CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting DG Courtney, JE Moore, SD Atkinson, E Maurizi, EHA Allen, DML Pedrioli, ... Gene therapy 23 (1), 108-112, 2016 | 131 | 2016 |
Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex SD Atkinson, VE McGilligan, H Liao, I Szeverenyi, FJD Smith, CBT Moore, ... Journal of investigative dermatology 131 (10), 2079-2086, 2011 | 94 | 2011 |
Perceptions of the impact of depression and anxiety and the medication for these conditions on safety in the workplace C Haslam, S Atkinson, S Brown, RA Haslam Occupational and environmental medicine 62 (8), 538-545, 2005 | 68 | 2005 |
Effect of tear hyperosmolarity and signs of clinical ocular surface pathology upon conjunctival goblet cell function in the human ocular surface JE Moore, GT Vasey, DA Dartt, VE McGilligan, SD Atkinson, C Grills, ... Investigative ophthalmology & visual science 52 (9), 6174-6180, 2011 | 65 | 2011 |
Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy EHA Allen, SD Atkinson, H Liao, JE Moore, DML Pedrioli, FJD Smith, ... Investigative ophthalmology & visual science 54 (1), 494-502, 2013 | 47 | 2013 |
Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I DG Courtney, SD Atkinson, JE Moore, E Maurizi, C Serafini, G Pellegrini, ... Investigative ophthalmology & visual science 55 (2), 977-985, 2014 | 46 | 2014 |
siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy DG Courtney, SD Atkinson, EHA Allen, JE Moore, CP Walsh, ... Investigative ophthalmology & visual science 55 (5), 3352-3360, 2014 | 39 | 2014 |
Effective in vivo topical delivery of siRNA and gene silencing in intact corneal epithelium using a modified cell-penetrating peptide D Schiroli, MJ Gómara, E Maurizi, SD Atkinson, L Mairs, KA Christie, ... Molecular Therapy-Nucleic Acids 17, 891-906, 2019 | 37 | 2019 |
Targeting the NLRP3 inflammasome in glaucoma S Coyle, MN Khan, M Chemaly, B Callaghan, C Doyle, CE Willoughby, ... Biomolecules 11 (8), 1239, 2021 | 31 | 2021 |
Protein composition of TGFBI-R124C-and TGFBI-R555W-associated aggregates suggests multiple mechanisms leading to lattice and granular corneal dystrophy DG Courtney, ET Poulsen, S Kennedy, JE Moore, SD Atkinson, E Maurizi, ... Investigative ophthalmology & visual science 56 (8), 4653-4661, 2015 | 30 | 2015 |
The TWEAK/Fn14/CD163 axis—implications for metabolic disease W Ratajczak, SD Atkinson, C Kelly Reviews in Endocrine and Metabolic Disorders 23 (3), 449-462, 2022 | 26 | 2022 |
Protection of corneal epithelial stem cells prevents ultraviolet A damage during corneal collagen cross-linking treatment for keratoconus JE Moore, SD Atkinson, DT Azar, J Worthington, CS Downes, ... British Journal of Ophthalmology 98 (2), 270-274, 2014 | 26 | 2014 |
P63 expression in conjunctival proliferative diseases: pterygium and laryngo-onycho-cutaneous (LOC) syndrome SD Atkinson, JE Moore, S Shah, A Sharma, RM Best, A Leccisotti, ... Current eye research 33 (7), 551-558, 2008 | 24 | 2008 |
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy EHA Allen, DG Courtney, SD Atkinson, JE Moore, L Mairs, ET Poulsen, ... Human molecular genetics 25 (6), 1176-1191, 2016 | 23 | 2016 |
A comparison of the clinical and molecular diagnosis of herpes simplex keratitis V McGilligan, JE Moore, M Tallouzi, SD Atkinson, H O'Neill, S Feeney, ... Open Journal of Ophthalmology 4 (3), 65-74, 2014 | 18 | 2014 |
A novel role for CRIM1 in the corneal response to UV and pterygium development E Maurizi, D Schiroli, SD Atkinson, L Mairs, DG Courtney, B O'Hagan, ... Experimental eye research 179, 75-92, 2019 | 13 | 2019 |
Genome-wide RNA sequencing of human trabecular meshwork cells treated with TGF-β1: relevance to pseudoexfoliation glaucoma AW Roodnat, B Callaghan, C Doyle, M Henry, K Goljanek-Whysall, ... Biomolecules 12 (11), 1693, 2022 | 11 | 2022 |
Coincidence versus consequence: opportunities in multi-morbidity research and inflammation as a pervasive feature DS Gibson, S Drain, C Kelly, V McGilligan, P McClean, SD Atkinson, ... Expert Review of Precision Medicine and Drug Development 2 (3), 147-156, 2017 | 6 | 2017 |
A20 controls expression of beta-cell regulatory genes and transcription factors W Ratajczak, SD Atkinson, C Kelly Journal of Molecular Endocrinology 67 (4), 189-201, 2021 | 5 | 2021 |
Thrombophilic-Type Placental Pathologies and Skeletal Growth Delay Following Maternal Administration of Angiostatin4.5 in Mice CS Rutland, SD Atkinson, M Mukhopadhyay, K Jiang, GA Soff, ... Biology of reproduction 84 (3), 505-513, 2011 | 3 | 2011 |