The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing R Diaz-Gonzalez, FM Kuhlmann, C Galan-Rodriguez, LM da Silva, ... PLoS neglected tropical diseases 5 (8), e1297, 2011 | 92 | 2011 |
Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei A Barquilla, M Saldivia, R Diaz, JM Bart, I Vidal, E Calvo, MN Hall, ... Proceedings of the National Academy of Sciences 109 (36), 14399-14404, 2012 | 84 | 2012 |
The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria‐mediated apoptosis and DNA damage in p53 mutant leukemic T cells MJ Ruiz‐Magaña, JM Rodríguez‐Vargas, JC Morales, MA Saldivia, ... International journal of cancer 130 (5), 1195-1207, 2012 | 61 | 2012 |
The AMPKα1 pathway positively regulates the developmental transition from proliferation to quiescence in Trypanosoma brucei M Saldivia, G Ceballos-Pérez, JM Bart, M Navarro Cell reports 17 (3), 660-670, 2016 | 58 | 2016 |
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors M Saldivia, E Fang, X Ma, E Myburgh, JBT Carnielli, C Bower-Lepts, ... Nature microbiology 5 (10), 1207-1216, 2020 | 48 | 2020 |
Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness JD Seixas, SA Luengo-Arratta, R Diaz, M Saldivia, DI Rojas-Barros, ... Journal of medicinal chemistry 57 (11), 4834-4848, 2014 | 39 | 2014 |
Target of rapamycin (TOR) kinase in Trypanosoma brucei: an extended family M Saldivia, A Barquilla, JM Bart, R Diaz-González, MN Hall, M Navarro Biochemical Society transactions 41 (4), 934-938, 2013 | 31 | 2013 |
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections SPS Rao, MK Gould, J Noeske, M Saldivia, RS Jumani, PS Ng, O René, ... Science 380 (6652), 1349-1356, 2023 | 10 | 2023 |
A CLK1-KKT2 signaling pathway regulating kinetochore assembly in Trypanosoma brucei M Saldivia, AJM Wollman, JBT Carnielli, NG Jones, MC Leake, ... MBio 12 (3), 10.1128/mbio. 00687-21, 2021 | 8 | 2021 |
CLK1/CLK2-driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics V Geoghegan, JBT Carnielli, NG Jones, M Saldivia, S Antoniou, ... Communications biology 5 (1), 1305, 2022 | 2 | 2022 |
Concentración espermática mínima requerida para inseminación intrauterina mediante capacitación por migración ascendente R Lozano-Hernández, M Saldivia, A Villavicencio Revista de Obstetricia y Ginecología de Venezuela 74 (3), 177-183, 2014 | 2 | 2014 |
A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas’ disease M Saldivia, APCA Lima, JC Mottram Trends in Parasitology, 2024 | | 2024 |
Hollow fibre infection model for investigating the long-term culture of trypanosome parasites and their response to therapy R Sterritt, S Lakshminarayana, M Saldivia, D Patra, S Rao, C Osborne BRITISH JOURNAL OF PHARMACOLOGY 177 (11), 2613-2614, 2020 | | 2020 |