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Juan C Vázquez-Ucha (ORCID 0000-0003-4949-0779)
Juan C Vázquez-Ucha (ORCID 0000-0003-4949-0779)
Researcher. Complexo Hospitalario Universitario A Coruña (CHUAC)- INIBIC
Dirección de correo verificada de sergas.es - Página principal
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New carbapenemase inhibitors: clearing the way for the β-lactams
JC Vázquez-Ucha, J Arca-Suárez, G Bou, A Beceiro
International Journal of Molecular Sciences 21 (23), 9308, 2020
832020
Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cells
L Álvarez-Fraga, A Pérez, S Rumbo-Feal, M Merino, JA Vallejo, ...
Virulence 7 (4), 443-455, 2016
582016
Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas …
J Arca-Suárez, C Lasarte-Monterrubio, BK Rodiño-Janeiro, G Cabot, ...
Journal of Antimicrobial Chemotherapy 76 (1), 91-100, 2021
392021
Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii
L Álvarez-Fraga, JC Vázquez-Ucha, M Martínez-Guitián, JA Vallejo, ...
Virulence 9 (1), 496-509, 2018
382018
Activity of the β-lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii
JC Vázquez-Ucha, M Maneiro, M Martínez-Guitián, J Buynak, CR Bethel, ...
Antimicrobial Agents and Chemotherapy 61 (11), 10.1128/aac. 01172-17, 2017
362017
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48
JA Vallejo, M Martinez-Guitian, JC Vázquez-Ucha, C González-Bello, ...
Journal of Antimicrobial Chemotherapy 71 (8), 2171-2180, 2016
362016
Activity of imipenem/relebactam against a Spanish nationwide collection of carbapenemase-producing Enterobacterales
JC Vázquez-Ucha, A Seoane-Estévez, BK Rodiño-Janeiro, ...
Journal of Antimicrobial Chemotherapy 76 (6), 1498-1510, 2021
312021
Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane/tazobactam during treatment of an MDR Pseudomonas aeruginosa infection
J Arca-Suárez, JC Vázquez-Ucha, PA Fraile-Ribot, E Lence, G Cabot, ...
Journal of Antimicrobial Chemotherapy 75 (11), 3209-3217, 2020
312020
Selection of AmpC β-lactamase variants and metallo-β-lactamases leading to ceftolozane/tazobactam and ceftazidime/avibactam resistance during treatment of MDR/XDR Pseudomonas …
A Ruedas-López, I Alonso-García, C Lasarte-Monterrubio, ...
Antimicrobial Agents and Chemotherapy 66 (2), e02067-21, 2022
292022
Assessment of activity and resistance mechanisms to cefepime in combination with the novel β-lactamase inhibitors zidebactam, taniborbactam, and enmetazobactam against a …
JC Vázquez-Ucha, C Lasarte-Monterrubio, P Guijarro-Sánchez, M Oviaño, ...
Antimicrobial Agents and Chemotherapy 66 (2), e01676-21, 2022
282022
In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa
D Pech-Puch, M Pérez-Povedano, M Martinez-Guitian, ...
Marine Drugs 18 (6), 326, 2020
272020
Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae ST-15
E Gato, JC Vázquez-Ucha, S Rumbo-Feal, L Álvarez-Fraga, JA Vallejo, ...
Proceedings of the National Academy of Sciences 117 (29), 17249-17259, 2020
252020
Challenging antimicrobial susceptibility and evolution of resistance (OXA-681) during treatment of a long-term nosocomial infection caused by a Pseudomonas aeruginosa ST175 clone
J Arca-Suárez, P Fraile-Ribot, JC Vázquez-Ucha, G Cabot, ...
Antimicrobial agents and chemotherapy 63 (10), 10.1128/aac. 01110-19, 2019
252019
Targeting the motion of shikimate kinase: development of competitive inhibitors that stabilize an inactive open conformation of the enzyme
V Prado, E Lence, M Maneiro, JC Vázquez-Ucha, A Beceiro, P Thompson, ...
Journal of Medicinal Chemistry 59 (11), 5471-5487, 2016
242016
Antisense inhibition of lpxB gene expression in Acinetobacter baumannii by peptide–PNA conjugates and synergy with colistin
M Martínez-Guitián, JC Vázquez-Ucha, L Álvarez-Fraga, K Conde-Pérez, ...
Journal of Antimicrobial Chemotherapy 75 (1), 51-59, 2020
222020
Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam-and ceftazidime/avibactam-resistant Pseudomonas …
C Lasarte-Monterrubio, PA Fraile-Ribot, JC Vázquez-Ucha, G Cabot, ...
Journal of Antimicrobial Chemotherapy 77 (10), 2809-2815, 2022
212022
Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens Acinetobacter baumannii and Klebsiella …
JC Vázquez-Ucha, M Martínez-Guitián, C Lasarte-Monterrubio, ...
Biomedicine & Pharmacotherapy 130, 110606, 2020
172020
Emergence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacterales in Spain studied by whole-genome sequencing
J Arca-Suárez, BK Rodiño-Janeiro, A Pérez, P Guijarro-Sánchez, ...
International Journal of Antimicrobial Agents 59 (1), 106456, 2022
162022
In-depth analysis of the role of the acinetobactin cluster in the virulence of Acinetobacter baumannii
K Conde-Pérez, JC Vázquez-Ucha, L Álvarez-Fraga, L Ageitos, ...
Frontiers in Microbiology 12, 752070, 2021
152021
Global Transcriptomic Analysis During Murine Pneumonia Infection Reveals New Virulence Factors in Acinetobacter baumannii
M Martínez-Guitián, JC Vázquez-Ucha, L Álvarez-Fraga, K Conde-Pérez, ...
The Journal of Infectious Diseases 223 (8), 1356-1366, 2021
152021
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