| Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal S Salzano, P Checconi, EM Hanschmann, CH Lillig, LD Bowler, P Chan, ... Proceedings of the National Academy of Sciences 111 (33), 12157-12162, 2014 | 376 | 2014 |
| Glutathione fine-tunes the innate immune response toward antiviral pathways in a macrophage cell line independently of its antioxidant properties M Diotallevi, P Checconi, AT Palamara, I Celestino, L Coppo, A Holmgren, ... Frontiers in immunology 8, 289507, 2017 | 88 | 2017 |
| Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury V Branco, L Coppo, S Solá, J Lu, CMP Rodrigues, A Holmgren, ... Redox biology 13, 278-287, 2017 | 72 | 2017 |
| Glutaredoxin: Discovery, redox defense and much more FT Ogata, V Branco, FF Vale, L Coppo Redox biology 43, 101975, 2021 | 70 | 2021 |
| Hepatocyte hyperproliferation upon liver-specific co-disruption of thioredoxin-1, thioredoxin reductase-1, and glutathione reductase JR Prigge, L Coppo, SS Martin, F Ogata, CG Miller, MD Bruschwein, ... Cell reports 19 (13), 2771-2781, 2017 | 66 | 2017 |
| Nitric oxide protects against infection-induced neuroinflammation by preserving the stability of the blood-brain barrier GC Olivera, X Ren, SK Vodnala, J Lu, L Coppo, C Leepiyasakulchai, ... PLoS pathogens 12 (2), e1005442, 2016 | 62 | 2016 |
| Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246 L Haffo, J Lu, VJN Bykov, SS Martin, X Ren, L Coppo, KG Wiman, ... Scientific reports 8 (1), 12671, 2018 | 58 | 2018 |
| Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells A Rodriguez-Garcia, D Hevia, JC Mayo, P Gonzalez-Menendez, L Coppo, ... Redox biology 12, 634-647, 2017 | 54 | 2017 |
| The combination of ascorbate and menadione causes cancer cell death by oxidative stress and replicative stress X Ren, SM Santhosh, L Coppo, FT Ogata, J Lu, A Holmgren Free Radical Biology and Medicine 134, 350-358, 2019 | 53 | 2019 |
| Thiol regulation of pro-inflammatory cytokines and innate immunity: protein S-thiolation as a novel molecular mechanism L Coppo, P Ghezzi Biochemical Society Transactions 39 (5), 1268-1272, 2011 | 35 | 2011 |
| The role of protein sulfhydryl groups and protein disulfides of the platelet surface in aggregation processes involving thiol exchange reactions A Margaritis, R Priora, S Frosali, D Di Giuseppe, D Summa, L Coppo, ... Pharmacological Research 63 (1), 77-84, 2011 | 30 | 2011 |
| Glutathione-glutaredoxin is an efficient electron donor system for mammalian p53R2–R1-dependent ribonucleotide reductase R Sengupta, L Coppo, P Mishra, A Holmgren Journal of Biological Chemistry 294 (34), 12708-12716, 2019 | 25 | 2019 |
| In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways R Priora, A Margaritis, S Frosali, L Coppo, D Summa, D Di Giuseppe, ... Pharmacological research 64 (3), 289-297, 2011 | 25 | 2011 |
| Measurement of mixed disulfides including glutathionylated proteins R Priora, L Coppo, S Salzano, P Di Simplicio, P Ghezzi Methods in enzymology 473, 149-159, 2010 | 23 | 2010 |
| Determination of glutaredoxin enzyme activity and protein S-glutathionylation using fluorescent eosin-glutathione L Coppo, SJ Montano, AC Padilla, A Holmgren Analytical biochemistry 499, 24-33, 2016 | 19 | 2016 |
| Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice V Scalcon, A Folda, MG Lupo, F Tonolo, N Pei, I Battisti, N Ferri, ... Redox Biology 51, 102277, 2022 | 16 | 2022 |
| The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of diamide-treated rats R Priora, L Coppo, A Margaritis, D Di Giuseppe, S Frosali, D Summa, ... Toxicology and applied pharmacology 242 (3), 333-343, 2010 | 15 | 2010 |
| Thiol-based antioxidants and the epithelial/mesenchymal transition in cancer FT Ogata, AY Simões Sato, L Coppo, RJ Arai, AI Stern, ... Antioxidants & Redox Signaling 36 (13), 1037-1050, 2022 | 10 | 2022 |
| N-Acetylcysteine or Sodium Selenite Prevent the p38-Mediated Production of Proinflammatory Cytokines by Microglia during Exposure to Mercury (II) V Branco, L Coppo, M Aschner, C Carvalho Toxics 10 (8), 433, 2022 | 9 | 2022 |
| The control of hyperhomocysteinemia through thiol exchange mechanisms by mesna D Di Giuseppe, R Priora, L Coppo, M Ulivelli, S Bartalini, D Summa, ... Amino acids 46, 429-439, 2014 | 8 | 2014 |
