Saswata Talukdar
Saswata Talukdar
CardioMetabolic diseases, Merck Research Labs - South San Francisco
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GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
DY Oh, S Talukdar, EJ Bae, T Imamura, H Morinaga, WQ Fan, P Li, WJ Lu, ...
Cell 142 (5), 687-698, 2010
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
S Talukdar, G Bandyopadhyay, D Li, J Xu, J McNelis, M Lu, P Li, Q Yan, ...
Nature medicine 18 (9), 1407-1412, 2012
Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet–Induced Insulin Resistance
YS Lee, P Li, JY Huh, IJ Hwang, M Lu, JI Kim, M Ham, S Talukdar, A Chen, ...
Diabetes 60 (10), 2474-2483, 2011
Increased macrophage migration into adipose tissue in obese mice
H Morinaga, S Talukdar, EJ Bae, JM Olefsky
Diabetes 61 (2), 346-354, 2012
Brain PPAR-[gamma] promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones
M Lu, DA Sarruf, S Talukdar, S Sharma, P Li, G Bandyopadhyay, ...
Nature medicine 17 (5), 618-622, 2011
Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
P Li, WQ Fan, J Xu, M Lu, H Yamamoto, J Auwerx, DD Sears, S Talukdar, ...
Cell 147 (4), 815-826, 2011
Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases
S Talukdar, JM Olefsky, O Osborn
Trends in pharmacological sciences 32 (9), 543-550, 2011
A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects
S Talukdar, Y Zhou, D Li, M Rossulek, J Dong, V Somayaji, Y Weng, ...
Cell metabolism 23 (3), 427-440, 2016
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3
JH Lee, AV Budanov, S Talukdar, EJ Park, HL Park, HW Park, ...
Cell metabolism 16 (3), 311-321, 2012
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
P Li, G Bandyopadhyay, WS Lagakos, S Talukdar, O Osborn, A Johnson, ...
Nature medicine 21 (3), 239-247, 2015
FGF21 regulates sweet and alcohol preference
S Talukdar, BM Owen, P Song, G Hernandez, Y Zhang, Y Zhou, WT Scott, ...
Cell metabolism 23 (2), 344-349, 2016
The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
S Talukdar, FB Hillgartner
Journal of lipid research 47 (11), 2451, 2006
FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
LS Christian Schlein, Saswata Talukdar, Markus Heine, Alexander W. Fischer ...
Cell Metabolism, 2016
NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids
P Li, NJ Spann, MU Kaikkonen, M Lu, JN Fox, G Bandyopadhyay, ...
Cell 155 (1), 200-214, 2013
Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice
J Chapman, PD Miles, JM Ofrecio, JG Neels, GY Joseph, JL Resnik, ...
PloS one 5 (11), e13959, 2010
Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody
J Huang, T Ishino, G Chen, P Rolzin, TF Osothprarop, K Retting, L Li, ...
Journal of Pharmacology and Experimental Therapeutics 346 (2), 270-280, 2013
Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues
M Lu, DA Sarruf, P Li, O Osborn, M Sanchez-Alavez, S Talukdar, A Chen, ...
Journal of Biological Chemistry 288 (15), 10722-10735, 2013
GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity
J Xu, H Morinaga, D Oh, P Li, A Chen, S Talukdar, E Lazarowski, ...
The Journal of Immunology 189 (4), 1992-1999, 2012
G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice
O Osborn, J McNelis, M Sanchez-Alavez, S Talukdar, M Lu, PP Li, ...
The Journal of clinical investigation 122 (7), 2444-2453, 2012
Once‐weekly administration of a long‐acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese …
AM Kim, VR Somayaji, JQ Dong, TP Rolph, Y Weng, JR Chabot, ...
Diabetes, Obesity and Metabolism 19 (12), 1762-1772, 2017
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