CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome F Taube, JA Georgi, M Kramer, S Stasik, JM Middeke, C Röllig, U Krug, ... Blood, The Journal of the American Society of Hematology 139 (1), 87-103, 2022 | 95 | 2022 |
Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia S Ottema, R Mulet-Lazaro, HB Beverloo, C Erpelinck, S van Herk, ... Blood, The Journal of the American Society of Hematology 136 (2), 224-234, 2020 | 46 | 2020 |
PopHuman: the human population genomics browser S Casillas, R Mulet, P Villegas-Miron, S Hervas, E Sanz, D Velasco, ... Nucleic acids research 46 (D1), D1003-D1010, 2018 | 40 | 2018 |
Novel neuroprotective multicomponent therapy for amyotrophic lateral sclerosis designed by networked systems M Herrando-Grabulosa, R Mulet, A Pujol, JM Mas, X Navarro, P Aloy, ... PLoS One 11 (1), e0147626, 2016 | 36 | 2016 |
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops S Ottema, R Mulet-Lazaro, C Erpelinck-Verschueren, S van Herk, ... Nature Communications 12 (1), 5679, 2021 | 34 | 2021 |
Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia L Smeenk, S Ottema, R Mulet-Lazaro, A Ebert, M Havermans, AA Varea, ... Cancer discovery 11 (11), 2868-2883, 2021 | 28 | 2021 |
Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia A Tanaka, TA Nakano, M Nomura, H Yamazaki, JP Bewersdorf, ... Blood, The Journal of the American Society of Hematology 140 (8), 875-888, 2022 | 15 | 2022 |
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML R Mulet-Lazaro, S van Herk, C Erpelinck, E Bindels, MA Sanders, ... Blood, The Journal of the American Society of Hematology 138 (2), 160-177, 2021 | 14 | 2021 |
Systems biology applied to non-alcoholic fatty liver disease (NAFLD): treatment selection based on the mechanism of action of nutraceuticals S Perera, L Artigas, R Mulet, JM Mas, T Sardón Nutrafoods 13, 61-68, 2014 | 13 | 2014 |
Aberrant DNA methylation patterns in microsatellite stable human colorectal cancers define a new marker panel for the CpG island methylator phenotype C Gebhard, R Mulet-Lazaro, D Glatz, L Schwarzfischer-Pfeilschifter, ... International journal of cancer, 2021 | 3 | 2021 |
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency A Rein, I Geron, E Kugler, H Fishman, E Gottlieb, I Abramovich, A Giladi, ... Haematologica 108 (9), 2316, 2023 | 2 | 2023 |
Induced cell-autonomous neutropenia systemically perturbs hematopoiesis in Cebpa enhancer-null mice R Avellino, R Mulet-Lazaro, M Havermans, R Hoogenboezem, L Smeenk, ... Blood advances 6 (5), 1406-1419, 2022 | 2 | 2022 |
Tumor-specific super-enhancer drives overexpression of EVI1 in ovarian cancer L Smeenk, S Kruse, R Mulet-Lazaro, I Boere, J Martens, S Gröschel, ... Cancer Research 84 (6_Supplement), 3040-3040, 2024 | | 2024 |
Targeting Super-Enhancers Driving EVI1 Expression in Leukemia By Inhibition of p300/CBP D Pastoors, C Erpelinck, S Van Herk, R Mulet-Lazaro, M Havermans, ... Blood 142, 710, 2023 | | 2023 |
From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis R Mulet-Lazaro, R Delwel HemaSphere 7 (11), e969, 2023 | | 2023 |
Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2 D Pastoors, M Havermans, R Mulet-Lazaro, D Brian, W Noort, J Grasel, ... bioRxiv, 2023.07. 11.548358, 2023 | | 2023 |
Cohesin-STAG2 Mutations Alter Chromatin Structure and Gene Regulation in Human Acute Myeloid Leukemia A Fischer, R Mulet-Lazaro, M Nützel, S van Herk, H Stanewsky, ... Blood 140 (Supplement 1), 3379-3380, 2022 | | 2022 |
Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA D Pastoors, M Havermans, R Hoogenboezem, R Mulet-Lazaro, D Brian, ... Blood 140 (Supplement 1), 83-84, 2022 | | 2022 |
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML (vol 138, pg 160, 2021) R Mulet-Lazaro, S van Herk, C Erpelinck BLOOD 139 (11), 1772-1772, 2022 | | 2022 |
The CBFβ-SMMHC/NRP1 Axis Regulates FLT3 and TGF-Beta Pathways in Inv (16) Acute Myeloid Leukemia M Hegde, MH Ahmad, R Li, A Carrascoso, R Mulet-Lazaro, R Delwel, ... Blood 138, 3314, 2021 | | 2021 |