José M. Padrón
José M. Padrón
BioLab, IUBO-AG & ITB, Universidad de La Laguna (RoR 01r9z8p25)
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Enantiospecific synthesis of α-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated α-amino acids
JM Padrón, G Kokotos, T Martín, T Markidis, WA Gibbons, VS Martín
Tetrahedron: Asymmetry 9 (19), 3381-3394, 1998
A general approach to the asymmetric synthesis of unsaturated lipidic α-amino acids. The first synthesis of α-aminoarachidonic acid
G Kokotos, JM Padron, T Martín, WA Gibbons, VS Martin
The Journal of Organic Chemistry 63 (11), 3741-3744, 1998
The multilayered postconfluent cell culture as a model for drug screening
JM Padrón, CL van der Wilt, K Smid, E Smitskamp-Wilms, HHJ Backus, ...
Critical Reviews in Oncology/Hematology 36 (2), 141-157, 2000
Folate depletion increases sensitivity of solid tumor cell lines to 5‐fluorouracil and antifolates
HHJ Backus, HM Pinedo, D Wouters, JM Padron, N Molders, ...
International Journal of Cancer 87 (6), 771-778, 2000
Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol
EL Bonifazi, C Ríos-Luci, LG León, G Burton, JM Padrón, RI Misico
Bioorganic & Medicinal Chemistry 18 (7), 2621-2630, 2010
Prins‐type synthesis and SAR study of cytotoxic alkyl chloro dihydropyrans
PO Miranda, JM Padron, JI Padrón, J Villar, VS Martín
ChemMedChem 1 (3), 323-329, 2006
Enantioselective transport by a steroidal guanidinium receptor
B Baragaña, AG Blackburn, P Breccia, AP Davis, J De Mendoza, ...
Chemistry–A European Journal 8 (13), 2931-2936, 2002
Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines
IC Guerrero, LS Andrés, LG León, RP Machín, JM Padrón, JG Luis, ...
Journal of Natural Products 69 (12), 1803-1805, 2006
Stereocontrolled synthesis of cyclic ethers by intramolecular hetero-Michael addition. 5. Synthesis of all diastereoisomers of 2,3,5,6-tetrasubstituted tetrahydropyrans
JM Betancort, VS Martin, JM Padron, JM Palazon, MA Ramirez, MA Soler
The Journal of Organic Chemistry 62 (14), 4570-4583, 1997
Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand
CM Santos, S Cabrera, C Ríos-Luci, JM Padrón, IL Solera, AG Quiroga, ...
Dalton Transactions 42 (37), 13343-13348, 2013
Catalytically generated ferrocene-containing guanidines as efficient precursors for new redox-active heterometallic platinum(II) complexes with anticancer activity
D Nieto, S Bruña, AM González-Vadillo, J Perles, F Carrillo-Hermosilla, ...
Organometallics 34 (22), 5407-5417, 2015
Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines
S Rudys, C Ríos-Luci, E Pérez-Roth, I Cikotiene, JM Padrón
Bioorganic & Medicinal Chemistry Letters 20 (5), 1504-1506, 2010
Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol
CR Pungitore, LG León, C García, VS Martín, CE Tonn, JM Padrón
Bioorganic & Medicinal Chemistry Letters 17 (5), 1332-1335, 2007
Molecular simplification in bioactive molecules: formal synthesis of (+)-muconin
FR Pinacho Crisóstomo, R Carrillo, LG León, T Martín, JM Padrón, ...
The Journal of Organic Chemistry 71 (6), 2339-2345, 2006
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
JM Roldán-Peña, D Alejandre-Ramos, Ó López, I Maya, I Lagunes, ...
European Journal of Medicinal Chemistry 138, 761-773, 2017
Stereocontrolled synthesis of cyclic ethers by intramolecular hetero-Michael addition. 6. A computational study of the annelation to 2,3-disubstituted tetrahydropyrans
MA Ramirez, JM Padron, JM Palazon, VS Martin
The Journal of Organic Chemistry 62 (14), 4584-4590, 1997
Antiproliferative activity of withanolides against human breast cancer cell lines
RP Machin, AS Veleiro, VE Nicotra, JC Oberti, J M. Padrón
Journal of Natural Products 73 (5), 966-968, 2010
β-Lapachone analogs with enhanced antiproliferative activity
C Ríos-Luci, EL Bonifazi, LG León, JC Montero, G Burton, A Pandiella, ...
European Journal of Medicinal Chemistry 53, 264-274, 2012
Sphingolipids in anticancer therapy
JM Padrón
Current Medicinal Chemistry 13 (7), 755-770, 2006
The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells
OJ Donadel, T Martín, VS Martín, J Villar, JM Padrón
Bioorganic & Medicinal Chemistry Letters 15 (15), 3536-3539, 2005
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