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Brandon A. Vara, Ph.D.
Brandon A. Vara, Ph.D.
University of Pennsylvania, Merck & Co (MRL)
Verified email at merck.com
Title
Cited by
Cited by
Year
1, 4-Dihydropyridines as alkyl radical precursors: introducing the aldehyde feedstock to nickel/photoredox dual catalysis
A Gutiérrez-Bonet, JC Tellis, JK Matsui, BA Vara, GA Molander
ACS catalysis 6 (12), 8004-8008, 2016
2382016
Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis
BA Vara, X Li, S Berritt, CR Walters, EJ Petersson, GA Molander
Chemical Science 9 (2), 336-344, 2018
1462018
Enantioselective small molecule synthesis by carbon dioxide fixation using a dual Brønsted acid/base organocatalyst
BA Vara, TJ Struble, W Wang, MC Dobish, JN Johnston
Journal of the American Chemical Society 137 (23), 7302-7305, 2015
1252015
O-Benzyl Xanthate Esters under Ni/Photoredox Dual Catalysis: Selective Radical Generation and Csp3–Csp2 Cross-Coupling
BA Vara, NR Patel, GA Molander
ACS catalysis 7 (6), 3955-3959, 2017
832017
C (sp 3)–C (sp 2) cross-coupling of alkylsilicates with borylated aryl bromides–an iterative platform to alkylated aryl-and heteroaryl boronates
BA Vara, M Jouffroy, GA Molander
Chemical Science 8 (1), 530-535, 2017
482017
Organocatalytic, diastereo-and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for …
BA Vara, A Mayasundari, JC Tellis, MW Danneman, V Arredondo, ...
The Journal of Organic Chemistry 79 (15), 6913-6938, 2014
472014
Enantioselective synthesis of β-fluoro amines via β-amino α-fluoro nitroalkanes and a traceless activating group strategy
BA Vara, JN Johnston
Journal of the American Chemical Society 138 (42), 13794-13797, 2016
432016
Discovery of diaminopyrimidine carboxamide HPK1 inhibitors as preclinical immunotherapy tool compounds
BA Vara, SM Levi, A Achab, DA Candito, X Fradera, CA Lesburg, ...
ACS Medicinal Chemistry Letters 12 (4), 653-661, 2021
262021
Synthesis of 1, 3-diols by O-nucleophile additions to activated alkenes
D Gamba-Sánchez, J Prunet
Synthesis 50 (20), 3997-4007, 2018
192018
Reductive sp3–sp2 Coupling Reactions Enable Late-Stage Modification of Pharmaceuticals
KM Mennie, BA Vara, SM Levi
Organic letters 22 (2), 556-559, 2020
172020
Adaptation of a small-molecule hydrogen-bond donor catalyst to an enantioselective hetero-Diels–Alder reaction hypothesized for brevianamide biosynthesis
DJ Sprague, BM Nugent, RA Yoder, BA Vara, JN Johnston
Organic letters 17 (4), 880-883, 2015
162015
ACS Catal., 2016, 6, 8004–8008;(b) L. Buzzetti, A. Prieto, SR Roy and P. Melchiorre
Á Gutiérrez-Bonet, JC Tellis, JK Matsui, BA Vara, GA Molander
Angew. Chem., Int. Ed 56, 15039-15043, 2017
112017
Catal. 2016, 6, 8004–8008; d) K. Nakajima, S. Nojima, Y. Nishibayashi
JC GutiØrrez-Bonet, JK Tellis, BA Matsui, GA Vara, ACS Molander
Angew. Chem. Int. Ed 55, 14106-14110, 2016
112016
MDM2 antagonists counteract drug-induced DNA damage
AE Vilgelm, P Cobb, K Malikayil, D Flaherty, CA Johnson, D Raman, ...
EBioMedicine 24, 43-55, 2017
102017
Chlorination of Conjugated Nitroalkenes with PhICl2 and SO2Cl2 for the Synthesis of α-Chloronitroalkenes
AA Fadeeva, SL Ioffe, AA Tabolin
Synthesis 52 (18), 2679-2688, 2020
82020
The n-dig-Cyclization (n= 5, 6) of Alkynes Involving Fixation of CO2
B Wang, S Sun, J Cheng
Synlett 29 (14), 1814-1822, 2018
62018
Construction of C–C Bond via C–N and C–O Cleavage
X Pang, RD He, XZ Shu
Synlett 31 (07), 635-640, 2020
32020
Diaminopyrimidine carboxamide inhibitors of hpk1
A Achab, DA Candito, A Donofrio, X Fradera, S Kawamura, SM Levi, B Li, ...
US Patent App. 18/251,259, 2023
12023
Aryl ether compounds as tead modulators
J Lim, V Simov, BA Vara, CS Yeung, SE Schneider, EF DiMauro
US Patent App. 18/264,468, 2024
2024
Activation of hepatocyte growth factor (HGF)/MET signaling as a mechanism of acquired resistance to a novel YAP1/TEAD small molecule inhibitor
CJ Moure, B Vara, MM Cheng, C Sondey, E Muise, E Park, ...
Molecular Cancer Therapeutics, 2024
2024
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