FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis T Matsuzaki, O Alvarez-Garcia, S Mokuda, K Nagira, M Olmer, R Gamini, ... Science translational medicine 10 (428), eaan0746, 2018 | 241 | 2018 |
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice T Matsuzaki, T Matsushita, K Takayama, T Matsumoto, K Nishida, ... Annals of the rheumatic diseases 73 (7), 1397-1404, 2014 | 179 | 2014 |
The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin‐1β in human chondrocytes T Matsushita, H Sasaki, K Takayama, K Ishida, T Matsumoto, S Kubo, ... Journal of Orthopaedic Research 31 (4), 531-537, 2013 | 132 | 2013 |
A radiographic analysis of alignment of the lower extremities–initiation and progression of varus-type knee osteoarthritis T Matsumoto, M Hashimura, K Takayama, K Ishida, Y Kawakami, ... Osteoarthritis and cartilage 23 (2), 217-223, 2015 | 126 | 2015 |
Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes K Nagai, T Matsushita, T Matsuzaki, K Takayama, T Matsumoto, R Kuroda, ... Osteoarthritis and cartilage 23 (8), 1412-1420, 2015 | 95 | 2015 |
Intra-articular administration of gelatin hydrogels incorporating rapamycin–micelles reduces the development of experimental osteoarthritis in a murine model T Matsuzaki, T Matsushita, Y Tabata, T Saito, T Matsumoto, K Nagai, ... Biomaterials 35 (37), 9904-9911, 2014 | 95 | 2014 |
Wwp2 maintains cartilage homeostasis through regulation of Adamts5 S Mokuda, R Nakamichi, T Matsuzaki, Y Ito, T Sato, K Miyata, M Inui, ... Nature communications 10 (1), 2429, 2019 | 82 | 2019 |
Regulated in development and DNA damage response 1 deficiency impairs autophagy and mitochondrial biogenesis in articular cartilage and increases the severity of experimental … O Alvarez‐Garcia, T Matsuzaki, M Olmer, L Plate, JW Kelly, MK Lotz Arthritis & rheumatology 69 (7), 1418-1428, 2017 | 76 | 2017 |
Age‐related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration O Alvarez‐Garcia, T Matsuzaki, M Olmer, K Masuda, MK Lotz Journal of Orthopaedic Research 35 (12), 2682-2691, 2017 | 66 | 2017 |
Local administration of low-dose simvastatin-conjugated gelatin hydrogel for tendon–bone healing in anterior cruciate ligament reconstruction S Oka, T Matsumoto, S Kubo, T Matsushita, H Sasaki, Y Nishizawa, ... Tissue Engineering Part A 19 (9-10), 1233-1243, 2013 | 66 | 2013 |
FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis KI Lee, S Choi, T Matsuzaki, O Alvarez-Garcia, M Olmer, SP Grogan, ... Proceedings of the National Academy of Sciences 117 (6), 3135-3143, 2020 | 63 | 2020 |
FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration O Alvarez‐Garcia, T Matsuzaki, M Olmer, K Miyata, S Mokuda, D Sakai, ... Aging cell 17 (5), e12800, 2018 | 62 | 2018 |
Tibial internal rotation is affected by lateral laxity in cruciate-retaining total knee arthroplasty: an intraoperative kinematic study using a navigation system and offset … T Matsuzaki, T Matsumoto, S Kubo, H Muratsu, T Matsushita, Y Kawakami, ... Knee Surgery, Sports Traumatology, Arthroscopy 22, 615-620, 2014 | 53 | 2014 |
Kinematic factors affecting postoperative knee flexion after cruciate-retaining total knee arthroplasty T Matsuzaki, T Matsumoto, H Muratsu, S Kubo, T Matsushita, Y Kawakami, ... International orthopaedics 37, 803-808, 2013 | 53 | 2013 |
Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis Y Akasaki, N Reixach, T Matsuzaki, O Alvarez‐Garcia, M Olmer, ... Arthritis & Rheumatology 67 (8), 2097-2107, 2015 | 50 | 2015 |
Both microRNA-455-5p and-3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis Y Ito, T Matsuzaki, F Ayabe, S Mokuda, R Kurimoto, T Matsushima, ... Nature communications 12 (1), 4148, 2021 | 49 | 2021 |
Different pattern in gap balancing between the cruciate-retaining and posterior-stabilized total knee arthroplasty T Matsumoto, S Kubo, H Muratsu, T Matsushita, K Ishida, Y Kawakami, ... Knee Surgery, Sports Traumatology, Arthroscopy 21, 2338-2345, 2013 | 41 | 2013 |
Anterior cruciate ligament remnant tissue harvested within 3-months after injury predicts higher healing potential S Zhang, T Matsumoto, A Uefuji, T Matsushita, K Takayama, D Araki, ... BMC Musculoskeletal Disorders 16, 1-9, 2015 | 36 | 2015 |
Local administration of simvastatin stimulates healing of an avascular meniscus in a rabbit model of a meniscal defect S Zhang, T Matsushita, R Kuroda, K Nishida, T Matsuzaki, T Matsumoto, ... The American Journal of Sports Medicine 44 (7), 1735-1743, 2016 | 31 | 2016 |
Intraoperative soft tissue balance/kinematics and clinical evaluation of modified kinematically versus mechanically aligned total knee arthroplasty T Matsumoto, K Takayama, K Ishida, Y Kuroda, M Tsubosaka, H Muratsu, ... The journal of knee surgery 33 (08), 777-784, 2020 | 29 | 2020 |