Marcelo A. Lima
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Heparan sulfate and heparin interactions with proteins
MCZ Meneghetti, AJ Hughes, TR Rudd, HB Nader, AK Powell, EA Yates, ...
Journal of the Royal Society Interface 12 (110), 20150589, 2015
Anti-inflammatory properties of a heparin-like glycosaminoglycan with reduced anti-coagulant activity isolated from a marine shrimp
AS Brito, DS Arimatéia, LR Souza, MA Lima, VO Santos, VP Medeiros, ...
Bioorganic & medicinal chemistry 16 (21), 9588-9595, 2008
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding.
CJ Mycroft-West, D Su, S Elli, Y Li, SE Guimond, GJ Miller, JE Turnbull, ...
BioRxiv, 2020
A new approach for heparin standardization: Combination of scanning UV spectroscopy, nuclear magnetic resonance and principal component analysis
MA Lima, TR Rudd, EHC de Farias, LF Ebner, TF Gesteira, LM de Souza, ...
PLoS One 6 (1), e15970, 2011
Heparin prevents Zika virus induced-cytopathic effects in human neural progenitor cells
S Ghezzi, L Cooper, A Rubio, I Pagani, MR Capobianchi, G Ippolito, ...
Antiviral research 140, 13-17, 2017
A heparin mimetic isolated from a marine shrimp suppresses neovascularization
JL Dreyfuss, CV Regatieri, MA Lima, EJ PAREDES‐GAMERO, AS Brito, ...
Journal of Thrombosis and Haemostasis 8 (8), 1828-1837, 2010
A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential
AS Brito, RS Cavalcante, LCGF Palhares, AJ Hughes, GPV Andrade, ...
Carbohydrate polymers 99, 372-378, 2014
Atomic details of the interactions of glycosaminoglycans with amyloid-β fibrils
KL Stewart, E Hughes, EA Yates, GR Akien, TY Huang, MA Lima, ...
Journal of the American Chemical Society 138 (27), 8328-8331, 2016
New applications of heparin and other glycosaminoglycans
M Lima, T Rudd, E Yates
Molecules 22 (5), 749, 2017
A heparin-like glycosaminoglycan from shrimp containing high levels of 3-O-sulfated D-glucosamine groups in an unusual trisaccharide sequence
SF Chavante, AS Brito, M Lima, E Yates, H Nader, M Guerrini, G Torri, ...
Carbohydrate research 390, 59-66, 2014
A heparin-like compound isolated from a marine crab rich in glucuronic acid 2-O-sulfate presents low anticoagulant activity
GPV Andrade, MA Lima, AA de Souza Junior, J Fareed, DA Hoppensteadt, ...
Carbohydrate polymers 94 (1), 647-654, 2013
High-sensitivity visualisation of contaminants in heparin samples by spectral filtering of 1H NMR spectra
TR Rudd, D Gaudesi, MA Lima, MA Skidmore, B Mulloy, G Torri, ...
Analyst 136 (7), 1390-1398, 2011
Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity
MA Lima, AJ Hughes, N Veraldi, TR Rudd, R Hussain, AS Brito, ...
MedChemComm 4 (5), 870-873, 2013
Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases
CM Vicente, MA Lima, EA Yates, HB Nader, L Toma
Molecular Cancer Research 13 (3), 510-523, 2015
Lepstospira interrogans shotgun phage display identified LigB as a heparin-binding protein
ATC Ching, RD Fávaro, SS Lima, AAM Chaves, MA de Lima, HB Nader, ...
Biochemical and biophysical research communications 427 (4), 774-779, 2012
A robust method to quantify low molecular weight contaminants in heparin: detection of tris (2-n-butoxyethyl) phosphate
GL Sassaki, DS Riter, AP Santana Filho, M Guerrini, MA Lima, ...
Analyst 136 (11), 2330-2338, 2011
Coupling of vinculin to F-actin demands Syndecan-4 proteoglycan
RP Cavalheiro, MA Lima, TR Jarrouge-Bouças, GM Viana, CC Lopes, ...
Matrix Biology 63, 23-37, 2017
Active site mapping of Loxosceles phospholipases D: Biochemical and biological features
L Vuitika, D Chaves-Moreira, I Caruso, MA Lima, FH Matsubara, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016
SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells
CM Vicente, MA Lima, HB Nader, L Toma
Journal of Experimental & Clinical Cancer Research 34 (1), 1-16, 2015
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin.
C Mycroft-West, D Su, I Pagani, T Rudd, S Elli, S Guimond, G Miller, ...
bioRxiv, 2020
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