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Sirkku Jäntti
Sirkku Jäntti
Sr. Scientist
Dirección de correo verificada de helsinki.fi - Página principal
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Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
SI Sayin, A Wahlström, J Felin, S Jäntti, HU Marschall, K Bamberg, ...
Cell metabolism 17 (2), 225-235, 2013
20932013
Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease
P Sen, S Qadri, PK Luukkonen, O Ragnarsdottir, A McGlinchey, S Jäntti, ...
Journal of hepatology 76 (2), 283-293, 2022
1212022
Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease
T Hyötyläinen, L Jerby, EM Petäjä, I Mattila, S Jäntti, P Auvinen, ...
Nature communications 7 (1), 8994, 2016
1142016
Human serum metabolites associate with severity and patient outcomes in traumatic brain injury
M Orešič, JP Posti, MH Kamstrup-Nielsen, RSK Takala, HF Lingsma, ...
EBioMedicine 12, 118-126, 2016
882016
Quantitative profiling of bile acids in blood, adipose tissue, intestine, and gall bladder samples using ultra high performance liquid chromatography-tandem mass spectrometry
SE Jäntti, M Kivilompolo, L Öhrnberg, KH Pietiläinen, H Nygren, M Orešič, ...
Analytical and bioanalytical chemistry 406, 7799-7815, 2014
702014
Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases
JM Little, M Kurkela, J Sonka, S Jäntti, R Ketola, S Bratton, M Finel, ...
Journal of lipid research 45 (9), 1694-1703, 2004
672004
Determination of steroids and their intact glucuronide conjugates in mouse brain by capillary liquid chromatography-tandem mass spectrometry
SE Jantti, A Tammimaki, H Raattamaa, P Piepponen, R Kostiainen, ...
Analytical chemistry 82 (8), 3168-3175, 2010
492010
Stereoselective aza Diels− Alder reaction on solid phase: A facile synthesis of hexahydrocinnoline derivatives
A Kiriazis, T Rüffer, S Jäntti, H Lang, J Yli-Kauhaluoma
Journal of Combinatorial Chemistry 9 (2), 263-266, 2007
472007
The influence of sample collection methodology and sample preprocessing on the blood metabolic profile
B Jørgenrud, S Jäntti, I Mattila, P Pöhö, KS Rønningen, H Yki-Järvinen, ...
Bioanalysis 7 (8), 991-1006, 2015
422015
Enzyme-assisted synthesis and structure characterization of glucuronic acid conjugates of losartan, candesartan, and zolarsartan
A Alonen, J Jansson, S Kallonen, A Kiriazis, O Aitio, M Finel, R Kostiainen
Bioorganic chemistry 36 (3), 148-155, 2008
392008
Capillary liquid chromatography–microchip atmospheric pressure chemical ionization–mass spectrometry
P Östman, S Jäntti, K Grigoras, V Saarela, RA Ketola, S Franssila, ...
Lab on a Chip 6 (7), 948-953, 2006
392006
Enzyme-assisted synthesis and characterization of glucuronide conjugates of neuroactive steroids
SE Jäntti, A Kiriazis, RR Reinilä, RK Kostiainen, RA Ketola
Steroids 72 (3), 287-296, 2007
382007
Targeted clinical metabolite profiling platform for the stratification of diabetic patients
L Ahonen, S Jäntti, T Suvitaival, S Theilade, C Risz, R Kostiainen, ...
Metabolites 9 (9), 184, 2019
252019
Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography–electrospray ionization-tandem mass spectrometry
SE Jäntti, M Hartonen, M Hilvo, H Nygren, T Hyötyläinen, RA Ketola, ...
Analytica chimica acta 802, 56-66, 2013
182013
Discovery of neurosteroid glucuronides in mouse brain
SE Kallonen, A Tammimäki, P Piepponen, H Raattamaa, RA Ketola, ...
Analytica chimica acta 651 (1), 69-74, 2009
162009
Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species
AØ Petersen, H Julienne, T Hyötyläinen, P Sen, Y Fan, HK Pedersen, ...
Scientific Reports 11 (1), 13252, 2021
92021
The Sonogashira Coupling of Polymer‐Supported Propargylamine with Aryl Iodides
T Leikoski, S Kallonen, J Yli‐Kauhaluoma
Helvetica chimica acta 93 (1), 39-47, 2010
72010
Depuy-Synthes Award for Resident Research on Brain and Craniofacial Injury 155; Blood Metabolic Patterns Correlate With the Severity of Traumatic Brain Injury
J Posti, T Hyötyläinen, S Jäntti, H Ala-Seppälä, J Coles, A Katila, ...
Neurosurgery 61, 211, 2014
12014
Exposure to environmental contaminants is associated with sex-specific disturbances of hepatic lipid metabolism in non-alcoholic fatty liver disease
M Oresic, P Sen, S Quadri, P Luukkonen, O Ragnarsdottir, S Jäntti, A Juuti, ...
Journal of Hepatology 75 (Suppl. 2), S605-S606, 2021
2021
Targeted Clinical Metabolomics Platform for the Stratification of Diabetic Patients
L Ahonen, S Jäntti, T Suvitaival, S Theilade, C Risz, R Kostiainen, ...
bioRxiv, 664052, 2019
2019
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Artículos 1–20