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Alexander L. Tobias
Alexander L. Tobias
Resident Physician, Vanderbilt University Medical Center
Dirección de correo verificada de vumc.org
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Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
DA Wainwright, AL Chang, M Dey, IV Balyasnikova, CK Kim, A Tobias, ...
Clinical cancer research 20 (20), 5290-5301, 2014
6002014
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival
DA Wainwright, IV Balyasnikova, AL Chang, AU Ahmed, KS Moon, ...
Clinical cancer research 18 (22), 6110-6121, 2012
4412012
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
B Auffinger, AL Tobias, Y Han, G Lee, D Guo, M Dey, MS Lesniak, ...
Cell Death & Differentiation 21 (7), 1119-1131, 2014
3682014
Multifunctional nanoparticles for brain tumor imaging and therapy
Y Cheng, RA Morshed, B Auffinger, AL Tobias, MS Lesniak
Advanced drug delivery reviews 66, 42-57, 2014
3442014
Blood‐brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging
Y Cheng, Q Dai, RA Morshed, X Fan, ML Wegscheid, DA Wainwright, ...
Small 10 (24), 5137-5150, 2014
2712014
Intranasal delivery of mesenchymal stem cells significantly extends survival of irradiated mice with experimental brain tumors
IV Balyasnikova, MS Prasol, SD Ferguson, Y Han, AU Ahmed, M Gutova, ...
Molecular Therapy 22 (1), 140-148, 2014
1272014
The art of gene therapy for glioma: a review of the challenging road to the bedside
A Tobias, A Ahmed, KS Moon, MS Lesniak
Journal of Neurology, Neurosurgery & Psychiatry 84 (2), 213-222, 2013
1202013
A preclinical evaluation of neural stem cell–based cell carrier for targeted antiglioma oncolytic virotherapy
AU Ahmed, B Thaci, AL Tobias, B Auffinger, L Zhang, Y Cheng, CK Kim, ...
Journal of the National Cancer Institute 105 (13), 968-977, 2013
1082013
Dedifferentiation of glioma cells to glioma stem-like cells by therapeutic stress-induced HIF signaling in the recurrent GBM model
G Lee, B Auffinger, D Guo, T Hasan, M Deheeger, AL Tobias, JY Kim, ...
Molecular cancer therapeutics 15 (12), 3064-3076, 2016
1042016
Nanoparticle‐programmed self‐destructive neural stem cells for glioblastoma targeting and therapy
Y Cheng, R Morshed, SH Cheng, A Tobias, B Auffinger, DA Wainwright, ...
Small 9 (24), 4123-4129, 2013
972013
Drug-loaded nanoparticle systems and adult stem cells: a potential marriage for the treatment of malignant glioma?
B Auffinger, R Morshed, A Tobias, Y Cheng, AU Ahmed, MS Lesniak
Oncotarget 4 (3), 378, 2013
922013
Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: targeted delivery of the therapeutic payload in an orthotopic brain tumor model
B Thaci, AU Ahmed, IV Ulasov, AL Tobias, Y Han, KS Aboody, ...
Cancer gene therapy 19 (6), 431-442, 2012
922012
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma
AL Tobias, B Thaci, B Auffinger, E Rincón, IV Balyasnikova, CK Kim, ...
Stem cells translational medicine 2 (9), 655-666, 2013
892013
Dendritic cell–based vaccines that utilize myeloid rather than plasmacytoid cells offer a superior survival advantage in malignant glioma
M Dey, AL Chang, J Miska, DA Wainwright, AU Ahmed, IV Balyasnikova, ...
The Journal of Immunology 195 (1), 367-376, 2015
602015
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma
B Thaci, AU Ahmed, IV Ulasov, DA Wainwright, P Nigam, B Auffinger, ...
Cancer gene therapy 21 (1), 38-44, 2014
382014
N-acetylcysteine amide augments the therapeutic effect of neural stem cell-based antiglioma oncolytic virotherapy
CK Kim, AU Ahmed, B Auffinger, IV Ulasov, AL Tobias, KS Moon, ...
Molecular Therapy 21 (11), 2063-2073, 2013
282013
MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells
NG Alexiades, B Auffinger, CK Kim, T Hasan, G Lee, M Deheeger, ...
Stem cell research 15 (3), 598-607, 2015
192015
Correction: Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
DA Wainwright, AL Chang, M Dey, IV Balyasnikova, CK Kim, A Tobias
Clinical Cancer Research 21 (3), 662, 2015
12015
Sc-02conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
B Auffinger, A Tobias, Y Han, G Lee, D Guo, M Dey, M Lesniak, A Ahmed
Neuro-Oncology 16 (Suppl 5), v197, 2014
12014
Gold nanoparticles as a drug delivery system for malignant brain tumors
Y Cheng, Q Dai, R Morshed, Y Han, B Auffinger, D Wainwright, L Zhang, ...
NEURO-ONCOLOGY 15, 39-40, 2013
12013
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