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Fraser Fleming
Fraser Fleming
Professor of Chemistry, Drexel University
Dirección de correo verificada de drexel.edu - Página principal
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Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore
FF Fleming, L Yao, PC Ravikumar, L Funk, BC Shook
Journal of medicinal chemistry 53 (22), 7902-7917, 2010
15362010
Nitrile-containing natural products
FF Fleming
Natural Product Reports 16 (5), 597-606, 1999
6071999
Unsaturated nitriles: conjugate additions of carbon nucleophiles to a recalcitrant class of acceptors
FF Fleming, Q Wang
Chemical reviews 103 (5), 2035-2078, 2003
3822003
Nitrile anion cyclizations
FF Fleming, BC Shook
Tetrahedron 58 (1), 1-23, 2002
1772002
Catalytic isonitrile insertions and condensations initiated by RNC–X complexation
S Chakrabarty, S Choudhary, A Doshi, FQ Liu, R Mohan, MP Ravindra, ...
Advanced synthesis & catalysis 356 (10), 2135-2196, 2014
1392014
Cyclic nitriles: tactical advantages in synthesis
FF Fleming, Z Zhang
Tetrahedron 61 (4), 747-789, 2005
1292005
Pd-Catalyzed α-Arylation of nitriles and esters and γ-Arylation of unsaturated nitriles with TMPZnCl· LiCl
S Duez, S Bernhardt, J Heppekausen, FF Fleming, P Knochel
Organic Letters 13 (7), 1690-1693, 2011
922011
Metalated Nitriles: Organolithium,-magnesium, and-copper Exchange of α-Halonitriles
FF Fleming, Z Zhang, W Liu, P Knochel
The Journal of Organic Chemistry 70 (6), 2200-2205, 2005
792005
Fatty acid amide biosynthesis: a possible new role for peptidylglycine a-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase
DJ Merkler, KA Merkler, W Stern, FF Fleming
Archives of biochemistry and biophysics 330 (2), 430, 1996
791996
Iminyl-radical-triggered C–C bond cleavage of cycloketone oxime derivatives: generation of distal cyano-substituted alkyl radicals and their functionalization
T Xiao, H Huang, D Anand, L Zhou
Synthesis 52 (11), 1585-1601, 2020
702020
C-and N-metalated nitriles: the relationship between structure and selectivity
X Yang, FF Fleming
Accounts of Chemical Research 50 (10), 2556-2568, 2017
562017
Deprotecting dithiane-containing alkaloids
FF Fleming, L Funk, R Altundas, Y Tu
The Journal of Organic Chemistry 66 (19), 6502-6504, 2001
552001
Alkynenitriles: Chelation-controlled conjugate additions
FF Fleming, V Gudipati, OW Steward
Organic Letters 4 (4), 659-661, 2002
532002
Metalated nitriles: N-and C-coordination preferences of Li, Mg, and Cu cations
M Purzycki, W Liu, G Hilmersson, FF Fleming
Chemical communications 49 (41), 4700-4702, 2013
462013
Alkyl sulfinates: Formal nucleophiles for synthesizing TosMIC analogs
JA Lujan‐Montelongo, AO Estevez, FF Fleming
European journal of organic chemistry 2015 (7), 1602-1605, 2015
442015
α, β-unsaturated nitriles: Stereoselective conjugate addition reactions
FF Fleming, Z Hussain, D Weaver, RE Norman
The Journal of Organic Chemistry 62 (5), 1305-1309, 1997
441997
Metalated nitriles: Internal 1, 2-asymmetric induction
FF Fleming, W Liu, S Ghosh, OW Steward
The Journal of Organic Chemistry 73 (7), 2803-2810, 2008
432008
Grignard Reagents:  Alkoxide-Directed Iodine−Magnesium Exchange at sp3 Centers
FF Fleming, S Gudipati, VA Vu, RJ Mycka, P Knochel
Organic Letters 9 (22), 4507-4509, 2007
372007
C-Metalated Nitriles:  Electrophile-Dependent Alkylations and Acylations
FF Fleming, Z Zhang, G Wei, OW Steward
The Journal of organic chemistry 71 (4), 1430-1435, 2006
372006
Cyclic nitriles: Diastereoselective alkylations
FF Fleming, S Gudipati, Z Zhang, W Liu, OW Steward
The Journal of Organic Chemistry 70 (10), 3845-3849, 2005
372005
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