1, 4-Dihydropyridines as alkyl radical precursors: introducing the aldehyde feedstock to nickel/photoredox dual catalysis A Gutiérrez-Bonet, JC Tellis, JK Matsui, BA Vara, GA Molander ACS catalysis 6 (12), 8004-8008, 2016 | 238 | 2016 |
Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis BA Vara, X Li, S Berritt, CR Walters, EJ Petersson, GA Molander Chemical Science 9 (2), 336-344, 2018 | 146 | 2018 |
Enantioselective small molecule synthesis by carbon dioxide fixation using a dual Brønsted acid/base organocatalyst BA Vara, TJ Struble, W Wang, MC Dobish, JN Johnston Journal of the American Chemical Society 137 (23), 7302-7305, 2015 | 125 | 2015 |
O-Benzyl Xanthate Esters under Ni/Photoredox Dual Catalysis: Selective Radical Generation and Csp3–Csp2 Cross-Coupling BA Vara, NR Patel, GA Molander ACS catalysis 7 (6), 3955-3959, 2017 | 83 | 2017 |
C (sp 3)–C (sp 2) cross-coupling of alkylsilicates with borylated aryl bromides–an iterative platform to alkylated aryl-and heteroaryl boronates BA Vara, M Jouffroy, GA Molander Chemical Science 8 (1), 530-535, 2017 | 48 | 2017 |
Organocatalytic, diastereo-and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for … BA Vara, A Mayasundari, JC Tellis, MW Danneman, V Arredondo, ... The Journal of Organic Chemistry 79 (15), 6913-6938, 2014 | 47 | 2014 |
Enantioselective synthesis of β-fluoro amines via β-amino α-fluoro nitroalkanes and a traceless activating group strategy BA Vara, JN Johnston Journal of the American Chemical Society 138 (42), 13794-13797, 2016 | 43 | 2016 |
Discovery of diaminopyrimidine carboxamide HPK1 inhibitors as preclinical immunotherapy tool compounds BA Vara, SM Levi, A Achab, DA Candito, X Fradera, CA Lesburg, ... ACS Medicinal Chemistry Letters 12 (4), 653-661, 2021 | 26 | 2021 |
Synthesis of 1, 3-diols by O-nucleophile additions to activated alkenes D Gamba-Sánchez, J Prunet Synthesis 50 (20), 3997-4007, 2018 | 19 | 2018 |
Reductive sp3–sp2 Coupling Reactions Enable Late-Stage Modification of Pharmaceuticals KM Mennie, BA Vara, SM Levi Organic letters 22 (2), 556-559, 2020 | 17 | 2020 |
Adaptation of a small-molecule hydrogen-bond donor catalyst to an enantioselective hetero-Diels–Alder reaction hypothesized for brevianamide biosynthesis DJ Sprague, BM Nugent, RA Yoder, BA Vara, JN Johnston Organic letters 17 (4), 880-883, 2015 | 16 | 2015 |
ACS Catal., 2016, 6, 8004–8008;(b) L. Buzzetti, A. Prieto, SR Roy and P. Melchiorre Á Gutiérrez-Bonet, JC Tellis, JK Matsui, BA Vara, GA Molander Angew. Chem., Int. Ed 56, 15039-15043, 2017 | 11 | 2017 |
Catal. 2016, 6, 8004–8008; d) K. Nakajima, S. Nojima, Y. Nishibayashi JC GutiØrrez-Bonet, JK Tellis, BA Matsui, GA Vara, ACS Molander Angew. Chem. Int. Ed 55, 14106-14110, 2016 | 11 | 2016 |
MDM2 antagonists counteract drug-induced DNA damage AE Vilgelm, P Cobb, K Malikayil, D Flaherty, CA Johnson, D Raman, ... EBioMedicine 24, 43-55, 2017 | 10 | 2017 |
Chlorination of Conjugated Nitroalkenes with PhICl2 and SO2Cl2 for the Synthesis of α-Chloronitroalkenes AA Fadeeva, SL Ioffe, AA Tabolin Synthesis 52 (18), 2679-2688, 2020 | 8 | 2020 |
The n-dig-Cyclization (n= 5, 6) of Alkynes Involving Fixation of CO2 B Wang, S Sun, J Cheng Synlett 29 (14), 1814-1822, 2018 | 6 | 2018 |
Construction of C–C Bond via C–N and C–O Cleavage X Pang, RD He, XZ Shu Synlett 31 (07), 635-640, 2020 | 3 | 2020 |
Diaminopyrimidine carboxamide inhibitors of hpk1 A Achab, DA Candito, A Donofrio, X Fradera, S Kawamura, SM Levi, B Li, ... US Patent App. 18/251,259, 2023 | 1 | 2023 |
Aryl ether compounds as tead modulators J Lim, V Simov, BA Vara, CS Yeung, SE Schneider, EF DiMauro US Patent App. 18/264,468, 2024 | | 2024 |
Activation of hepatocyte growth factor (HGF)/MET signaling as a mechanism of acquired resistance to a novel YAP1/TEAD small molecule inhibitor CJ Moure, B Vara, MM Cheng, C Sondey, E Muise, E Park, ... Molecular Cancer Therapeutics, 2024 | | 2024 |