Brian M. Baker
Brian M. Baker
Department of Chemistry & Biochemistry, University of Notre Dame
Verified email at nd.edu - Homepage
Title
Cited by
Cited by
Year
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical
YH Ding, BM Baker, DN Garboczi, WE Biddison, DC Wiley
Immunity 11 (1), 45-56, 1999
4101999
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry
BM Baker, KP Murphy
Biophysical journal 71 (4), 2049-2055, 1996
3601996
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity
F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ...
Journal of Experimental Medicine 211 (11), 2231-2248, 2014
2492014
Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase
BM Baker, KP Murphy
Journal of molecular biology 268 (2), 557-569, 1997
1841997
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ...
Immunity 31 (6), 885-896, 2009
1812009
The structure and stability of an HLA-A* 0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site
AR Khan, BM Baker, P Ghosh, WE Biddison, DC Wiley
The Journal of Immunology 164 (12), 6398, 2000
1752000
Prediction of binding energetics from structure using empirical parameterization
BM Baker, KP Murphy
Methods in enzymology 295, 294-315, 1998
1681998
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling
BM Baker, SJ Gagnon, WE Biddison, DC Wiley
Immunity 13 (4), 475-484, 2000
1562000
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes
KM Armstrong, KH Piepenbrink, BM Baker
Biochemical Journal 415 (Pt 2), 183, 2008
1372008
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance
Z Yu, MR Theoret, CE Touloukian, DR Surman, SC Garman, ...
Journal of Clinical Investigation 114, 551-559, 2004
1322004
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms
OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker
The Journal of Immunology 187 (5), 2453-2463, 2011
1252011
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design
OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker
The Journal of Immunology 174 (8), 4812, 2005
1202005
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand
RL Davis-Harrison, KM Armstrong, BM Baker
Journal of molecular biology 346 (2), 533-550, 2005
1122005
Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by …
BM Baker, RV Turner, SJ Gagnon, DC Wiley, WE Biddison
The Journal of experimental medicine 193 (5), 551, 2001
932001
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior
ES Folker, BM Baker, HV Goodson
Molecular biology of the cell 16 (11), 5373-5384, 2005
922005
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity
JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ...
Nature immunology, 2015
882015
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition
OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ...
Journal of molecular biology 372 (5), 1123-1136, 2007
862007
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics
OY Borbulevych, KH Piepenbrink, BM Baker
The Journal of Immunology 186 (5), 2950, 2011
742011
Thermodynamics of T‐cell receptor–peptide/MHC interactions: progress and opportunities
KM Armstrong, FK Insaidoo, BM Baker
Journal of Molecular Recognition 21 (4), 275-287, 2008
732008
T Cell Receptor Recognition< i> via</i> Cooperative Conformational Plasticity
SJ Gagnon, OY Borbulevych, RL Davis-Harrison, RV Turner, M Damirjian, ...
Journal of molecular biology 363 (1), 228-243, 2006
732006
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