Nahum Sonenberg

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anne-claude gingrasLunenfeld-Tanenbaum Research Institute; University of TorontoVerified email at lunenfeld.ca
Brian RaughtSenior Scientist, Princess Margaret Cancer CentreVerified email at uhnres.utoronto.ca
ivan topisirovicProfessor, McGill, Lady Davis InstituteVerified email at mcgill.ca
Arnim Pause, M.Sc., Ph.D.Professor, Department of Biochemistry, Goodman Cencer Research Centre, McGill UniversityVerified email at mcgill.ca
Tommy AlainChildren's Hospital of Eastern Ontario Research Institute and University of OttawaVerified email at arc.cheo.ca
Arkady KhoutorskyMcGill UniversityVerified email at mcgill.ca
Christos G. GkogkasPrincipal Investigator: FORTH-BRI, GreeceVerified email at bri.forth.gr
Ola LarssonAssociate professor, Karolinska InstitutetVerified email at ki.se
William MerrickCase Western Reserve UniversityVerified email at case.edu
Akiko YanagiyaVerified email at oist.jp
Stephen K. Burley, M.D., D.Phil.Institute for Quantitative Biomedicine, Rutgers UniversityVerified email at proteomics.rutgers.edu
John BellProfessor of Medicine, University of OttawaVerified email at ohri.ca
Jean-Claude LacailleDept Neurosciences, Université de MontréalVerified email at umontreal.ca
Paul LaskoDepartment of Biology, McGill UniversityVerified email at mcgill.ca
Masahiro MoritaTenure-Track Assistant Professor (principal investigator), Department of Molecular Medicine andVerified email at uthscsa.edu
Graham J. BelshamProf. of Veterinary Virology, University of CopenhagenVerified email at sund.ku.dk
David ShahbazianTrans-Hit BioVerified email at trans-hit.com
Nathaniel RobichaudNomic BioVerified email at nomic.bio
Michael PollakMcGill UniversityVerified email at mcgill.ca
Nissim HayVerified email at uic.edu

Nahum Sonenberg

Gilman Cheney Professor in Biochemistry

Verified email at mcgill.ca - Homepage

mRNA Translation in cancer and mental diseases


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? W Filipowicz, SN Bhattacharyya, N Sonenberg Nature reviews genetics 9 (2), 102-114, 2008	6407	2008
Upstream and downstream of mTOR N Hay, N Sonenberg Genes & development 18 (16), 1926-1945, 2004	5412	2004
Regulation of translation initiation in eukaryotes: mechanisms and biological targets N Sonenberg, AG Hinnebusch Cell 136 (4), 731-745, 2009	3696	2009
Regulation of mRNA translation and stability by microRNAs MR Fabian, N Sonenberg, W Filipowicz Annual review of biochemistry 79, 351-379, 2010	3567	2010
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation AC Gingras, B Raught, N Sonenberg Annual review of biochemistry 68 (1), 913-963, 1999	2740	1999
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA J Pelletier, N Sonenberg Nature 334 (6180), 320-325, 1988	2599	1988
Regulation of translation initiation by FRAP/mTOR AC Gingras, B Raught, N Sonenberg Genes & development 15 (7), 807-826, 2001	1764	2001
Translational control in stress and apoptosis M Holcik, N Sonenberg Nature reviews Molecular cell biology 6 (4), 318-327, 2005	1682	2005
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ... Genes & development 13 (11), 1422-1437, 1999	1628	1999
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function A Pause, GJ Belsham, AC Gingras, O Donzé, TA Lin, JC Lawrence Jr, ... Nature 371 (6500), 762-767, 1994	1612	1994
Metformin is an AMP kinase–dependent growth inhibitor for breast cancer cells M Zakikhani, R Dowling, IG Fantus, N Sonenberg, M Pollak Cancer research 66 (21), 10269-10273, 2006	1320	2006
Regulation of cap-dependent translation by eIF4E inhibitory proteins JD Richter, N Sonenberg Nature 433 (7025), 477-480, 2005	1242	2005
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5'cap A Lazaris-Karatzas, KS Montine, N Sonenberg Nature 345 (6275), 544-547, 1990	1235	1990
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ... Immunity 21 (1), 81-93, 2004	1195	2004
Hierarchical phosphorylation of the translation inhibitor 4E-BP1 AC Gingras, B Raught, SP Gygi, A Niedzwiecka, M Miron, SK Burley, ... Genes & development 15 (21), 2852-2864, 2001	1139	2001
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway AC Gingras, SG Kennedy, MA O’Leary, N Sonenberg, N Hay Genes & development 12 (4), 502-513, 1998	1138	1998
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC MR Fabian, N Sonenberg Nature structural & molecular biology 19 (6), 586-593, 2012	1136	2012
Metformin inhibits mammalian target of rapamycin–dependent translation initiation in breast cancer cells RJO Dowling, M Zakikhani, IG Fantus, M Pollak, N Sonenberg Cancer research 67 (22), 10804-10812, 2007	1118	2007
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus DF Stojdl, B Lichty, S Knowles, R Marius, H Atkins, N Sonenberg, JC Bell Nature medicine 6 (7), 821-825, 2000	1066	2000
The mRNA 5′ cap-binding protein eIF4E and control of cell growth N Sonenberg, AC Gingras Current opinion in cell biology 10 (2), 268-275, 1998	1061	1998

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