CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections GR Corey, MH Wilcox, GH Talbot, D Thye, D Friedland, T Baculik, ... Journal of antimicrobial chemotherapy 65 (suppl_4), iv41-iv51, 2010 | 220 | 2010 |
Cytotoxicity and bioaccumulation of heavy metals by ciliated protozoa isolated from urban wastewater treatment plants A Martín-González, S Díaz, S Borniquel, A Gallego, JC Gutiérrez Research in microbiology 157 (2), 108-118, 2006 | 151 | 2006 |
Small molecule targets TMED9 and promotes lysosomal degradation to reverse proteinopathy M Dvela-Levitt, M Kost-Alimova, M Emani, E Kohnert, R Thompson, ... Cell 178 (3), 521-535. e23, 2019 | 145 | 2019 |
Evaluation of heavy metal acute toxicity and bioaccumulation in soil ciliated protozoa S Díaz, A Martín-González, JC Gutiérrez Environment international 32 (6), 711-717, 2006 | 141 | 2006 |
Heavy metal whole-cell biosensors using eukaryotic microorganisms: an updated critical review JC Gutiérrez, F Amaro, A Martín-González Frontiers in microbiology 6, 127140, 2015 | 129 | 2015 |
Ciliates as a potential source of cellular and molecular biomarkers/biosensors for heavy metal pollution JC Gutiérrez, A Martín-González, S Díaz, R Ortega European journal of protistology 39 (4), 461-467, 2003 | 122 | 2003 |
Ciliate cryptobiosis: a microbial strategy against environmental starvation J Gutiérrez, S Callejas, S Borniquel, L Benítez, A Martín-González International microbiology 4, 151-157, 2001 | 116 | 2001 |
Biomass stabilization in the anaerobic digestion of wastewater sludges C Arnaiz, JC Gutierrez, J Lebrato Bioresource technology 97 (10), 1179-1184, 2006 | 114 | 2006 |
Tetrahymena Metallothioneins Fall into Two Discrete Subfamilies S Diaz, F Amaro, D Rico, V Campos, L Benitez, A Martin-Gonzalez, ... PLoS One 2 (3), e291, 2007 | 112 | 2007 |
Whole‐cell biosensors for detection of heavy metal ions in environmental samples based on metallothionein promoters from Tetrahymena thermophila F Amaro, AP Turkewitz, A Martín‐González, JC Gutiérrez Microbial biotechnology 4 (4), 513-522, 2011 | 111 | 2011 |
Heavy metals generate reactive oxygen species in terrestrial and aquatic ciliated protozoa D Rico, A Martín-González, S Díaz, P de Lucas, JC Gutiérrez Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2009 | 97 | 2009 |
Flow cytometry assessment of cytotoxicity and reactive oxygen species generation by single and binary mixtures of cadmium, zinc and copper on populations of the ciliated … A Gallego, A Martín-González, R Ortega, JC Gutiérrez Chemosphere 68 (4), 647-661, 2007 | 89 | 2007 |
Towards a generalized model of encystment (cryptobiosis) in ciliates: a review and a hypothesis JC Gutiérrez, A Martin-Gonzalez, T Matsusaka BioSystems 24 (1), 17-24, 1990 | 78 | 1990 |
Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study B Gutiérrez-Gutiérrez, MD Del Toro, AM Borobia, A Carcas, I Jarrín, ... The Lancet infectious diseases 21 (6), 783-792, 2021 | 77 | 2021 |
Ciliate metallothioneins: unique microbial eukaryotic heavy-metal-binder molecules JC Gutiérrez, F Amaro, S Díaz, P De Francisco, LL Cubas, ... JBIC Journal of Biological Inorganic Chemistry 16, 1025-1034, 2011 | 67 | 2011 |
From heavy metal‐binders to biosensors: Ciliate metallothioneins discussed JC Gutiérrez, F Amaro, A Martín‐González BioEssays 31 (7), 805-816, 2009 | 63 | 2009 |
Functional GFP-metallothionein fusion protein from Tetrahymena thermophila: a potential whole-cell biosensor for monitoring heavy metal pollution and a cell … F Amaro, AP Turkewitz, A Martín-González, JC Gutiérrez Biometals 27, 195-205, 2014 | 56 | 2014 |
Metallic nanoparticles—friends or foes in the battle against antibiotic-resistant bacteria? F Amaro, Á Morón, S Díaz, A Martín-González, JC Gutiérrez Microorganisms 9 (2), 364, 2021 | 55 | 2021 |
Ultrastructural alterations in ciliated protozoa under heavy metal exposure A Martín-González, S Borniquel, S Díaz, R Ortega, JC Gutiérrez Cell biology international 29 (2), 119-126, 2005 | 50 | 2005 |
Stress and Protists: No life without stress V Slaveykova, B Sonntag, JC Gutiérrez European journal of protistology 55, 39-49, 2016 | 48 | 2016 |