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Bjarte Aarmo Lund
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A focused fragment library targeting the antibiotic resistance enzyme-Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
S Akhter, BA Lund, A Ismael, M Langer, J Isaksson, T Christopeit, ...
European journal of medicinal chemistry 145, 634-648, 2018
352018
Dissemination and characteristics of a novel plasmid-encoded carbapenem-hydrolyzing class D β-lactamase, OXA-436, found in isolates from four patients at six different …
Ø Samuelsen, F Hansen, B Aasnæs, H Hasman, BA Lund, HKS Leiros, ...
Antimicrobial Agents and Chemotherapy 62 (1), 10.1128/aac. 01260-17, 2018
312018
Screening and design of inhibitor scaffolds for the antibiotic resistance oxacillinase-48 (OXA-48) through surface plasmon resonance screening
BA Lund, T Christopeit, Y Guttormsen, A Bayer, HKS Leiros
Journal of Medicinal Chemistry 59 (11), 5542-5554, 2016
302016
Addressing the glycine‐rich loop of protein kinases by a multi‐facetted interaction network: inhibition of PKA and a PKB mimic
BS Lauber, LA Hardegger, AK Asraful, BA Lund, O Dumele, M Harder, ...
Chemistry–A European Journal 22 (1), 211-221, 2016
292016
A high-throughput, restriction-free cloning and screening strategy based on ccd B-gene replacement
BA Lund, HKS Leiros, GEK Bjerga
Microbial Cell Factories 13, 1-7, 2014
282014
The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity
BA Lund, AM Thomassen, BHB Nesheim, TJO Carlsen, J Isaksson, ...
The FEBS Journal 285 (22), 4214-4228, 2018
152018
Cryptic β-lactamase evolution is driven by low β-lactam concentrations
C Fröhlich, JA Gama, K Harms, VHA Hirvonen, BA Lund, ...
Msphere 6 (2), 10.1128/msphere. 00108-21, 2021
142021
Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool
E Åberg, B Lund, A Pflug, OA Gani, U Rothweiler, TM de Oliveira, ...
Biological chemistry 393 (10), 1121-1129, 2012
142012
Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis
BA Lund, AM Thomassen, TJO Carlsen, HKS Leiros
Acta Crystallographica Section F: Structural Biology Communications 73 (10 …, 2017
132017
Structure and mechanism of a cold-adapted bacterial lipase
F van der Ent, BA Lund, L Svalberg, M Purg, G Chukwu, M Widersten, ...
Biochemistry 61 (10), 933-942, 2022
92022
Side‐Chain Interactions in d/l Peptide Nanotubes: Studies by Crystallography, NMR Spectroscopy and Molecular Dynamics
MR Silk, JR Price, B Mohanty, HKS Leiros, BA Lund, PE Thompson, ...
Chemistry–A European Journal 27 (58), 14489-14500, 2021
62021
Computational design of the temperature optimum of an enzyme reaction
F van der Ent, S Skagseth, BA Lund, J Sočan, JJ Griese, BO Brandsdal, ...
Science Advances 9 (26), eadi0963, 2023
42023
ThermoSlope: A software for determining thermodynamic parameters from single steady-state experiments
BA Lund, BO Brandsdal
Molecules 26 (23), 7155, 2021
32021
Accurate computation of thermodynamic activation parameters in the chorismate mutase reaction from empirical valence bond simulations
RS Wilkins, BA Lund, GV Isaksen, J Åqvist, BO Brandsdal
Journal of Chemical Theory and Computation 20 (1), 451-458, 2023
22023
Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times
MP Sowiński, S Gahlawat, BA Lund, AL Warnke, KH Hopmann, JE Lovett, ...
Communications Chemistry 6 (1), 111, 2023
22023
Regiodivergent Synthesis of 11H‐Indolo[3,2‐c]quinolines and Neocryptolepine from a Common Starting Material
KS Håheim, BA Lund, MO Sydnes
European Journal of Organic Chemistry 26 (13), e202300137, 2023
22023
The ambivalence of connexin43 Gap peptides in cardioprotection of the isolated heart against ischemic injury
AT Falck, BA Lund, D Johansen, T Lund, K Ytrehus
International Journal of Molecular Sciences 23 (17), 10197, 2022
12022
Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436
BA Lund, AM Thomassen, TJW Carlsen, HKS Leiros
Acta Crystallographica Section F: Structural Biology Communications 77 (9 …, 2021
12021
Biotech applications of protein kinase affinity interactions
BA Lund
Tromso, 2013
12013
Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening
EA FitzGerald, D Cederfelt, BA Lund, N Myers, H Zhang, D Dobritzsch, ...
RSC Medicinal Chemistry, 2024
2024
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