Telomeres in cancer: tumour suppression and genome instability J Maciejowski, T de Lange Nature reviews Molecular cell biology 18 (3), 175-186, 2017 | 652 | 2017 |
Chromothripsis and kataegis induced by telomere crisis J Maciejowski, Y Li, N Bosco, PJ Campbell, T De Lange Cell 163 (7), 1641-1654, 2015 | 631 | 2015 |
Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling J Maciejowski, KA George, ME Terret, C Zhang, KM Shokat, PV Jallepalli Journal of Cell Biology 190 (1), 89-100, 2010 | 236 | 2010 |
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells ME Burkard, J Maciejowski, V Rodriguez-Bravo, M Repka, DM Lowery, ... PLoS biology 7 (5), e1000111, 2009 | 205 | 2009 |
Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor V Rodriguez-Bravo, J Maciejowski, J Corona, HK Buch, P Collin, ... Cell 156 (5), 1017-1031, 2014 | 177 | 2014 |
Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 170 | 2020 |
ER-directed TREX1 limits cGAS activation at micronuclei L Mohr, E Toufektchan, P von Morgen, K Chu, A Kapoor, J Maciejowski Molecular cell 81 (4), 724-738. e9, 2021 | 133 | 2021 |
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis J Maciejowski, A Chatzipli, A Dananberg, K Chu, E Toufektchan, ... Nature genetics 52 (9), 884-890, 2020 | 133 | 2020 |
cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing W Zhou, L Mohr, J Maciejowski, PJ Kranzusch Molecular cell 81 (4), 739-755. e7, 2021 | 117 | 2021 |
Mechanisms of APOBEC3 mutagenesis in human cancer cells M Petljak, A Dananberg, K Chu, EN Bergstrom, J Striepen, P von Morgen, ... Nature 607 (7920), 799-807, 2022 | 112 | 2022 |
Distinct roles of RZZ and Bub1-KNL1 in mitotic checkpoint signaling and kinetochore expansion JA Rodriguez-Rodriguez, C Lewis, KL McKinley, V Sikirzhytski, J Corona, ... Current Biology 28 (21), 3422-3429. e5, 2018 | 107 | 2018 |
A “latent niche” mechanism for tumor initiation M McGovern, R Voutev, J Maciejowski, AK Corsi, EJA Hubbard Proceedings of the National Academy of Sciences 106 (28), 11617-11622, 2009 | 100 | 2009 |
Mps1 regulates kinetochore-microtubule attachment stability via the Ska complex to ensure error-free chromosome segregation J Maciejowski, H Drechsler, K Grundner-Culemann, ER Ballister, ... Developmental cell 41 (2), 143-156. e6, 2017 | 80 | 2017 |
Quantitative analysis of germline mitosis in adult C. elegans J Maciejowski, N Ugel, B Mishra, M Isopi, EJA Hubbard Developmental biology 292 (1), 142-151, 2006 | 80 | 2006 |
Nuclear membrane rupture and its consequences J Maciejowski, EM Hatch Annual review of cell and developmental biology 36, 85-114, 2020 | 75 | 2020 |
Autosomal Genes of Autosomal/X-Linked Duplicated Gene Pairs and Germ-Line Proliferation in Caenorhabditis elegans J Maciejowski, JH Ahn, PG Cipriani, DJ Killian, AL Chaudhary, JI Lee, ... Genetics 169 (4), 1997-2011, 2005 | 63 | 2005 |
Nuclear envelope rupture is enhanced by loss of p53 or Rb Z Yang, J Maciejowski, T de Lange Molecular Cancer Research 15 (11), 1579-1586, 2017 | 55 | 2017 |
Molecular origins of APOBEC-associated mutations in cancer M Petljak, J Maciejowski DNA repair 94, 102905, 2020 | 54 | 2020 |
Epigenetic dysregulation from chromosomal transit in micronuclei AS Agustinus, D Al-Rawi, B Dameracharla, R Raviram, BSCL Jones, ... Nature 619 (7968), 176-183, 2023 | 34 | 2023 |
Genotoxic stress and viral infection induce transient expression of APOBEC3A and pro-inflammatory genes through two distinct pathways S Oh, E Bournique, D Bowen, P Jalili, A Sanchez, I Ward, A Dananberg, ... Nature communications 12 (1), 4917, 2021 | 31 | 2021 |