Olivier Sperandio
Olivier Sperandio
Pasteur Institute - Inserm
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Cited by
Cited by
Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
S Pérot, O Sperandio, MA Miteva, AC Camproux, BO Villoutreix
Drug discovery today 15 (15-16), 656-667, 2010
FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects
D Lagorce, O Sperandio, H Galons, MA Miteva, BO Villoutreix
BMC bioinformatics 9, 1-9, 2008
FAF-Drugs3: a web server for compound property calculation and chemical library design
D Lagorce, O Sperandio, JB Baell, MA Miteva, BO Villoutreix
Nucleic acids research 43 (W1), W200-W207, 2015
Rationalizing the chemical space of protein–protein interaction inhibitors
O Sperandio, CH Reynès, AC Camproux, BO Villoutreix
Drug discovery today 15 (5-6), 220-229, 2010
MTiOpenScreen: a web server for structure-based virtual screening
CM Labbé, J Rey, D Lagorce, M Vavruša, J Becot, O Sperandio, ...
Nucleic acids research 43 (W1), W448-W454, 2015
Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo
S Attoub, O Sperandio, H Raza, K Arafat, S Al‐Salam, MA Al Sultan, ...
Fundamental & clinical pharmacology 27 (5), 557-569, 2013
Thermoresponsive complex coacervate‐based underwater adhesive
M Dompé, FJ Cedano‐Serrano, O Heckert, N van den Heuvel, ...
Advanced Materials 31 (21), 1808179, 2019
New machine learning and physics-based scoring functions for drug discovery
IA Guedes, AMS Barreto, D Marinho, E Krempser, MA Kuenemann, ...
Scientific reports 11 (1), 3198, 2021
Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods
C Reynès, H Host, AC Camproux, G Laconde, F Leroux, A Mazars, ...
PLoS computational biology 6 (3), e1000695, 2010
Free resources to assist structure-based virtual ligand screening experiments
BO Villoutreix, N Renault, D Lagorce, O Sperandio, M Montes, MA Miteva
Current Protein and Peptide Science 8 (4), 381-411, 2007
Drug‐Like Protein Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology
BO Villoutreix, MA Kuenemann, JL Poyet, H Bruzzoni‐Giovanelli, ...
Molecular informatics 33 (6‐7), 414-437, 2014
iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein–protein interactions
CM Labbé, G Laconde, MA Kuenemann, BO Villoutreix, O Sperandio
Drug discovery today 18 (19-20), 958-968, 2013
The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections
D Lagorce, J Maupetit, J Baell, O Sperandio, P Tufféry, MA Miteva, ...
Bioinformatics 27 (14), 2018-2020, 2011
In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics
BO Villoutreix, K Bastard, O Sperandio, R Fahraeus, JL Poyet, F Calvo, ...
Current Pharmaceutical Biotechnology 9 (2), 103-122, 2008
One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade
BO Villoutreix, D Lagorce, CM Labbe, O Sperandio, MA Miteva
Drug Discovery Today 18 (21-22), 1081-1089, 2013
A leap into the chemical space of protein-protein interaction inhibitors
B O Villoutreix, C M Labbe, D Lagorce, G Laconde, O Sperandio
Current pharmaceutical design 18 (30), 4648-4667, 2012
How to choose relevant multiple receptor conformations for virtual screening: a test case of Cdk2 and normal mode analysis
O Sperandio, L Mouawad, E Pinto, BO Villoutreix, D Perahia, MA Miteva
European Biophysics Journal 39, 1365-1372, 2010
Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking …
B Villemagne, M Flipo, N Blondiaux, C Crauste, S Malaquin, F Leroux, ...
Journal of medicinal chemistry 57 (11), 4876-4888, 2014
Receptor-based computational screening of compound databases: the main docking-scoring engines
O Sperandio, MA Miteva, F Delfaud, BO Villoutreix
Current Protein and Peptide Science 7 (5), 369-393, 2006
In silico design of low molecular weight protein–protein interaction inhibitors: Overall concept and recent advances
MA Kuenemann, O Sperandio, CM Labbé, D Lagorce, MA Miteva, ...
Progress in biophysics and molecular biology 119 (1), 20-32, 2015
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