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James J Douglas
James J Douglas
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
A scalable and operationally simple radical trifluoromethylation
JW Beatty, JJ Douglas, KP Cole, CRJ Stephenson
Nature communications 6, 2015
3552015
Visible light photocatalysis: applications and new disconnections in the synthesis of pharmaceutical agents
JJ Douglas, MJ Sevrin, CRJ Stephenson
Organic Process Research & Development 20 (7), 1134-1147, 2016
3442016
Photoinduced Remote Functionalizations via Iminyl Radical‐Promoted C‐C and C‐H Bond Cleavage Cascades.
EM Dauncey, SP Marcillo, JJ Douglas, NS Sheikh, D Leonori
Angewandte Chemie International Edition, 2017
3432017
NHCs in asymmetric organocatalysis: recent advances in azolium enolate generation and reactivity
J Douglas, G Churchill, AD Smith
Synthesis 44 (15), 2295-2309, 2012
2882012
Hydroxylamine Derivatives as Nitrogen‐Radical Precursors in Visible‐Light Photochemistry
J Davies, SP Morcillo, JJ Douglas, D Leonori
Chemistry–A European Journal, 2018
2332018
Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale
JW Beatty, JJ Douglas, R Miller, RC McAtee, KP Cole, CRJ Stephenson
Chem 1 (3), 456-472, 2016
2262016
Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals
SP Morcillo, EM Dauncey, JH Kim, JJ Douglas, NS Sheikh, D Leonori
Angewandte Chemie International Edition, 2018
2112018
Photocatalysis in the Life Science Industry
L Candish, KD Collins, GC Cook, JJ Douglas, A Gómez-Suárez, A Jolit, ...
Chemical Reviews, 2021
2072021
Practical and regioselective amination of arenes using alkyl amines
A Ruffoni, F Juliá, TD Svejstrup, AJ McMillan, JJ Douglas, D Leonori
Nature chemistry, 1, 2019
1962019
A Visible‐Light‐Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluoro‐Substituted Spirocyclic ORL‐1 Antagonist
JJ Douglas, H Albright, MJ Sevrin, KP Cole, CRJ Stephenson
Angewandte Chemie International Edition 54 (49), 14898-14902, 2015
1632015
A photochemical dehydrogenative strategy for aniline synthesis
SU Dighe, F Juliá, A Luridiana, JJ Douglas, D Leonori
Nature 584 (7819), 75-81, 2020
1292020
Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study
LC Morrill, J Douglas, T Lebl, AMZ Slawin, DJ Fox, AD Smith
Chemical Science 4 (11), 4146-4155, 2013
1232013
Ligand functionalization as a deactivation pathway in a fac-Ir (ppy) 3-mediated radical addition
JJ Devery III, JJ Douglas, JD Nguyen, KP Cole, RA Flowers II, ...
Chemical Science 6 (1), 537-541, 2015
1072015
Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines
SR Smith, J Douglas, H Prevet, P Shapland, AMZ Slawin, AD Smith
The Journal of organic chemistry 79 (4), 1626-1639, 2014
932014
Photoredox Catalysis in a Complex Pharmaceutical Setting: Toward the Preparation of JAK2 Inhibitor LY2784544
JJ Douglas, KP Cole, CRJ Stephenson
The Journal of organic chemistry 79 (23), 11631-11643, 2014
892014
Copper-catalysed amination of alkyl iodides enabled by halogen-atom transfer
B Górski, AL Barthelemy, JJ Douglas, F Juliá, D Leonori
Nature Catalysis, 1-8, 2021
882021
A Dual Photoredox-Nickel Strategy for Remote Functionalization via Iminyl Radicals: Radical Ring-Opening–Arylation,–Vinylation and–Alkylation Cascades
E Dauncey, SU Dighe, JJ Douglas, D Leonori
Chemical Science, 2019
742019
NHC-Promoted asymmetric β-lactone formation from arylalkylketenes and electron-deficient benzaldehydes or pyridinecarboxaldehydes
J Douglas, JE Taylor, G Churchill, AMZ Slawin, AD Smith
The Journal of organic chemistry 78 (8), 3925-3938, 2013
742013
Stereospecific asymmetric N-heterocyclic carbene (NHC)-catalyzed redox synthesis of trifluoromethyl dihydropyranones and mechanistic insights
AT Davies, JE Taylor, J Douglas, CJ Collett, LC Morrill, C Fallan, ...
The Journal of organic chemistry 78 (18), 9243-9257, 2013
732013
Enabling Novel Photoredox Reactivity via Photocatalyst Selection
JJ Douglas, JD Nguyen, KP Cole, CRJ Stephenson
Aldrichimica Acta 47 (1), 15-25, 2014
572014
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Articles 1–20