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Raul Araya-Secchi
Raul Araya-Secchi
Facultad de Ingeniería, Arquitectura y Diseño. Universidad San Sebastian
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Año
Beyond cell–cell adhesion: sensational cadherins for hearing and balance
A Jaiganesh, Y Narui, R Araya-Secchi, M Sotomayor
Cold Spring Harbor perspectives in biology 10 (9), a029280, 2018
562018
An elastic element in the protocadherin-15 tip link of the inner ear
R Araya-Secchi, BL Neel, M Sotomayor
Nature communications 7 (1), 13458, 2016
552016
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function
O Jara, R Acuña, IE García, J Maripillán, V Figueroa, JC Sáez, ...
Molecular biology of the cell 23 (17), 3299-3311, 2012
532012
Characterization of a novel water pocket inside the human Cx26 hemichannel structure
R Araya-Secchi, T Perez-Acle, S Kang, T Huynh, A Bernardin, Y Escalona, ...
Biophysical journal 107 (3), 599-612, 2014
432014
Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception
D Choudhary, Y Narui, BL Neel, LN Wimalasena, CF Klanseck, ...
Proceedings of the National Academy of Sciences 117 (40), 24837-24848, 2020
372020
Computational modeling study of functional microdomains in cannabinoid receptor type 1
A Gonzalez, LS Duran, R Araya-Secchi, JA Garate, CD Pessoa-Mahana, ...
Bioorganic & medicinal chemistry 16 (8), 4378-4389, 2008
332008
Multidomain convergence of Argonaute during RISC assembly correlates with the formation of internal water clusters
MS Park, R Araya-Secchi, JA Brackbill, HD Phan, AC Kehling, ...
Molecular cell 75 (4), 725-740. e6, 2019
312019
A mechanically weak extracellular membrane-adjacent domain induces dimerization of protocadherin-15
P De-la-Torre, D Choudhary, R Araya-Secchi, Y Narui, M Sotomayor
Biophysical Journal 115 (12), 2368-2385, 2018
302018
Dual Inhibitory Pathways of Metallofullerenol Gd@C82(OH)22 on Matrix Metalloproteinase-2: Molecular insight into drug-like nanomedicine
S Kang, R Araya-Secchi, D Wang, B Wang, T Huynh, R Zhou
Scientific Reports 4 (1), 4775, 2014
292014
Order and disorder—An integrative structure of the full-length human growth hormone receptor
N Kassem, R Araya-Secchi, K Bugge, A Barclay, H Steinocher, ...
Science Advances 7 (27), eabh3805, 2021
232021
Functional characterization of the ATPase-like activity displayed by a catalytic amyloid
C Castillo-Caceres, E Duran-Meza, E Nova, R Araya-Secchi, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129729, 2021
212021
Molecular dynamics study of the archaeal aquaporin AqpM
R Araya-Secchi, JA Garate, DS Holmes, T Perez-Acle
BMC genomics 12, 1-13, 2011
182011
1-benzoyl-2-(2-nitrophenyl)-1H-benzimidazole derivatives: A novel approach to the development of new HIV-1 reverse transcriptase inhibitors
D Vásquez, CF Lagos, J Mella-Raipán, L González, R Ebensperger, ...
Journal of the Chilean Chemical Society 52 (4), 1281-1287, 2007
152007
Exploring the membrane potential of simple dual-membrane systems as models for gap-junction channels
Y Escalona, JA Garate, R Araya-Secchi, T Huynh, R Zhou, T Perez-Acle
Biophysical Journal 110 (12), 2678-2688, 2016
142016
An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum
M Colombres, JA Garate, CF Lagos, R Araya-Secchi, P Norambuena, ...
Journal of computer-aided molecular design 22, 19-28, 2008
132008
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
R Hendus-Altenburger, J Vogensen, ES Pedersen, A Luchini, ...
Communications Biology 3 (1), 731, 2020
102020
Protein Function in Extremely Acidic Conditions: Molecular Simulations of a Predicted Aquaporin and a Potassium Channel in Acidithiobacillus Ferrooxidans
F Duarte, R Araya-Secchi, W González, T Perez-Acle, D González-Nilo, ...
Advanced Materials Research 71, 211-214, 2009
92009
The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4, 5-bisphosphate
R Araya-Secchi, K Bugge, P Seiffert, A Petry, GW Haxholm, ...
Elife 12, e84645, 2023
72023
Collective mechanical responses of cadherin-based adhesive junctions as predicted by simulations
BL Neel, CR Nisler, S Walujkar, R Araya-Secchi, M Sotomayor
Biophysical Journal 121 (6), 991-1012, 2022
62022
Elastic versus brittle mechanical responses predicted for dimeric cadherin complexes
BL Neel, CR Nisler, S Walujkar, R Araya-Secchi, M Sotomayor
Biophysical Journal 121 (6), 1013-1028, 2022
42022
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Artículos 1–20