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Robert A. Amezquita, PhD
Robert A. Amezquita, PhD
Sr Computational Immunologist
Dirección de correo verificada de pfizer.com
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Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
12242015
Orchestrating single-cell analysis with Bioconductor
RA Amezquita, ATL Lun, E Becht, VJ Carey, LN Carpp, L Geistlinger, ...
Nature methods 17 (2), 137-145, 2020
5852020
IL-7-induced glycerol transport and TAG synthesis promotes memory CD8+ T cell longevity
G Cui, MM Staron, SM Gray, PC Ho, RA Amezquita, J Wu, SM Kaech
Cell 161 (4), 750-761, 2015
3282015
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection
CX Dominguez, RA Amezquita, T Guan, HD Marshall, NS Joshi, ...
Journal of Experimental Medicine 212 (12), 2041-2056, 2015
2512015
Polycomb repressive complex 2-mediated chromatin repression guides effector CD8+ T cell terminal differentiation and loss of multipotency
SM Gray, RA Amezquita, T Guan, SH Kleinstein, SM Kaech
Immunity 46 (4), 596-608, 2017
2142017
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
BJ Laidlaw, W Cui, RA Amezquita, SM Gray, T Guan, Y Lu, Y Kobayashi, ...
Nature immunology 16 (8), 871-879, 2015
2042015
Immunogenic chemotherapy enhances recruitment of CAR-T cells to lung tumors and improves antitumor efficacy when combined with checkpoint blockade
S Srivastava, SN Furlan, CA Jaeger-Ruckstuhl, M Sarvothama, C Berger, ...
Cancer cell 39 (2), 193-208. e10, 2021
1892021
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response
BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ...
Science immunology 2 (16), eaan4767, 2017
1702017
Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity
CJ Perry, AR Muñoz-Rojas, KM Meeth, LN Kellman, RA Amezquita, ...
Journal of Experimental Medicine 215 (3), 877-893, 2018
1402018
ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates
T Guan, CX Dominguez, RA Amezquita, BJ Laidlaw, J Cheng, ...
Journal of Experimental Medicine 215 (4), 1153-1168, 2018
1192018
IL-17 promotes neutrophil-mediated immunity by activating microvascular pericytes and not endothelium
R Liu, HM Lauridsen, RA Amezquita, RW Pierce, D Jane-Wit, C Fang, ...
The Journal of Immunology 197 (6), 2400-2408, 2016
1112016
Autoreactive T cells from patients with myasthenia gravis are characterized by elevated IL-17, IFN-γ, and GM-CSF and diminished IL-10 production
Y Cao, RA Amezquita, SH Kleinstein, P Stathopoulos, RJ Nowak, ...
The Journal of Immunology 196 (5), 2075-2084, 2016
832016
The chronicles of T-cell exhaustion
RA Amezquita, SM Kaech
Nature 543 (7644), 190-191, 2017
332017
NK cell responses redefine immunological memory
NM Adams, TE O’Sullivan, CD Geary, JM Karo, RA Amezquita, NS Joshi, ...
The Journal of Immunology 197 (8), 2963-2970, 2016
332016
Defining cellular population dynamics at single-cell resolution during prostate cancer progression
AA Germanos, S Arora, Y Zheng, ET Goddard, IM Coleman, AT Ku, ...
Elife 11, e79076, 2022
82022
Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma
C Church, T Pulliam, N Longino, SY Park, KS Smythe, V Makarov, N Riaz, ...
Journal for immunotherapy of cancer 10 (9), 2022
82022
Publisher Correction: Orchestrating single-cell analysis with Bioconductor
RA Amezquita, ATL Lun, E Becht, VJ Carey, LN Carpp, L Geistlinger, ...
Nature methods 17 (2), 242, 2020
72020
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
HN Thirimanne, F Wu, DH Janssens, J Swanger, A Diab, HM Feldman, ...
Elife 11, e74338, 2022
62022
Th2-biased transcriptional profile predicts HIV envelope-specific polyfunctional CD4+ T cells that correlated with reduced risk of infection in RV144 Trial
KW Cohen, Y Tian, C Thayer, A Seese, R Amezquita, MJ McElrath, ...
The Journal of Immunology 209 (3), 526-534, 2022
32022
marge: An API for Analysis of Motifs Using HOMER in R
RA Amezquita
bioRxiv, 249268, 2018
32018
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20