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Matthias Pauthner
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Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
JG Jardine, T Ota, D Sok, M Pauthner, DW Kulp, O Kalyuzhniy, PD Skog, ...
Science 349 (6244), 156-161, 2015
4182015
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
D Sok, MJ van Gils, M Pauthner, JP Julien, KL Saye-Francisco, J Hsueh, ...
Proceedings of the National Academy of Sciences 111 (49), 17624-17629, 2014
3682014
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ...
Cell 177 (5), 1153-1171. e28, 2019
2942019
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches
M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ...
Immunity 46 (6), 1073-1088. e6, 2017
2932017
A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure
JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ...
Immunity 46 (4), 690-702, 2017
2322017
Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies
LE McCoy, MJ van Gils, G Ozorowski, T Messmer, B Briney, JE Voss, ...
Cell reports 16 (9), 2327-2338, 2016
2312016
Global site-specific N-glycosylation analysis of HIV envelope glycoprotein
L Cao, JK Diedrich, DW Kulp, M Pauthner, L He, SKR Park, D Sok, CY Su, ...
Nature communications 8 (1), 14954, 2017
2232017
Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization
M Bianchi, HL Turner, B Nogal, CA Cottrell, D Oyen, M Pauthner, ...
Immunity 49 (2), 288-300. e8, 2018
1732018
Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice
D Sok, B Briney, JG Jardine, DW Kulp, S Menis, M Pauthner, A Wood, ...
Science 353 (6307), 1557-1560, 2016
1642016
Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer
C Havenar-Daughton, DG Carnathan, AT de la Peña, M Pauthner, ...
Cell reports 17 (9), 2195-2209, 2016
1572016
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
MJ Van Gils, TLGM Van Den Kerkhof, G Ozorowski, CA Cottrell, D Sok, ...
Nature microbiology 2 (2), 1-10, 2016
1432016
A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans
D Sok, M Pauthner, B Briney, JH Lee, KL Saye-Francisco, J Hsueh, ...
Immunity 45 (1), 31-45, 2016
1422016
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding
DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ...
Nature communications 8 (1), 1655, 2017
1402017
Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers
MG Pauthner, JP Nkolola, C Havenar-Daughton, B Murrell, SM Reiss, ...
Immunity 50 (1), 241-252. e6, 2019
1392019
Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design
JG Jardine, D Sok, JP Julien, B Briney, A Sarkar, CH Liang, EA Scherer, ...
PLoS pathogens 12 (8), e1005815, 2016
1272016
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
L Cao, M Pauthner, R Andrabi, K Rantalainen, Z Berndsen, JK Diedrich, ...
Nature communications 9 (1), 3693, 2018
1262018
CodY orchestrates the expression of virulence determinants in emetic Bacillus cereus by impacting key regulatory circuits
E Frenzel, V Doll, M Pauthner, G Lücking, S Scherer, M Ehling‐Schulz
Molecular microbiology 85 (1), 67-88, 2012
882012
Global site-specific analysis of glycoprotein N-glycan processing
L Cao, JK Diedrich, Y Ma, N Wang, M Pauthner, SKR Park, CM Delahunty, ...
Nature protocols 13 (6), 1196-1212, 2018
812018
A meta-analysis of passive immunization studies shows that serum-neutralizing antibody titer associates with protection against SHIV challenge
A Pegu, B Borate, Y Huang, MG Pauthner, AJ Hessell, B Julg, ...
Cell host & microbe 26 (3), 336-346. e3, 2019
792019
Ebola virus transmission initiated by relapse of systemic Ebola virus disease
P Mbala-Kingebeni, C Pratt, M Mutafali-Ruffin, MG Pauthner, F Bile, ...
New England Journal of Medicine 384 (13), 1240-1247, 2021
782021
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