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Jeffrey Ackroyd
Jeffrey Ackroyd
Verified email at mdanderson.org
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Cited by
Year
An inhibitor of oxidative phosphorylation exploits cancer vulnerability
JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ...
Nature medicine 24 (7), 1036-1046, 2018
7122018
Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer
P Hou, A Kapoor, Q Zhang, J Li, CJ Wu, J Li, Z Lan, M Tang, X Ma, ...
Cancer discovery 10 (7), 1058-1077, 2020
962020
USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation
P Hou, X Ma, Q Zhang, CJ Wu, W Liao, J Li, H Wang, J Zhao, X Zhou, ...
Genes & development 33 (19-20), 1361-1366, 2019
732019
An enolase inhibitor for the targeted treatment of ENO1-deleted cancers
YH Lin, N Satani, N Hammoudi, VC Yan, Y Barekatain, S Khadka, ...
Nature metabolism 2 (12), 1413-1426, 2020
472020
Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools
A Bianchi-Smiraglia, A Bagati, EE Fink, S Moparthy, JA Wawrzyniak, ...
Oncogene 36 (1), 84-96, 2017
402017
Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity
A Bianchi-Smiraglia, JA Wawrzyniak, A Bagati, EK Marvin, J Ackroyd, ...
Cell Death & Differentiation 22 (11), 1858-1864, 2015
372015
Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine
Y Barekatain, JJ Ackroyd, VC Yan, S Khadka, L Wang, KC Chen, ...
Nature communications 12 (1), 4228, 2021
262021
Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo
ST Gammon, F Pisaneschi, ML Bandi, MG Smith, Y Sun, Y Rao, F Muller, ...
Cells 8 (12), 1487, 2019
222019
Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity
B Ladd, JJ Ackroyd, JK Hicks, CE Canman, SA Flanagan, DS Shewach
DNA repair 12 (12), 1114-1121, 2013
182013
Eradication of ENO1-deleted Glioblastoma through Collateral Lethality
YH Lin, N Satani, N Hammoudi, JJ Ackroyd, S Khadka, VC Yan, ...
BioRxiv, 331538, 2018
162018
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma
S Khadka, K Arthur, Y Barekatain, E Behr, M Washington, J Ackroyd, ...
Cancer & Metabolism 9 (1), 27, 2021
122021
Pharmacokinetics of orally administered GS-441524 in dogs
VC Yan, CD Pham, MJ Yan, AJ Yan, S Khadka, K Arthur, JJ Ackroyd, ...
bioRxiv, 2021
102021
Drug metabolism and homologous recombination repair in radiosensitization with gemcitabine
MM Im, SA Flanagan, JJ Ackroyd, DS Shewach
Radiation research 183 (1), 114-123, 2015
102015
Late DNA damage mediated by homologous recombination repair results in radiosensitization with gemcitabine
MM Im, SA Flanagan, JJ Ackroyd, B Knapp, A Kramer, DS Shewach
Radiation Research 186 (5), 466-477, 2016
82016
Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 …
TL Pulliam, D Awad, JJ Han, MM Murray, JJ Ackroyd, P Goli, JS Oakhill, ...
Cells 11 (12), 1890, 2022
72022
Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers
VC Yan, CD Pham, ES Ballato, KL Yang, K Arthur, S Khadka, ...
Journal of Medicinal Chemistry 65 (20), 13813-13832, 2022
32022
Robust detection of oncometabolic aberrations by 1H–13C heteronuclear single quantum correlation in intact biological specimens
Y Barekatain, VC Yan, K Arthur, JJ Ackroyd, S Khadka, J De Groot, ...
Communications Biology 3 (1), 328, 2020
32020
Methylthioadenosine is Not Dramatically Elevated in MTAP-Homozygous Deleted Primary Glioblastomas
Y Barekatain, VC Yan, JJ Ackroyd, AH Poral, T Tran, DK Georgiou, ...
bioRxiv, 769885, 2019
12019
Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
D Awad, PHA Cao, TL Pulliam, M Spradlin, E Subramani, TV Tellman, ...
Cancer Research 84 (5), 703-724, 2024
2024
Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism
S Khadka, YH Lin, J Ackroyd, YA Chen, Y Sheng, W Qian, S Guo, Y Chen, ...
bioRxiv, 2023
2023
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