Elongator controls the migration and differentiation of cortical neurons through acetylation of α-tubulin C Creppe, L Malinouskaya, ML Volvert, M Gillard, P Close, O Malaise, ... Cell 136 (3), 551-564, 2009 | 564 | 2009 |
Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia P Close, N Hawkes, I Cornez, C Creppe, CA Lambert, B Rogister, ... Molecular cell 22 (4), 521-531, 2006 | 234 | 2006 |
Codon-specific translation reprogramming promotes resistance to targeted therapy F Rapino, S Delaunay, F Rambow, Z Zhou, L Tharun, P De Tullio, O Sin, ... Nature 558 (7711), 605-609, 2018 | 211 | 2018 |
A dynamic unfolded protein response contributes to the control of cortical neurogenesis S Laguesse, C Creppe, DD Nedialkova, PP Prevot, L Borgs, S Huysseune, ... Developmental cell 35 (5), 553-567, 2015 | 194 | 2015 |
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer S Delaunay, F Rapino, L Tharun, Z Zhou, L Heukamp, M Termathe, ... Journal of Experimental Medicine 213 (11), 2503-2523, 2016 | 157 | 2016 |
DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation P Close, P East, AB Dirac-Svejstrup, H Hartmann, M Heron, S Maslen, ... Nature 484 (7394), 386-389, 2012 | 147 | 2012 |
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells E Buytaert, JY Matroule, S Durinck, P Close, S Kocanova, ... Oncogene 27 (13), 1916-1929, 2008 | 119 | 2008 |
NF-κB-induced KIAA1199 promotes survival through EGFR signalling K Shostak, X Zhang, P Hubert, SI Göktuna, Z Jiang, I Klevernic, ... Nature communications 5 (1), 5232, 2014 | 116 | 2014 |
p27Kip1 is a microtubule-associated protein that promotes microtubule polymerization during neuron migration JD Godin, N Thomas, S Laguesse, L Malinouskaya, P Close, O Malaise, ... Developmental cell 23 (4), 729-744, 2012 | 113 | 2012 |
Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKϵ-dependent Lys63-linked polyubiquitination and phosphorylation of TANK/I-TRAF JS Gatot, R Gioia, TL Chau, F Patrascu, M Warnier, P Close, JP Chapelle, ... Journal of biological chemistry 282 (43), 31131-31146, 2007 | 108 | 2007 |
The emerging role of lysine acetylation of non-nuclear proteins P Close, C Creppe, M Gillard, A Ladang, JP Chapelle, L Nguyen, ... Cellular and Molecular Life Sciences 67, 1255-1264, 2010 | 92 | 2010 |
MicroRNA targeting of CoREST controls polarization of migrating cortical neurons ML Volvert, PP Prevot, P Close, S Laguesse, S Pirotte, J Hemphill, ... Cell reports 7 (4), 1168-1183, 2014 | 83 | 2014 |
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine A Ladang, F Rapino, LC Heukamp, L Tharun, K Shostak, D Hermand, ... Journal of Experimental Medicine 212 (12), 2057-2075, 2015 | 75 | 2015 |
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine A Ladang, F Rapino, LC Heukamp, L Tharun, K Shostak, D Hermand, ... Journal of Experimental Medicine 212 (12), 2057-2075, 2015 | 75 | 2015 |
Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-κB inhibition and gene expression signature S Olivier, P Close, E Castermans, L De Leval, S Tabruyn, A Chariot, ... Molecular Pharmacology 69 (5), 1615-1623, 2006 | 67 | 2006 |
DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator P Close, M Gillard, A Ladang, Z Jiang, J Papuga, N Hawkes, L Nguyen, ... Journal of Biological Chemistry 287 (39), 32535-32545, 2012 | 56 | 2012 |
Developments in the pharmacotherapeutic management of osteoporosis P Close, A Neuprez, JY Reginster Expert Opinion on Pharmacotherapy 7 (12), 1603-1615, 2006 | 54 | 2006 |
tRNA modification: is cancer having a wobble? F Rapino, S Delaunay, Z Zhou, A Chariot, P Close Trends in cancer 3 (4), 249-252, 2017 | 51 | 2017 |
Involvement of placental growth factor in Wallerian degeneration L Chaballe, P Close, M Sempels, S Delstanche, J Fanielle, L Moons, ... Glia 59 (3), 379-396, 2011 | 49 | 2011 |
TNFα-and IKKβ-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKγ and NF-κB activation M Bonif, MA Meuwis, P Close, V Benoit, K Heyninck, JP Chapelle, ... Biochemical Journal 394 (3), 593-603, 2006 | 45 | 2006 |