|Primary cilia are not calcium-responsive mechanosensors|
M Delling, AA Indzhykulian, X Liu, Y Li, T Xie, DP Corey, DE Clapham
Nature 531 (7596), 656-660, 2016
|Alterations of the CIB2 calcium-and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48|
S Riazuddin, IA Belyantseva, APJ Giese, K Lee, AA Indzhykulian, ...
Nature genetics 44 (11), 1265, 2012
|Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c|
B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ...
Nature biotechnology 35 (3), 264, 2017
|Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells|
AA Indzhykulian, R Stepanyan, A Nelina, KJ Spinelli, ZM Ahmed, ...
PLoS biology 11 (6), e1001583, 2013
|Rescue of hearing by gene delivery to inner-ear hair cells using exosome-associated AAV|
B György, C Sage, AA Indzhykulian, DI Scheffer, AR Brisson, S Tan, X Wu, ...
Molecular Therapy 25 (2), 379-391, 2017
|TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells|
RS Stepanyan, AA Indzhykulian, AC Vélez-Ortega, ET Boger, PS Steyger, ...
Journal of the Association for Research in Otolaryngology 12 (6), 729-740, 2011
|Tryptophan‐rich basic protein (WRB) mediates insertion of the tail‐anchored protein otoferlin and is required for hair cell exocytosis and hearing|
C Vogl, I Panou, G Yamanbaeva, C Wichmann, SJ Mangosing, F Vilardi, ...
The EMBO journal 35 (23), 2536-2552, 2016
|The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing|
Q Fang, AA Indzhykulian, M Mustapha, GP Riordan, DF Dolan, ...
Elife 4, e08627, 2015
|Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells|
AC Vélez-Ortega, MJ Freeman, AA Indzhykulian, JM Grossheim, ...
Elife 6, e24661, 2017
|XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia|
DI Scheffer, DS Zhang, J Shen, A Indzhykulian, KD Karavitaki, YJ Xu, ...
Cell reports 10 (11), 1811-1818, 2015
|Gene transfer with AAV9-PHP. B rescues hearing in a mouse model of usher syndrome 3A and transduces hair cells in a non-human primate|
B György, EJ Meijer, MV Ivanchenko, K Tenneson, F Emond, KS Hanlon, ...
Molecular Therapy-Methods & Clinical Development 13, 1-13, 2019
|Hair-cell mechanotransduction persists in TRP channel knockout mice|
X Wu, AA Indzhykulian, PD Niksch, RM Webber, M Garcia-Gonzalez, ...
PLoS One 11 (5), e0155577, 2016
|Two-step regeneration of mechanotransduction and molecular composition of the tip links in mammalian cochlear inner hair cells|
A Indzhykulian, R Stepanyan, G Frolenkov
Assoc. Res. Otolaryngol. Abstr 35, 204, 2012
|In the Right Place at the Right Time: Is TMC1/2 the Transduction Channel for Hearing?|
AA Indzhykulian, DP Corey
Cell reports 12 (10), 1531-1532, 2015
|Renewed proliferation in adult mouse cochlea and regeneration of hair cells|
Y Shu, W Li, M Huang, YZ Quan, D Scheffer, C Tian, Y Tao, X Liu, ...
Nature Communications 10 (1), 1-15, 2019
|PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing|
X Wu, MV Ivanchenko, H Al Jandal, M Cicconet, AA Indzhykulian, ...
Nature communications 10 (1), 1-15, 2019
|A Single Neonatal Injection of PHP. B-AAV9-Clrn1 Rescues Hearing in a Model of Usher Syndrome Type IIIa|
B Gyorgy, EJ Meijer, A Indzhykulian, A Volak, SG Leroy, CA Maguire, ...
MOLECULAR THERAPY 26 (5), 170-171, 2018
|Gene Therapy Restores Auditory and Vestibular Function in a Mouse Model for Usher Syndrome Type 1C|
C Askew, B Pan, A Galvin, SS Heman-Ackah, Y Asai, AA Indzhykulian, ...
MOLECULAR THERAPY 25 (5), 352-352, 2017
|Primary cilia of inner ear hair cells do not respond to mechanical stimuli|
AA Indzhykulian, M Delling, X Liu, Y Li, T Xie, DP Corey, DE Clapham
The FASEB Journal 30 (1_supplement), 12.2-12.2, 2016
|In search of the cochlear amplifier: New mechanical and molecular tools to probe transduction channel function|
KD Karavitaki, AA Indzhykulian, DS Zhang, DP Corey
AIP Conference Proceedings 1703 (1), 030004, 2015