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Yang Hai
Yang Hai
Assistant Professor, Department of Chemistry and Biochemistry, UCSB
Dirección de correo verificada de chem.ucsb.edu - Página principal
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Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
Y Hai, D Christianson
Nature Chemical Biology 12 (September), 741-747, 2016
4192016
ARID1A-mutated ovarian cancers depend on HDAC6 activity
W Bitler, B.G., Wu, S., Park, P.H., Hai, Y., Aird, K.M., Wang, Y., Zhai, Y ...
Nature Cell Biology, 2017
2112017
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Y Hai, SA Shinsky, NJ Porter, DW Christianson
Nature Communications 8, 15368, 2017
1692017
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis.
TY Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN
Nature 549 (7673), 502-506, 2017
1652017
Luminescent zinc salen complexes as single and two-photon fluorescence subcellular imaging probes
Y Hai, J-J Chen, P Zhao, H Lv, Y Yu, P Xu, and J-L Zhang
Chemical Communications 47, 2435-2437, 2011
1222011
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections
EL D'Antonio, B Ullman, SC Roberts, UG Dixit, ME Wilson, ...
Arch. Biochem. Biophys 535 (2), 163-176, 2013
862013
Rational design of ZnSalen as a single and two photon activatable fluorophore in living cells
J Jing, JJ Chen, Y Hai, J Zhan, P Xu, JL Zhang
Chemical Science 3, 3313-3320, 2012
612012
Genome mining of alkaloidal terpenoids from a hybrid terpene and nonribosomal peptide biosynthetic pathway
DA Yee, TB Kakule, W Cheng, M Chen, CTY Chong, Y Hai, LF Hang, ...
Journal of the American Chemical Society 142 (2), 710-714, 2019
462019
Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI
Y Cai, Y Hai, M Ohashi, CS Jamieson, M Garcia-Borras, KN Houk, J Zhou, ...
Nature chemistry 11 (9), 812-820, 2019
422019
Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids
Y Hai, M Chen, A Huang, Y Tang
J. Am. Chem. Soc., 2020
372020
Structural Basis for Aza-Glycine Stabilization of Collagen
AJ Kasznel, Y Zhang, Y Hai, D Chenoweth
Journal of the American Chemical Society, 2017
372017
Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi
Y Hai, AM Huang, Y Tang
Proceedings of the National Academy of Science, 2019
312019
A sensitive and quantitative autolysosome probe for detecting autophagic activity in live and prestained fixed cells
JJ Chen, J Jing, H Chang, Y Rong, Y Hai, J Tang, JL Zhang, P Xu
Autophagy 9, 894-904, 2013
312013
Molecular assembly directed by metal–aromatic interactions: control of the aggregation and photophysical properties of Zn–Salen complexes by aromatic mercuration
YB Cai, J Zhan, Y Hai, JL Zhang
Chem. Eur. J. 18, 4242-4249, 2012
282012
Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi
Y Hai, Y Tang
Journal of the American Chemical Society, 2018
262018
Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster
Y Hai, EJ Kerkhoven, MP Barrett, DW Christianson
Biochemistry 54 (2), 458-471, 2015
252015
Structure and function of non-native metal clusters in human arginase I.
ED D'Antonio, Y Hai, DW Christianson
Biochemistry 51 (42), 8399-8409, 2012
252012
Fungal siderophore biosynthesis catalysed by an iterative nonribosomal peptide synthetase
YT Y Hai, M Jenner
Chemical Science, 2020
222020
Complete Stereoinversion of l-Tryptophan by a Fungal Single-Module Nonribosomal Peptide Synthetase
Y Hai, M Jenner, Y Tang
Journal of the American Chemical Society 141 (41), 16222-16226, 2019
222019
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation
SS Gao, M Garcia-Borràs, JS Barber, Y Hai, A Duan, NK Garg, KN Houk, ...
Journal of the American Chemical Society, 2017
212017
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Artículos 1–20