Chris Bakal
Chris Bakal
Team Leader, Chester Beatty Laboratories, Institute of Cancer Research
Dirección de correo verificada de icr.ac.uk
TítuloCitado porAño
The MAGUK family protein CARD11 is essential for lymphocyte activation
H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ...
Immunity 18 (6), 763-775, 2003
3362003
Quantitative morphological signatures define local signaling networks regulating cell morphology
C Bakal, J Aach, G Church, N Perrimon
science 316 (5832), 1753-1756, 2007
2802007
Genomic screening with RNAi: results and challenges
S Mohr, C Bakal, N Perrimon
Annual review of biochemistry 79, 37-64, 2010
2672010
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ...
The Journal of experimental medicine 199 (3), 399-410, 2004
1452004
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds
C Bakal, R Linding, F Llense, E Heffern, E Martin-Blanco, T Pawson, ...
science 322 (5900), 453-456, 2008
1352008
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ...
Nature cell biology 15 (7), 860-871, 2013
1222013
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ...
Nature communications 8 (1), 1-17, 2017
922017
Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells
JE Sero, HZ Sailem, RC Ardy, H Almuttaqi, T Zhang, C Bakal
Molecular systems biology 11 (3), 2015
892015
Enhancing light absorption and charge transfer efficiency in carbon dots through graphitization and core nitrogen doping
BCM Martindale, GAM Hutton, CA Caputo, S Prantl, R Godin, JR Durrant, ...
Angewandte Chemie International Edition 56 (23), 6459-6463, 2017
792017
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis
R Natrajan, H Sailem, FK Mardakheh, MA Garcia, CJ Tape, M Dowsett, ...
PLoS medicine 13 (2), 2016
672016
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ...
Clinical cancer research 23 (18), 5561-5572, 2017
642017
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition
D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ...
Molecular cell 45 (5), 642-655, 2012
602012
The twin spot generator for differential Drosophila lineage analysis
R Griffin, A Sustar, M Bonvin, R Binari, A del Valle Rodriguez, AM Hohl, ...
Nature methods 6 (8), 600, 2009
572009
A dynamical framework for the all-or-none G1/S transition
AR Barr, FS Heldt, T Zhang, C Bakal, B Novák
Cell systems 2 (1), 27-37, 2016
552016
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens
Z Yin, X Zhou, C Bakal, F Li, Y Sun, N Perrimon, STC Wong
BMC bioinformatics 9 (1), 264, 2008
502008
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
H Sailem, V Bousgouni, S Cooper, C Bakal
Open biology 4 (1), 130132, 2014
482014
Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning
JE Sero, CK Thodeti, A Mammoto, C Bakal, S Thomas, DE Ingber
PloS one 6 (12), 2011
382011
RNAiCut: automated detection of significant genes from functional genomic screens
IM Kaplow, R Singh, A Friedman, C Bakal, N Perrimon, B Berger
Nature methods 6 (7), 476-477, 2009
292009
Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen
O Nir, C Bakal, N Perrimon, B Berger
Genome research 20 (3), 372-380, 2010
282010
Visualizing cellular imaging data using PhenoPlot
HZ Sailem, JE Sero, C Bakal
Nature communications 6, 5825, 2015
272015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20