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Andreas Bader
Andreas Bader
Triumvira Immunologics
Dirección de correo verificada de triumvira.com
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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
C Liu, K Kelnar, B Liu, X Chen, T Calhoun-Davis, H Li, L Patrawala, H Yan, ...
Nature medicine 17 (2), 211-215, 2011
16242011
Oncogenic PI3K deregulates transcription and translation
AG Bader, S Kang, L Zhao, PK Vogt
Nature Reviews Cancer 5 (12), 921-929, 2005
10752005
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
S Kang, AG Bader, PK Vogt
Proceedings of the National Academy of Sciences 102 (3), 802-807, 2005
10222005
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
JF Wiggins, L Ruffino, K Kelnar, M Omotola, L Patrawala, D Brown, ...
Cancer research 70 (14), 5923-5930, 2010
8102010
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
P Trang, JF Wiggins, CL Daige, C Cho, M Omotola, D Brown, ...
Molecular Therapy 19 (6), 1116-1122, 2011
8032011
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors
MS Beg, AJ Brenner, J Sachdev, M Borad, YK Kang, J Stoudemire, ...
Investigational new drugs 35, 180-188, 2017
7972017
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
A Esquela-Kerscher, P Trang, JF Wiggins, L Patrawala, A Cheng, L Ford, ...
Cell cycle 7 (6), 759-764, 2008
7862008
miR-34–a microRNA replacement therapy is headed to the clinic
AG Bader
Frontiers in genetics 3, 28826, 2012
7682012
The promise of microRNA replacement therapy
AG Bader, D Brown, M Winkler
Cancer research 70 (18), 7027-7030, 2010
7442010
Regression of murine lung tumors by the let-7 microRNA
P Trang, PP Medina, JF Wiggins, L Ruffino, K Kelnar, M Omotola, ...
Oncogene 29 (11), 1580-1587, 2010
6222010
PDL1 Regulation by p53 via miR-34
MA Cortez, C Ivan, D Valdecanas, X Wang, HJ Peltier, Y Ye, L Araujo, ...
Journal of the National Cancer Institute 108 (1), djv303, 2016
6012016
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
DS Hong, YK Kang, M Borad, J Sachdev, S Ejadi, HY Lim, AJ Brenner, ...
British journal of cancer 122 (11), 1630-1637, 2020
5622020
Cancer-specific mutations in PIK3CA are oncogenic in vivo
AG Bader, S Kang, PK Vogt
Proceedings of the National Academy of Sciences 103 (5), 1475-1479, 2006
5292006
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
F Takeshita, L Patrawala, M Osaki, R Takahashi, Y Yamamoto, N Kosaka, ...
Molecular Therapy 18 (1), 181-187, 2010
5102010
Developing therapeutic microRNAs for cancer
AG Bader, D Brown, J Stoudemire, P Lammers
Gene therapy 18 (12), 1121-1126, 2011
4102011
A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer
AL Kasinski, K Kelnar, C Stahlhut, E Orellana, J Zhao, E Shimer, S Dysart, ...
Oncogene 34 (27), 3547-3555, 2015
2362015
Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer
MA Cortez, D Valdecanas, X Zhang, Y Zhan, V Bhardwaj, GA Calin, ...
Molecular Therapy 22 (8), 1494-1503, 2014
2182014
Phosphatidylinositol 3-kinase: the oncoprotein
PK Vogt, JR Hart, M Gymnopoulos, H Jiang, S Kang, AG Bader, L Zhao, ...
Phosphoinositide 3-kinase in Health and Disease: Volume 2, 79-104, 2011
1692011
Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo
VJ Craig, A Tzankov, M Flori, CA Schmid, AG Bader, A Müller
Leukemia 26 (11), 2421-2424, 2012
1322012
Inhibition of protein synthesis by Y box-binding protein 1 blocks oncogenic cell transformation
AG Bader, PK Vogt
Molecular and cellular biology, 2005
1312005
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Artículos 1–20