Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore FF Fleming, L Yao, PC Ravikumar, L Funk, BC Shook Journal of medicinal chemistry 53 (22), 7902-7917, 2010 | 1536 | 2010 |
Nitrile-containing natural products FF Fleming Natural Product Reports 16 (5), 597-606, 1999 | 607 | 1999 |
Unsaturated nitriles: conjugate additions of carbon nucleophiles to a recalcitrant class of acceptors FF Fleming, Q Wang Chemical reviews 103 (5), 2035-2078, 2003 | 382 | 2003 |
Nitrile anion cyclizations FF Fleming, BC Shook Tetrahedron 58 (1), 1-23, 2002 | 177 | 2002 |
Catalytic isonitrile insertions and condensations initiated by RNC–X complexation S Chakrabarty, S Choudhary, A Doshi, FQ Liu, R Mohan, MP Ravindra, ... Advanced synthesis & catalysis 356 (10), 2135-2196, 2014 | 139 | 2014 |
Cyclic nitriles: tactical advantages in synthesis FF Fleming, Z Zhang Tetrahedron 61 (4), 747-789, 2005 | 129 | 2005 |
Pd-Catalyzed α-Arylation of nitriles and esters and γ-Arylation of unsaturated nitriles with TMPZnCl· LiCl S Duez, S Bernhardt, J Heppekausen, FF Fleming, P Knochel Organic Letters 13 (7), 1690-1693, 2011 | 92 | 2011 |
Metalated Nitriles: Organolithium,-magnesium, and-copper Exchange of α-Halonitriles FF Fleming, Z Zhang, W Liu, P Knochel The Journal of Organic Chemistry 70 (6), 2200-2205, 2005 | 79 | 2005 |
Fatty acid amide biosynthesis: a possible new role for peptidylglycine a-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase DJ Merkler, KA Merkler, W Stern, FF Fleming Archives of biochemistry and biophysics 330 (2), 430, 1996 | 79 | 1996 |
Iminyl-radical-triggered C–C bond cleavage of cycloketone oxime derivatives: generation of distal cyano-substituted alkyl radicals and their functionalization T Xiao, H Huang, D Anand, L Zhou Synthesis 52 (11), 1585-1601, 2020 | 70 | 2020 |
C-and N-metalated nitriles: the relationship between structure and selectivity X Yang, FF Fleming Accounts of Chemical Research 50 (10), 2556-2568, 2017 | 56 | 2017 |
Deprotecting dithiane-containing alkaloids FF Fleming, L Funk, R Altundas, Y Tu The Journal of Organic Chemistry 66 (19), 6502-6504, 2001 | 55 | 2001 |
Alkynenitriles: Chelation-controlled conjugate additions FF Fleming, V Gudipati, OW Steward Organic Letters 4 (4), 659-661, 2002 | 53 | 2002 |
Metalated nitriles: N-and C-coordination preferences of Li, Mg, and Cu cations M Purzycki, W Liu, G Hilmersson, FF Fleming Chemical communications 49 (41), 4700-4702, 2013 | 46 | 2013 |
Alkyl sulfinates: Formal nucleophiles for synthesizing TosMIC analogs JA Lujan‐Montelongo, AO Estevez, FF Fleming European journal of organic chemistry 2015 (7), 1602-1605, 2015 | 44 | 2015 |
α, β-unsaturated nitriles: Stereoselective conjugate addition reactions FF Fleming, Z Hussain, D Weaver, RE Norman The Journal of Organic Chemistry 62 (5), 1305-1309, 1997 | 44 | 1997 |
Metalated nitriles: Internal 1, 2-asymmetric induction FF Fleming, W Liu, S Ghosh, OW Steward The Journal of Organic Chemistry 73 (7), 2803-2810, 2008 | 43 | 2008 |
Grignard Reagents: Alkoxide-Directed Iodine−Magnesium Exchange at sp3 Centers FF Fleming, S Gudipati, VA Vu, RJ Mycka, P Knochel Organic Letters 9 (22), 4507-4509, 2007 | 37 | 2007 |
C-Metalated Nitriles: Electrophile-Dependent Alkylations and Acylations FF Fleming, Z Zhang, G Wei, OW Steward The Journal of organic chemistry 71 (4), 1430-1435, 2006 | 37 | 2006 |
Cyclic nitriles: Diastereoselective alkylations FF Fleming, S Gudipati, Z Zhang, W Liu, OW Steward The Journal of Organic Chemistry 70 (10), 3845-3849, 2005 | 37 | 2005 |