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Yijuang Chern
Yijuang Chern
Dirección de correo verificada de ibms.sinica.edu.tw
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Aspects of the general biology of adenosine A2A signaling
BB Fredholm, Y Chern, R Franco, M Sitkovsky
Progress in neurobiology 83 (5), 263-276, 2007
2272007
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
HY Hsiao, YC Chen, HM Chen, PH Tu, Y Chern
Human molecular genetics 22 (9), 1826-1842, 2013
1942013
CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model
SY Chou, YC Lee, HM Chen, MC Chiang, HL Lai, HH Chang, YC Wu, ...
Journal of neurochemistry 93 (2), 310-320, 2005
1882005
Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease
TC Ju, HM Chen, JT Lin, CP Chang, WC Chang, JJ Kang, CP Sun, ...
Journal of Cell Biology 194 (2), 209-227, 2011
1802011
Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response
HL Lai, TH Yang, RO Messing, YH Ching, SC Lin, Y Chern
Journal of Biological Chemistry 272 (8), 4970-4977, 1997
1561997
Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism
WC Shen, HY Li, GC Chen, Y Chern, P Tu
Autophagy 11 (4), 685-700, 2015
1302015
Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models
YT Lin, Y Chern, CKJ Shen, HL Wen, YC Chang, H Li, TH Cheng, ...
PloS one 6 (8), e22924, 2011
1182011
Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease
JJ Siew, HM Chen, HY Chen, HL Chen, CM Chen, BW Soong, YR Wu, ...
Nature communications 10 (1), 1-18, 2019
1152019
Activation of protein kinase A and atypical protein kinase C by A2A adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells
NK Huang, YW Lin, CL Huang, RO Messing, Y Chern
Journal of Biological Chemistry 276 (17), 13838-13846, 2001
1152001
Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage …
HC Cheng, HM Shih, Y Chern
Journal of Biological Chemistry 277 (37), 33930-33942, 2002
1122002
Adenosine receptor neurobiology: overview
JF Chen, C Lee, Y Chern
International review of neurobiology 119, 1-49, 2014
1092014
Regulation of adenylyl cyclase in the central nervous system
Y Chern
Cellular signalling 12 (4), 195-204, 2000
1092000
Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells.
Y Chern, HL Lai, JC Fong, Y Liang
Molecular pharmacology 44 (5), 950-958, 1993
1061993
Dysregulation of C/EBPα by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease
MC Chiang, HM Chen, YH Lee, HH Chang, YC Wu, BW Soong, CM Chen, ...
Human molecular genetics 16 (5), 483-498, 2007
1032007
Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease
HY Hsiao, FL Chiu, CM Chen, YR Wu, HM Chen, YC Chen, HC Kuo, ...
Human molecular genetics 23 (16), 4328-4344, 2014
1012014
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes
SY Chou, JY Weng, HL Lai, F Liao, SH Sun, PH Tu, DW Dickson, Y Chern
Journal of Neuroscience 28 (13), 3277-3290, 2008
1012008
Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma
MC Chiang, CM Chen, MR Lee, HW Chen, HM Chen, YS Wu, CH Hung, ...
Human molecular genetics 19 (20), 4043-4058, 2010
1002010
PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease
MC Chiang, Y Chern, RN Huang
Neurobiology of disease 45 (1), 322-328, 2012
972012
Spt4 is selectively required for transcription of extended trinucleotide repeats
CR Liu, CR Chang, Y Chern, TH Wang, WC Hsieh, WC Shen, CY Chang, ...
Cell 148 (4), 690-701, 2012
942012
Neurovascular abnormalities in humans and mice with Huntington's disease
CY Lin, YH Hsu, MH Lin, TH Yang, HM Chen, YC Chen, HY Hsiao, ...
Experimental neurology 250, 20-30, 2013
912013
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Artículos 1–20