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Ignacio Gonzalez-Garcia
Ignacio Gonzalez-Garcia
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
In vitro–in vivo correlations: general concepts, methodologies and regulatory applications
I González-García, V Mangas-Sanjuán, M Merino-Sanjuán, M Bermejo
Drug development and industrial pharmacy 41 (12), 1935-1947, 2015
412015
Variability of permeability estimation from different protocols of subculture and transport experiments in cell monolayers
D Oltra-Noguera, V Mangas-Sanjuan, A Centelles-Sangüesa, ...
Journal of Pharmacological and Toxicological Methods 71, 21-32, 2015
402015
Safety and clinical activity of MEDI1873, a novel GITR agonist, in advanced solid tumors
AS Balmanoukian, JR Infante, R Aljumaily, A Naing, AV Chintakuntlawar, ...
Clinical Cancer Research 26 (23), 6196-6203, 2020
382020
A systems pharmacology model for inflammatory bowel disease
V Balbas-Martinez, L Ruiz-Cerdá, I Irurzun-Arana, I Gonzalez-Garcia, ...
PLoS One 13 (3), e0192949, 2018
362018
Towards patient stratification and treatment in the autoimmune disease lupus erythematosus using a systems pharmacology approach
ML Ruiz-Cerdá, I Irurzun-Arana, I González-Garcia, C Hu, H Zhou, ...
European Journal of Pharmaceutical Sciences 94, 46-58, 2016
212016
IVIVC approach based on carbamazepine bioequivalence studies combination
I González-García, V Mangas-Sanjuan, M Merino-Sanjuán, ...
Die Pharmazie-An International Journal of Pharmaceutical Sciences 72 (8 …, 2017
132017
Population pharmacokinetic model of lithium and drug compliance assessment
I Pérez-Castelló, V Mangas-Sanjuan, I González-García, ...
European Neuropsychopharmacology 26 (12), 1868-1876, 2016
112016
A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development
A Ruiz-Garcia, P Baverel, D Bottino, M Dolton, Y Feng, I González-García, ...
Journal of Pharmacokinetics and Pharmacodynamics 50 (3), 147-172, 2023
102023
Association of circulating protein biomarkers with clinical outcomes of durvalumab in head and neck squamous cell carcinoma
R Arends, X Guo, PG Baverel, I González-García, J Xie, N Morsli, ...
Oncoimmunology 10 (1), 1898104, 2021
102021
Two-step in vitro-in vivo correlations: Deconvolution and convolution methods, which one gives the best predictability? Comparison with one-step approach
B Sánchez-Dengra, I González-García, M González-Álvarez, ...
European Journal of Pharmaceutics and Biopharmaceutics 158, 185-197, 2021
82021
Early predictions of response and survival from a tumor dynamics model in patients with recurrent, metastatic head and neck squamous cell carcinoma treated with immunotherapy
I González‐García, V Pierre, VFS Dubois, N Morsli, S Spencer, ...
CPT: Pharmacometrics & Systems Pharmacology 10 (3), 230-240, 2021
62021
Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles of a controlled release formulation
I González-García, A García-Arieta, M Merino-Sanjuan, ...
European Journal of Pharmaceutical Sciences 119, 200-207, 2018
42018
Imputing Biomarker Status from RWE Datasets—A Comparative Study
C Traynor, T Sahota, H Tomkinson, I Gonzalez-Garcia, N Evans, ...
Journal of Personalized Medicine 11 (12), 1356, 2021
22021
Pharmacokinetic-pharmacodynamic modelling of systemic IL13 blockade by monoclonal antibody therapy: a free assay disguised as total
J Hood, I González-García, N White, L Marshall, VFS Dubois, P Vicini, ...
Pharmaceutics 13 (4), 519, 2021
22021
Overall survival modeling and association with serum biomarkers in durvalumab-treated patients with head and neck cancer.
V Pierre, X Guo, I Gonzalez-Garcia, N Morsli, AJ Yovine, W Li, R Narwal, ...
Journal of Clinical Oncology 38 (15_suppl), 6549-6549, 2020
22020
Systems Pharmacology model for Inflammatory Bowel Disease (IBD)
V Balbas-Martinez, L Ruiz-Cerdá, I Irurzun-Arana, I González-García, ...
International Conference on Systems Biology, 2016
22016
Towards a Survival Risk Prediction Model for Metastatic NSCLC Patients on Durvalumab Using Whole-Lung CT Radiomics
KA Patwardhan, H RaviPrakash, N Nikolaou, I Gonzalez-Garcia, ...
bioRxiv, 2024.02. 01.578458, 2024
2024
EARLY PREDICTIONS OF RESPONSE AND SURVIVAL FROM A TUMOR GROWTH INHIBITION (TGI) MODEL IN HEAD AND NECK SQUAMOUS-CELL CARCINOMA (HNSCC) PATIENTS TREATED WITH DURVALUMAB.
I Gonzalez-Garcia, V Pierre, V Dubois, N Morsli, S Spencer, P Baverel, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S119-S120, 2020
2020
Validación de procedimientos poblacionales mediante convolución para el establecimiento de corelaciones in vitro-in vivo
IG Garcia
Universitat de València, 2018
2018
Building an inflammatory bowel disease network, a systems pharmacology approach
I Gonzalez-Garcia, I Irurzun-Arana, L Ruiz-Cerda, C Hu, H Zhou, ...
6th American conference on Pharmacometrics (ACoP-6) 42 (suppl. 1), S83-S84, 2015
2015
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