Holger Heyn
Holger Heyn
CNAG-CRG
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Global epigenomic reconfiguration during mammalian brain development
R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ...
Science 341 (6146), 2013
14622013
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
J Sandoval, H Heyn, S Moran, J Serra-Musach, MA Pujana, M Bibikova, ...
Epigenetics 6 (6), 692-702, 2011
9622011
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
9562016
Comparative analysis of single-cell RNA sequencing methods
C Ziegenhain, B Vieth, S Parekh, B Reinius, A Guillaumet-Adkins, ...
Molecular cell 65 (4), 631-643. e4, 2017
7682017
DNA methylation profiling in the clinic: applications and challenges
H Heyn, M Esteller
Nature Reviews Genetics 13 (10), 679-692, 2012
7102012
Distinct DNA methylomes of newborns and centenarians
H Heyn, N Li, HJ Ferreira, S Moran, DG Pisano, A Gomez, J Diez, ...
Proceedings of the National Academy of Sciences 109 (26), 10522-10527, 2012
6942012
Machine learning identifies stemness features associated with oncogenic dedifferentiation
TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ...
Cell 173 (2), 338-354. e15, 2018
4362018
DNA methylation contributes to natural human variation
H Heyn, S Moran, I Hernando-Herraez, S Sayols, A Gomez, J Sandoval, ...
Genome research 23 (9), 1363-1372, 2013
3362013
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ...
The Lancet Oncology 17 (10), 1386-1395, 2016
2532016
A prognostic DNA methylation signature for stage I non-small-cell lung cancer
J Sandoval, J Méndez González, E Nadal, G Chen, FJ Carmona, S Sayols, ...
2342013
Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response
I Köllner, B Sodeik, S Schreek, H Heyn, N von Neuhoff, ...
Blood 108 (2), 493-500, 2006
1932006
DNA methylation map of human atherosclerosis
S Zaina, H Heyn, FJ Carmona, N Varol, S Sayols, E Condom, ...
Circulation: Cardiovascular Genetics 7 (5), 692-700, 2014
1842014
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
H Heyn, FJ Carmona, A Gomez, HJ Ferreira, JT Bell, S Sayols, K Ward, ...
Carcinogenesis 34 (1), 102-108, 2013
1592013
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
H Heyn, E Vidal, HJ Ferreira, M Vizoso, S Sayols, A Gomez, S Moran, ...
Genome biology 17 (1), 1-16, 2016
1482016
MicroRNA miR‐335 is crucial for the BRCA1 regulatory cascade in breast cancer development
H Heyn, M Engelmann, S Schreek, P Ahrens, U Lehmann, H Kreipe, ...
International journal of cancer 129 (12), 2797-2806, 2011
1312011
Dynamics of DNA methylation in recent human and great ape evolution
I Hernando-Herraez, J Prado-Martinez, P Garg, M Fernandez-Callejo, ...
PLoS genetics 9 (9), e1003763, 2013
1272013
An adenine code for DNA: a second life for N6-methyladenine
H Heyn, M Esteller
Cell 161 (4), 710-713, 2015
1202015
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns
JV Sanchez-Mut, H Heyn, E Vidal, S Moran, S Sayols, R Delgado-Morales, ...
Translational psychiatry 6 (1), e718-e718, 2016
1132016
RANKL/RANK control Brca1 mutation-driven mammary tumors
V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ...
Cell research 26 (7), 761-774, 2016
1062016
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects
E Mereu, A Lafzi, C Moutinho, C Ziegenhain, DJ McCarthy, ...
Nature Biotechnology 38 (6), 747-755, 2020
1032020
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Artículos 1–20