Philippe Lucarelli
Philippe Lucarelli
Botnar Research Centre for Child Health (BRCCH)
Dirección de correo verificada de brcch.org
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Downregulation of the TGFβ Pseudoreceptor BAMBI in Non–Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion
S Marwitz, S Depner, D Dvornikov, R Merkle, M Szczygieł, ...
Cancer research 76 (13), 3785-3801, 2016
492016
Dynamics and feedback loops in the transforming growth factor β signaling pathway
K Wegner, A Bachmann, JU Schad, P Lucarelli, S Sahle, P Nickel, ...
Biophysical chemistry 162, 22-34, 2012
312012
Resolving the combinatorial complexity of smad protein complex formation and its link to gene expression
P Lucarelli, M Schilling, C Kreutz, A Vlasov, ME Boehm, N Iwamoto, ...
Cell systems 6 (1), 75-89. e11, 2018
182018
Context-specific flow through the MEK/ERK module produces cell-and ligand-specific patterns of ERK single and double phosphorylation
N Iwamoto, LA D’Alessandro, S Depner, B Hahn, BA Kramer, P Lucarelli, ...
Sci. Signal. 9 (413), ra13-ra13, 2016
182016
Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers
N Raulf, P Lucarelli, S Thavaraj, S Brown, JM Vicencio, T Sauter, ...
European Journal of Cancer 102, 52-68, 2018
162018
Clinical update on head and neck cancer: molecular biology and ongoing challenges
TSMT Elham Alsahafi, Katheryn Begg, Ivano Amelio, Nina Raulf, Philippe Lucarelli
Cell Death & Diseasevolume 10 (540 (2019)), 2019
112019
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib
S Sobotta, A Raue, X Huang, J Vanlier, A Jünger, S Bohl, U Albrecht, ...
Frontiers in physiology 8, 775, 2017
72017
FALCON: a toolbox for the fast contextualization of logical networks
S De Landtsheer, P Trairatphisan, P Lucarelli, T Sauter
Bioinformatics 33 (21), 3431-3436, 2017
62017
Excemplify: a flexible template based solution, parsing and managing data in spreadsheets for experimentalists
L Shi, L Jong, U Wittig, P Lucarelli, M Stepath, S Mueller, LA D‘Alessandro, ...
Journal of integrative bioinformatics 10 (2), 58-70, 2013
42013
Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment
K Seip, K Jørgensen, MV Haselager, M Albrecht, MH Haugen, ...
Cancer letters 439, 1-13, 2018
22018
Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma
G Del Mistro, P Lucarelli, I Müller, S De Landtsheer, A Zinoveva, M Hutt, ...
NPJ systems biology and applications 4 (1), 1-12, 2018
12018
Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways
S De Landtsheer, P Lucarelli, T Sauter
Frontiers in Physiology 9, 550, 2018
12018
Cancer cells employ nuclear caspase-8 to overcome the p53-dependent G2/M checkpoint through cleavage of USP28
I Müller, E Strozyk, S Schindler, S Beissert, HZ Oo, T Sauter, P Lucarelli, ...
Molecular Cell, 2020
2020
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib
A Teufel, I Behrmann, JV González, J Timmer, M Schilling, U Klingmüller, ...
Systems Biology and Bioinformatics in Gastroenterology and Hepatology, 2020
2020
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ...
Parkinsonism & Related Disorders 67, 48-55, 2019
2019
Machine learning-assisted neurotoxicity prediction in human midbrain organoids
AS Monzel, K Hemmer, TK Mukendi, P Lucarelli, I Rosety, A Zagare, ...
bioRxiv, 774240, 2019
2019
Fat tissue specific microRNA expression in individuals with metabolic syndrome following lifestyle-induced weight loss: P100
R Biemann, P Lucarelli, N Thanh-Phuong, A Ginolhac, K Borucki, ...
Clinical Chemistry and Laboratory Medicine 55 (11), 2017
2017
Targetable nodes in fibroblast-supported melanoma cells that show resistance to BRAF inhibitors
K Seip, MV Haselager, K Jørgensen, M Albrecht, MH Haugen, ...
Cancer Research 77 (13 Supplement), 4329-4329, 2017
2017
Systembasierte Analyse von Wirkstoffresistenzen bei Melanom
P Lucarelli, S De Landtsheer, T Sauter
Germany, 2017
2017
Thermodynamically constrained averaging theory for cancer growth modelling
M Albrecht, G Sciumè, P Lucarelli, T Sauter
IFAC-PapersOnLine 49 (26), 289-294, 2016
2016
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Artículos 1–20