Lucia Coppo
Lucia Coppo
Senior Researcher Karolinska Institute
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Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal
S Salzano, P Checconi, EM Hanschmann, CH Lillig, LD Bowler, P Chan, ...
Proceedings of the National Academy of Sciences 111 (33), 12157-12162, 2014
Hepatocyte hyperproliferation upon liver-specific co-disruption of thioredoxin-1, thioredoxin reductase-1, and glutathione reductase
JR Prigge, L Coppo, SS Martin, F Ogata, CG Miller, MD Bruschwein, ...
Cell reports 19 (13), 2771-2781, 2017
Nitric oxide protects against infection-induced neuroinflammation by preserving the stability of the blood-brain barrier
GC Olivera, X Ren, SK Vodnala, J Lu, L Coppo, C Leepiyasakulchai, ...
PLoS pathogens 12 (2), e1005442, 2016
Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury
V Branco, L Coppo, S Solá, J Lu, CMP Rodrigues, A Holmgren, ...
Redox biology 13, 278-287, 2017
Thiol regulation of pro-inflammatory cytokines and innate immunity: protein S-thiolation as a novel molecular mechanism
L Coppo, P Ghezzi
Biochemical Society Transactions 39 (5), 1268-1272, 2011
Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells
A Rodriguez-Garcia, D Hevia, JC Mayo, P Gonzalez-Menendez, L Coppo, ...
Redox biology 12, 634-647, 2017
Glutathione fine-tunes the innate immune response toward antiviral pathways in a macrophage cell line independently of its antioxidant properties
M Diotallevi, P Checconi, AT Palamara, I Celestino, L Coppo, A Holmgren, ...
Frontiers in immunology 8, 1239, 2017
In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways
R Priora, A Margaritis, S Frosali, L Coppo, D Summa, D Di Giuseppe, ...
Pharmacological Research 64 (3), 289-297, 2011
The role of protein sulfhydryl groups and protein disulfides of the platelet surface in aggregation processes involving thiol exchange reactions
A Margaritis, R Priora, S Frosali, D Di Giuseppe, D Summa, L Coppo, ...
Pharmacological research 63 (1), 77-84, 2011
Measurement of mixed disulfides including glutathionylated proteins
R Priora, L Coppo, S Salzano, P Di Simplicio, P Ghezzi
Methods in enzymology 473, 149-159, 2010
Determination of glutaredoxin enzyme activity and protein S-glutathionylation using fluorescent eosin-glutathione
L Coppo, SJ Montano, AC Padilla, A Holmgren
Analytical biochemistry 499, 24-33, 2016
The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of diamide-treated rats
R Priora, L Coppo, A Margaritis, D Di Giuseppe, S Frosali, D Summa, ...
Toxicology and applied pharmacology 242 (3), 333-343, 2010
The combination of ascorbate and menadione causes cancer cell death by oxidative stress and replicative stress
X Ren, SM Santhosh, L Coppo, FT Ogata, J Lu, A Holmgren
Free Radical Biology and Medicine 134, 350-358, 2019
Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246
L Haffo, J Lu, VJN Bykov, SS Martin, X Ren, L Coppo, KG Wiman, ...
Scientific reports 8 (1), 1-10, 2018
The control of hyperhomocysteinemia through thiol exchange mechanisms by mesna
D Di Giuseppe, R Priora, L Coppo, M Ulivelli, S Bartalini, D Summa, ...
Amino acids 46 (2), 429-439, 2014
Homocysteinemia control by cysteine in cerebral vascular patients after methionine loading test: evidences in physiological and pathological conditions in cerebro-vascular and …
M Ulivelli, R Priora, D Di Giuseppe, L Coppo, D Summa, A Margaritis, ...
Amino acids 48 (6), 1477-1489, 2016
Glutathione-glutaredoxin is an efficient electron donor system for mammalian p53R2–R1-dependent ribonucleotide reductase
R Sengupta, L Coppo, P Mishra, A Holmgren
Journal of Biological Chemistry 294 (34), 12708-12716, 2019
Enzymatic glutaredoxin-dependent method to determine glutathione and protein S-glutathionylation using fluorescent eosin-glutathione
L Coppo, FT Ogata, SM Santhosh, T Sventelius, A Holmgren
Analytical biochemistry 568, 24-30, 2019
Quantification of Global Protein Disulfides and Thiol-Protein Mixed Disulfides to Study the Protein Dethiolation Mechanisms
L Coppo, R Priora, S Salzano, P Ghezzi, P Di Simplicio
American Journal of Analytical Chemistry 2013, 2013
Inhibition of Thioredoxin Reductase by Triosmium Carbonyl Clusters
WX Koh, L Coppo, A Holmgren, JW Kong, WK Leong
Chemical Research in Toxicology, 2020
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