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Yong-Chen Lu
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LPS/TLR4 signal transduction pathway
YC Lu, WC Yeh, PS Ohashi
Cytokine 42 (2), 145-151, 2008
36832008
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
E Tran, S Turcotte, A Gros, PF Robbins, YC Lu, ME Dudley, ...
Science 344 (6184), 641-645, 2014
24242014
T-cell transfer therapy targeting mutant KRAS in cancer
E Tran, PF Robbins, YC Lu, TD Prickett, JJ Gartner, L Jia, A Pasetto, ...
New England Journal of Medicine 375 (23), 2255-2262, 2016
12532016
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
PF Robbins, YC Lu, M El-Gamil, YF Li, C Gross, J Gartner, JC Lin, JK Teer, ...
Nature medicine 19 (6), 747, 2013
11842013
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
N Zacharakis, H Chinnasamy, M Black, H Xu, YC Lu, Z Zheng, A Pasetto, ...
Nature medicine 24 (6), 724-730, 2018
7772018
Immunogenicity of somatic mutations in human gastrointestinal cancers
E Tran, M Ahmadzadeh, YC Lu, A Gros, S Turcotte, PF Robbins, ...
Science 350 (6266), 1387-1390, 2015
7502015
Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions
YC Lu, X Yao, JS Crystal, YF Li, M El-Gamil, C Gross, L Davis, ME Dudley, ...
Clinical Cancer Research 20 (13), 3401-3410, 2014
4402014
C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
NJ Chen, C Mirtsos, D Suh, YC Lu, WJ Lin, C McKerlie, T Lee, H Baribault, ...
Nature 446 (7132), 203-207, 2007
3212007
Pilot trial of adoptive transfer of chimeric antigen receptor–transduced T cells targeting EGFRvIII in patients with glioblastoma
SL Goff, RA Morgan, JC Yang, RM Sherry, PF Robbins, NP Restifo, ...
Journal of immunotherapy 42 (4), 126-135, 2019
2802019
Cancer immunotherapy targeting neoantigens
YC Lu, PF Robbins
Seminars in immunology 28 (1), 22-27, 2016
2792016
Treatment of patients with metastatic cancer using a major histocompatibility complex class II–restricted T-cell receptor targeting the cancer germline antigen MAGE-A3
YC Lu, LL Parker, T Lu, Z Zheng, MA Toomey, DE White, X Yao, YF Li, ...
Journal of Clinical Oncology 35 (29), 3322, 2017
2512017
Levels of peripheral CD4+FoxP3+ regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer
X Yao, M Ahmadzadeh, YC Lu, DJ Liewehr, ME Dudley, F Liu, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5688-5696, 2012
2292012
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
FJ Lowery, S Krishna, R Yossef, NB Parikh, PD Chatani, N Zacharakis, ...
Science 375 (6583), 877-884, 2022
2012022
Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression
YC Lu, X Yao, YF Li, M El-Gamil, ME Dudley, JC Yang, JR Almeida, ...
The Journal of Immunology 190 (12), 6034-6042, 2013
1682013
Differential role for c-Rel and C/EBPβ/δ in TLR-mediated induction of proinflammatory cytokines
YC Lu, I Kim, E Lye, F Shen, N Suzuki, S Suzuki, S Gerondakis, S Akira, ...
The Journal of Immunology 182 (11), 7212-7221, 2009
1382009
Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients
G Cafri, R Yossef, A Pasetto, DC Deniger, YC Lu, M Parkhurst, JJ Gartner, ...
Nature communications 10 (1), 449, 2019
1342019
Immunologic recognition of a shared p53 mutated neoantigen in a patient with metastatic colorectal cancer
W Lo, M Parkhurst, PF Robbins, E Tran, YC Lu, L Jia, JJ Gartner, ...
Cancer immunology research 7 (4), 534-543, 2019
1262019
An efficient single-cell RNA-seq approach to identify neoantigen-specific T cell receptors
YC Lu, Z Zheng, PF Robbins, E Tran, TD Prickett, JJ Gartner, YF Li, S Ray, ...
Molecular Therapy 26 (2), 379-389, 2018
972018
Adoptive cellular therapy with autologous tumor-infiltrating lymphocytes and T-cell receptor–engineered T cells targeting common p53 neoantigens in human solid tumors
SP Kim, NR Vale, N Zacharakis, S Krishna, Z Yu, B Gasmi, JJ Gartner, ...
Cancer immunology research 10 (8), 932-946, 2022
622022
Targeting neoantigens for cancer immunotherapy
YC Lu, PF Robbins
International immunology 28 (7), 365-370, 2016
552016
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