Follow
Thomas A Macek
Thomas A Macek
Other namesTA Macek, Thomas Macek, T Macek
Global Program Clinical Head, Neurosciences, Novartis
Verified email at novartis.com
Title
Cited by
Cited by
Year
Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy in patients with two copies of SMN2 (STR1VE): an open-label, single-arm …
JW Day, RS Finkel, CA Chiriboga, AM Connolly, TO Crawford, BT Darras, ...
The Lancet Neurology 20 (4), 284-293, 2021
3042021
A 3‐week, randomized, placebo‐controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states
RS McIntyre, M Cohen, J Zhao, L Alphs, TA Macek, J Panagides
Bipolar disorders 11 (7), 673-686, 2009
2492009
Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial
RS McIntyre, M Cohen, J Zhao, L Alphs, TA Macek, J Panagides
Journal of affective disorders 122 (1-2), 27-38, 2010
2112010
Differential involvement of group II and group III mGluRs as autoreceptors at lateral and medial perforant path synapses
TA Macek, DG Winder, RW Gereau 4th, CO Ladd, PJ Conn
Journal of neurophysiology 76 (6), 3798-3806, 1996
2091996
Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group
EM Wickwire, SG Williams, T Roth, VF Capaldi, M Jaffe, M Moline, ...
Neurotherapeutics 13 (2), 403-417, 2016
1552016
Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins
TA Macek, H Schaffhauser, PJ Conn
Journal of Neuroscience 18 (16), 6138-6146, 1998
1511998
Asenapine versus olanzapine in acute mania: a double‐blind extension study
RS McIntyre, M Cohen, J Zhao, L Alphs, TA Macek, J Panagides
Bipolar disorders 11 (8), 815-826, 2009
1472009
Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: the Phase III SPR1NT trial
KA Strauss, MA Farrar, F Muntoni, K Saito, JR Mendell, L Servais, ...
Nature medicine 28 (7), 1381-1389, 2022
1412022
Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study
RS McIntyre, M Cohen, J Zhao, L Alphs, TA Macek, J Panagides
Journal of affective disorders 126 (3), 358-365, 2010
1402010
Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study
RS McIntyre, M Cohen, J Zhao, L Alphs, TA Macek, J Panagides
Journal of affective disorders 126 (3), 358-365, 2010
1402010
Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: the Phase III SPR1NT trial
KA Strauss, MA Farrar, F Muntoni, K Saito, JR Mendell, L Servais, ...
Nature medicine 28 (7), 1390-1397, 2022
1152022
A phase I study of the oral combination of CI-994, a putative histone deacetylase inhibitor, and capecitabine
SD Undevia, HL Kindler, L Janisch, SC Olson, RL Schilsky, NJ Vogelzang, ...
Annals of oncology 15 (11), 1705-1711, 2004
842004
cAMP-dependent protein kinase inhibits mGluR2 coupling to G-proteins by direct receptor phosphorylation
H Schaffhauser, Z Cai, F Hubalek, TA Macek, J Pohl, TJ Murphy, PJ Conn
Journal of Neuroscience 20 (15), 5663-5670, 2000
792000
Dissociation of protein kinase-mediated regulation of metabotropic glutamate receptor 7 (mGluR7) interactions with calmodulin and regulation of mGluR7 function
SD Sorensen, TA Macek, Z Cai, JA Saugstad, PJ Conn
Molecular pharmacology 61 (6), 1303-1312, 2002
462002
A phase 2, randomized, placebo-controlled study of the efficacy and safety of TAK-063 in subjects with an acute exacerbation of schizophrenia
TA Macek, M McCue, X Dong, E Hanson, P Goldsmith, J Affinito, ...
Schizophrenia research 204, 289-294, 2019
362019
A human [11C] T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor
A Takano, P Stenkrona, V Stepanov, N Amini, S Martinsson, M Tsai, ...
Neuroimage 141, 10-17, 2016
282016
Activation of PKC disrupts presynaptic inhibition by group II and group III metabotropic glutamate receptors and uncouples the receptor from GTP‐binding proteins
TA Macek, H Schaffhauser, PJ Conn
Annals of the New York Academy of Sciences 868 (1), 554-557, 1999
261999
Efficacy and safety of sublingual ramelteon as an adjunctive therapy in the maintenance treatment of bipolar I disorder in adults: a phase 3, randomized controlled trial
AR Mahableshwarkar, JR Calabrese, TA Macek, K Budur, A Adefuye, ...
Journal of affective disorders 221, 275-282, 2017
232017
Onasemnogene Abeparvovec gene therapy in presymptomatic spinal muscular atrophy (SMA): SPR1NT study update in children with 2 copies of SMN2 (4190)
K Strauss, F Muntoni, M Farrar, K Saito, J Mendell, L Servais, H McMillan, ...
Neurology 96 (15 Supplement), 2021
212021
Onasemnogene abeparvovec-xioi gene-replacement therapy for spinal muscular atrophy type 1 (SMA1): phase 3 US study (STR1VE) update (1828)
JW Day, CA Chiriboga, TO Crawford, BT Darras, RS Finkel, AM Connolly, ...
Neurology 94 (15 Supplement), 2020
212020
The system can't perform the operation now. Try again later.
Articles 1–20