Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice E Beli, Y Yan, L Moldovan, CP Vieira, R Gao, Y Duan, R Prasad, ... Diabetes 67 (9), 1867-1879, 2018 | 288 | 2018 |
SGLT2 protein expression is increased in human diabetic nephropathy: SGLT2 protein inhibition decreases renal lipid accumulation, inflammation, and the development of … XX Wang, J Levi, Y Luo, K Myakala, M Herman-Edelstein, L Qiu, D Wang, ... Journal of Biological Chemistry 292 (13), 5335-5348, 2017 | 280 | 2017 |
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease RH McMahan, XX Wang, LL Cheng, T Krisko, M Smith, K El Kasmi, ... Journal of Biological Chemistry 288 (17), 11761-11770, 2013 | 235 | 2013 |
Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy T Jiang, XX Wang, P Scherzer, P Wilson, J Tallman, H Takahashi, J Li, ... Diabetes 56 (10), 2485-2493, 2007 | 234 | 2007 |
Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist G Rizzo, D Passeri, F De Franco, G Ciaccioli, L Donadio, G Rizzo, ... Molecular pharmacology 78 (4), 617-630, 2010 | 211 | 2010 |
Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model XX Wang, T Jiang, Y Shen, Y Caldas, S Miyazaki-Anzai, H Santamaria, ... Diabetes 59 (11), 2916-2927, 2010 | 191 | 2010 |
The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria XX Wang, T Jiang, Y Shen, L Adorini, M Pruzanski, FJ Gonzalez, ... American Journal of Physiology-Renal Physiology 297 (6), F1587-F1596, 2009 | 175 | 2009 |
G protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes XX Wang, MH Edelstein, U Gafter, L Qiu, Y Luo, E Dobrinskikh, S Lucia, ... Journal of the American Society of Nephrology 27 (5), 1362-1378, 2016 | 168 | 2016 |
Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate H Giral, Y Caldas, E Sutherland, P Wilson, S Breusegem, N Barry, ... American Journal of Physiology-Renal Physiology 297 (5), F1466-F1475, 2009 | 168 | 2009 |
FXR/TGR5 dual agonist prevents progression of nephropathy in diabetes and obesity XX Wang, D Wang, Y Luo, K Myakala, E Dobrinskikh, AZ Rosenberg, ... Journal of the American Society of Nephrology 29 (1), 118-137, 2018 | 151 | 2018 |
PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone L Laurino, XX Wang, BA de la Houssaye, L Sosa, S Dupraz, A Cáceres, ... Journal of Cell Science 118 (16), 3653-3662, 2005 | 138 | 2005 |
Regulation of membrane expansion at the nerve growth cone KH Pfenninger, L Laurino, D Peretti, X Wang, S Rosso, G Morfini, ... Journal of cell science 116 (7), 1209-1217, 2003 | 115 | 2003 |
Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism XX Wang, T Jiang, Y Shen, H Santamaria, N Solis, C Arbeeny, M Levi American Journal of Physiology-Renal Physiology 300 (3), F801-F810, 2011 | 113 | 2011 |
Spaceflight activates lipotoxic pathways in mouse liver KR Jonscher, A Alfonso-Garcia, JL Suhalim, DJ Orlicky, EO Potma, ... PloS one 11 (4), e0152877, 2016 | 91 | 2016 |
The sodium-glucose cotransporter 2 inhibitor dapagliflozin prevents renal and liver disease in western diet induced obesity mice D Wang, Y Luo, X Wang, DJ Orlicky, K Myakala, P Yang, M Levi International journal of molecular sciences 19 (1), 137, 2018 | 90 | 2018 |
Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency SY Breusegem, H Takahashi, H Giral-Arnal, X Wang, T Jiang, ... American Journal of Physiology-Renal Physiology 297 (2), F350-F361, 2009 | 89 | 2009 |
Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes S Hazra, A Rasheed, A Bhatwadekar, X Wang, LC Shaw, M Patel, ... Diabetes 61 (12), 3270-3279, 2012 | 77 | 2012 |
A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice XX Wang, Y Luo, D Wang, L Adorini, M Pruzanski, E Dobrinskikh, M Levi Journal of Biological Chemistry 292 (29), 12018-12024, 2017 | 63 | 2017 |
Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice KR Jonscher, MS Stewart, A Alfonso-Garcia, BC DeFelice, XX Wang, ... The FASEB Journal 31 (4), 1434, 2017 | 56 | 2017 |
The mechanism of diabetic retinopathy pathogenesis unifying key lipid regulators, sirtuin 1 and liver X receptor SS Hammer, E Beli, N Kady, Q Wang, K Wood, TA Lydic, G Malek, ... EBioMedicine 22, 181-190, 2017 | 54 | 2017 |