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Benjamin Fabre
Benjamin Fabre
Institute of Organic Chemistry and Biochemistry, Prague
Dirección de correo verificada de uochb.cas.cz
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Targeting matrix metalloproteinases: exploring the dynamics of the S1′ pocket in the design of selective, small molecule inhibitors: miniperspective
B Fabre, A Ramos, B de Pascual-Teresa
Journal of medicinal chemistry 57 (24), 10205-10219, 2014
952014
Progress towards water-soluble triazole-based selective MMP-2 inhibitors
B Fabre, K Filipiak, JM Zapico, N Díaz, RJ Carbajo, AK Schott, ...
Organic & Biomolecular Chemistry 11 (38), 6623-6641, 2013
392013
Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action
K Filipiak, M Hidalgo, JM Silvan, B Fabre, RJ Carbajo, A Pineda-Lucena, ...
Food & function 5 (2), 381-389, 2014
372014
The development of a versatile trifunctional scaffold for biological applications
V Vaněk, J Pícha, B Fabre, M Buděšínský, M Lepšík, J Jiráček
European Journal of Organic Chemistry 2015 (17), 3689-3701, 2015
272015
An integrated computational and experimental approach to gaining selectivity for MMP‐2 within the gelatinase subfamily
B Fabre, K Filipiak, N Díaz, JM Zapico, D Suárez, A Ramos, ...
ChemBioChem 15 (3), 399-412, 2014
272014
Synthesis and evaluation of a library of trifunctional scaffold-derived compounds as modulators of the insulin receptor
B Fabre, J Pícha, V Vanek, I Selicharova, M Chrudinova, M Collinsova, ...
ACS Combinatorial Science 18 (12), 710-722, 2016
242016
A CuAAC–hydrazone–CuAAC trifunctional scaffold for the solid-phase synthesis of trimodal compounds: possibilities and limitations
B Fabre, J Pícha, V Vaněk, M Buděšínský, J Jiráček
Molecules 20 (10), 19310-19329, 2015
162015
New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment
B Fabre, K Filipiak, C Coderch, JM Zapico, RJ Carbajo, AK Schott, ...
RSC advances 4 (34), 17726-17735, 2014
112014
Tri‐Orthogonal Scaffolds for the Solid‐Phase Synthesis of Peptides
J Pícha, B Fabre, M Buděšínský, J Hajduch, M Abdellaoui, J Jiráček
European Journal of Organic Chemistry 2018 (37), 5180-5192, 2018
82018
Multipodal insulin mimetics built on adamantane or proline scaffolds
J Hajduch, B Fabre, B Klopp, R Pohl, M Buděšínský, V Šolínová, ...
Bioorganic chemistry 107, 104548, 2021
62021
Probing Tripodal peptide scaffolds as insulin and IGF‐1 receptor ligands
B Fabre, J Pícha, I Selicharová, L Žáková, M Chrudinová, J Hajduch, ...
European Journal of Organic Chemistry 2018 (37), 5193-5201, 2018
32018
Targeting the insulin receptor with hormone and peptide dimers
J Lin, I Selicharová, K Mitrová, B Fabre, VM Miriyala, M Lepšík, J Jiráček, ...
Journal of Peptide Science 29 (4), e3461, 2023
12023
Combinatorial libraries of bipodal binders of the insulin receptor
I Selicharová, B Fabre, M Soledad Garre Hernández, M Lubos, J Pícha, ...
ChemMedChem, e202400145, 2024
2024
Progress towards water-soluble triazole-based selective MMP-2 inhibitors.
A Ramos González, MP Martínez Alcázar, JM Zapico Rodríguez, ...
2013
Strategy to gain selectivity within the gelatinase subfamily. Design and synthesis of novel matrix metalloprotease-2 (mmp-2) inhibitors
B Fabre
Universidad CEU San Pablo, 2013
2013
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Artículos 1–15