Celia Perales
Celia Perales
Celia Perales, PhD Científico Titular del CSIC (Centro Nacional de Biotecnología) Investigadora
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Viral quasispecies evolution
E Domingo, J Sheldon, C Perales
Microbiology and Molecular Biology Reviews 76 (2), 159-216, 2012
Viruses as quasispecies: biological implications
E Domingo, V Martin, C Perales, A Grande-Perez, J Garcia-Arriaza, ...
Quasispecies: concept and implications for virology, 51-82, 2006
Viral quasispecies
E Domingo, C Perales
PLoS genetics 15 (10), e1008271, 2019
HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation
I Ventoso, R Blanco, C Perales, L Carrasco
Proceedings of the National Academy of Sciences 98 (23), 12966-12971, 2001
Virus evolution
E Domingo
Fields virology 5, 391-422, 2007
Viral genome segmentation can result from a trade-off between genetic content and particle stability
S Ojosnegros, J Garcia-Arriaza, C Escarmis, SC Manrubia, C Perales, ...
PLoS genetics 7 (3), e1001344, 2011
Viral quasispecies complexity measures
J Gregori, C Perales, F Rodriguez-Frias, JI Esteban, J Quer, E Domingo
Virology 493, 227-237, 2016
Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants
C Perales, R Mateo, MG Mateu, E Domingo
Journal of molecular biology 369 (4), 985-1000, 2007
High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods
J Quer, J Gregori, F Rodríguez-Frias, M Buti, A Madejon, ...
Journal of clinical microbiology 53 (1), 219-226, 2015
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape
R Agudo, C Ferrer-Orta, A Arias, I de la Higuera, C Perales, ...
PLoS pathogens 6 (8), e1001072, 2010
Mutation rates, mutation frequencies, and proofreading-repair activities in RNA virus genetics
E Domingo, C García-Crespo, R Lobo-Vega, C Perales
Viruses 13 (9), 1882, 2021
Lethal mutagenesis of hepatitis C virus induced by favipiravir
AI De Ávila, I Gallego, ME Soria, J Gregori, J Quer, JI Esteban, CM Rice, ...
PloS one 11 (10), e0164691, 2016
Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus
J Sheldon, NM Beach, E Moreno, I Gallego, D Piñeiro, E Martínez-Salas, ...
Journal of virology 88 (20), 12098-12111, 2014
Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype
C Perales, NM Beach, I Gallego, ME Soria, J Quer, JI Esteban, C Rice, ...
Journal of virology 87 (13), 7593-7607, 2013
Quasispecies as a matter of fact: viruses and beyond
S Ojosnegros, C Perales, A Mas, E Domingo
Virus research 162 (1-2), 203-215, 2011
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections
C Perales, R Agudo, H Tejero, SC Manrubia, E Domingo
PLoS pathogens 5 (11), e1000658, 2009
Quasispecies and virus
E Domingo, C Perales
European Biophysics Journal 47 (4), 443-457, 2018
Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis
AM Ortega-Prieto, J Sheldon, A Grande-Pérez, H Tejero, J Gregori, J Quer, ...
PloS one 8 (8), e71039, 2013
Extracellular vesicles: Vehicles of en bloc viral transmission
N Altan-Bonnet, C Perales, E Domingo
Virus research 265, 143-149, 2019
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
E Pairo-Castineira, K Rawlik, AD Bretherick, T Qi, Y Wu, I Nassiri, ...
Nature 617 (7962), 764-768, 2023
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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