ... Journal of biotechnology 100 (2), 127-139, 2003 | 73 | 2003 |
| Cultivation of sponges, sponge cells and symbionts: achievements and future prospects KJ Schippers, D Sipkema, R Osinga, H Smidt, SA Pomponi, DE Martens, ... Advances in marine biology 62, 273-337, 2012 | 72 | 2012 |
| Realizing the promises of marine biotechnology EEM Luiten, I Akkerman, A Koulman, P Kamermans, H Reith, MJ Barbosa, ... Biomolecular Engineering 20 (4-6), 429-439, 2003 | 62 | 2003 |
| Biological Characterisation of Haliclona (?gellius) sp.: Sponge and Associated Microorganisms D Sipkema, B Holmes, SA Nichols, HW Blanch Microbial Ecology 58 (4), 903, 2009 | 58 | 2009 |
| Effect of salinity on nitrification efficiency and structure of ammonia-oxidizing bacterial communities in a submerged fixed bed bioreactor C Cortés-Lorenzo, M Rodríguez-Díaz, D Sipkema, B Juárez-Jiménez, ... Chemical Engineering Journal 266, 233-240, 2015 | 56 | 2015 |
| Microbial community dynamics in a submerged fixed bed bioreactor during biological treatment of saline urban wastewater C Cortés-Lorenzo, D Sipkema, M Rodríguez-Díaz, S Fuentes, ... Ecological engineering 71, 126-132, 2014 | 52 | 2014 |
| Impact of a wastewater treatment plant on microbial community composition and function in a hyporheic zone of a eutrophic river S Atashgahi, R Aydin, MR Dimitrov, D Sipkema, K Hamonts, L Lahti, ... Scientific reports 5, 17284, 2015 | 51 | 2015 |
| Similar sponge‐associated bacteria can be acquired via both vertical and horizontal transmission D Sipkema, S de Caralt, JA Morillo, WA Al‐Soud, SJ Sørensen, H Smidt, ... Environmental microbiology 17 (10), 3807-3821, 2015 | 48 | 2015 |
| Mining microbial metatranscriptomes for expression of antibiotic resistance genes under natural conditions D Versluis, MM D’Andrea, JR Garcia, MM Leimena, F Hugenholtz, ... Scientific reports 5 (1), 1-10, 2015 | 47 | 2015 |
| The colonization dynamics of the gut microbiota in tilapia larvae C Giatsis, D Sipkema, H Smidt, J Verreth, M Verdegem PLoS One 9 (7), e103641, 2014 | 46 | 2014 |
| Marine rare actinomycetes: a promising source of structurally diverse and unique novel natural products R Subramani, D Sipkema Marine drugs 17 (5), 249, 2019 | 44 | 2019 |
| The effect of the algal microbiome on industrial production of microalgae J Lian, RH Wijffels, H Smidt, D Sipkema Microbial biotechnology 11 (5), 806-818, 2018 | 39 | 2018 |
