Human TRPA1 is intrinsically cold-and chemosensitive with and without its N-terminal ankyrin repeat domain L Moparthi, S Survery, M Kreir, C Simonsen, P Kjellbom, ED Högestätt, ... Proceedings of the National Academy of Sciences 111 (47), 16901-16906, 2014 | 165 | 2014 |
Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes M Kreir, C Farre, M Beckler, M George, N Fertig Lab on a Chip 8 (4), 587-595, 2008 | 128 | 2008 |
Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level KR Mahendran, M Kreir, H Weingart, N Fertig, M Winterhalter Journal of biomolecular Screening 15 (3), 302-307, 2010 | 121 | 2010 |
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins D Shaya, M Kreir, RA Robbins, S Wong, J Hammon, A Brüggemann, ... Proceedings of the National Academy of Sciences 108 (30), 12313-12318, 2011 | 98 | 2011 |
Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology C Farre, A Haythornthwaite, C Haarmann, S Stoelzle, M Kreir, M George, ... Combinatorial chemistry & high throughput screening 12 (1), 24-37, 2009 | 80 | 2009 |
The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics E Sancho-Vaello, D Gil-Carton, P François, EJ Bonetti, M Kreir, ... Scientific reports 10 (1), 17356, 2020 | 69 | 2020 |
Natural and artificial ion channels for biosensing platforms L Steller, M Kreir, R Salzer Analytical and bioanalytical chemistry 402, 209-230, 2012 | 63 | 2012 |
Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule‐associated protein TAU mutations which displays several phenotypes … JA García‐León, A Cabrera‐Socorro, K Eggermont, A Swijsen, J Terryn, ... Alzheimer's & Dementia 14 (10), 1261-1280, 2018 | 52 | 2018 |
Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans? M Kreir, B Van Deuren, S Versweyveld, A De Bondt, I Van den Wyngaert, ... Toxicology and Applied Pharmacology 346, 45-57, 2018 | 48 | 2018 |
Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system SK Dondapati, M Kreir, RB Quast, DA Wüstenhagen, A Brüggemann, ... Biosensors and Bioelectronics 59, 174-183, 2014 | 48 | 2014 |
Planar patch clamp: advances in electrophysiology A Brüggemann, C Farre, C Haarmann, A Haythornthwaite, M Kreir, ... Potassium Channels: Methods and Protocols, 165-176, 2009 | 48 | 2009 |
Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial peptide ion channel H Itoh, S Matsuoka, M Kreir, M Inoue Journal of the American Chemical Society 134 (34), 14011-14018, 2012 | 33 | 2012 |
The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes O Gaßmann, M Kreir, C Ambrosi, J Pranskevich, A Oshima, C Röling, ... Journal of structural biology 168 (1), 168-176, 2009 | 33 | 2009 |
SOX9-induced generation of functional astrocytes supporting neuronal maturation in an all-human system K Neyrinck, J Van Den Daele, T Vervliet, J De Smedt, K Wierda, M Nijs, ... Stem Cell Reviews and Reports 17 (5), 1855-1873, 2021 | 23 | 2021 |
Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms C Weichbrodt, H Bajaj, G Baaken, J Wang, S Guinot, M Kreir, ... Analyst 140 (14), 4874-4881, 2015 | 22 | 2015 |
Green fluorescent protein changes the conductance of connexin 43 (Cx43) hemichannels reconstituted in planar lipid bilayers C Carnarius, M Kreir, M Krick, C Methfessel, V Moehrle, O Valerius, ... Journal of Biological Chemistry 287 (4), 2877-2886, 2012 | 22 | 2012 |
Role of Kv7. 2/Kv7. 3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons M Kreir, A De Bondt, I Van den Wyngaert, G Teuns, HR Lu, DJ Gallacher European Journal of Pharmacology 858, 172474, 2019 | 15 | 2019 |
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies PY Shih, M Kreir, D Kumar, F Seibt, F Pestana, B Schmid, B Holst, ... Stem Cell Research 54, 102386, 2021 | 12 | 2021 |
Functional characterization of p7 viroporin from hepatitis C virus produced in a cell-free expression system T Soranzo, S Cortès, F Gilde, M Kreir, C Picart, JL Lenormand Protein expression and purification 118, 83-91, 2016 | 11 | 2016 |
Cell-free expression of a functional pore-only sodium channel G Kovácsová, E Gustavsson, J Wang, M Kreir, S Peuker, S Westenhoff Protein Expression and Purification 111, 42-47, 2015 | 10 | 2015 |