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Mahdi Golkaram
Mahdi Golkaram
SubChapter Bioinformatics Lead at Roche
Correu electrònic verificat a roche.com
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Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy
C Krishna, RG DiNatale, F Kuo, RM Srivastava, L Vuong, D Chowell, ...
Cancer cell 39 (5), 662-677. e6, 2021
2032021
Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
TJ Nowakowski*, N Rani*, M Golkaram*, HR Zhou* (*equal contribution), ...
Nature Neuroscience, 1, 2018
1452018
Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite
Y Zhang, C Huang, S Kim, M Golkaram, MWA Dixon, L Tilley, J Li, ...
Proceedings of the National Academy of Sciences 112 (19), 6068-6073, 2015
1262015
Atomic-scale insight into the interactions between hydroxyl radicals and DNA in solution using the ReaxFF reactive force field
CCW Verlackt, EC Neyts, T Jacob, D Fantauzzi, M Golkaram, YK Shin, ...
New Journal of Physics 17 (10), 103005, 2015
542015
Macromolecular crowding regulates the gene expression profile by limiting diffusion
M Golkaram, S Hellander, B Drawert, LR Petzold
PLoS computational biology 12 (11), e1005122, 2016
382016
Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape
M Golkaram, F Kuo, S Gupta, MI Carlo, ML Salmans, R Vijayaraghavan, ...
Genome Medicine 14 (1), 143, 2022
212022
HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome
M Golkaram, ML Salmans, S Kaplan, R Vijayaraghavan, M Martins, ...
NPJ genomic medicine 6 (1), 13, 2021
212021
The role of chromatin density in cell population heterogeneity during stem cell differentiation
M Golkaram, J Jang, S Hellander, KS Kosik, LR Petzold
Scientific reports 7 (1), 13307, 2017
182017
Revealing graphene oxide toxicity mechanisms: A reactive molecular dynamics study
M Golkaram, ACT van Duin
Materials discovery 1, 54-62, 2015
162015
Genetic and microenvironmental intra-tumor heterogeneity impacts colorectal cancer evolution and metastatic development
D Sobral, M Martins, S Kaplan, M Golkaram, M Salmans, N Khan, ...
Communications Biology 5 (1), 937, 2022
152022
Control over single-cell distribution of G1 lengths by WNT governs pluripotency
J Jang, D Han, M Golkaram, M Audouard, G Liu, D Bridges, S Hellander, ...
Plos Biology 17 (9), e3000453, 2019
142019
A targetable myeloid inflammatory state governs disease recurrence in clear-cell renal cell carcinoma
PM Rappold, L Vuong, J Leibold, NH Chakiryan, M Curry, F Kuo, E Sabio, ...
Cancer discovery 12 (10), 2308-2329, 2022
132022
Design and modeling of a novel translational and angular micro-electromechanical accelerometer
M Amereh, MM Aghdam, M Golkaram
Aerospace Science and Technology 50, 15-24, 2016
72016
Reactive molecular dynamics study of the pH-dependent dynamic structure of α-helix
M Golkaram, YK Shin, ACT Van Duin
The Journal of Physical Chemistry B 118 (47), 13498-13504, 2014
72014
Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma
C Valero*, M Golkaram*, JL Vos* (*equal contribution), B Xu, C Fitzgerald, ...
The Journal of Clinical Investigation, 2023
52023
Immunometabolic coevolution defines unique microenvironmental niches in ccRCC
C Tang, AX Xie, EM Liu, F Kuo, M Kim, RG DiNatale, M Golkaram, ...
Cell Metabolism 35 (8), 1424-1440. e5, 2023
52023
Identification of biomarkers predictive of metastasis development in early-stage colorectal cancer using network-based regularization
C Peixoto, MB Lopes, M Martins, S Casimiro, D Sobral, AR Grosso, ...
BMC bioinformatics 24 (1), 17, 2023
52023
Free transverse vibration analysis of thin rectangular plates locally suspended on elastic beam
M Golkaram, MM Aghdam
Proceedings of the Institution of Mechanical Engineers, Part C: Journal of …, 2013
52013
Novel Genetic Subtypes of Urothelial Carcinoma With Differential Outcomes on Immune Checkpoint Blockade
M Sarfaty*, M Golkaram* (*equal contribution), SA Funt, H Al-Ahmadie, ...
Journal of Clinical Oncology, JCO. 22.02144, 2023
42023
The interplay between cancer type, panel size and tumor mutational burden threshold in patient selection for cancer immunotherapy
M Golkaram, C Zhao, K Kruglyak, S Zhang, S Bilke
PLOS Computational Biology 16 (11), e1008332, 2020
42020
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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