| Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal … AR Blaazer, AK Singh, E De Heuvel, E Edink, KM Orrling, JJN Veerman, ... Journal of medicinal chemistry 61 (9), 3870-3888, 2018 | 40 | 2018 |
| Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγ K Nikhil, S Sharan, AK Singh, A Chakraborty, P Roy PLoS One 9 (8), e104592, 2014 | 31 | 2014 |
| Structure and sialyllactose binding of the carboxy-terminal head domain of the fibre from a siadenovirus, turkey adenovirus 3 AK Singh, MA Berbis, MZ Ballmann, M Kilcoyne, M Menendez, ... PloS one 10 (9), e0139339, 2015 | 27 | 2015 |
| Structure of a reptilian adenovirus reveals a phage tailspike fold stabilizing a vertebrate virus capsid R Menéndez-Conejero, TH Nguyen, AK Singh, GN Condezo, ... Structure 25 (10), 1562-1573. e5, 2017 | 21 | 2017 |
| Some of the most interesting CASP 11 targets through the eyes of their authors A Kryshtafovych, J Moult, A Baslé, A Burgin, TK Craig, RA Edwards, ... Proteins: Structure, Function, and Bioinformatics 84, 34-50, 2016 | 21 | 2016 |
| Crystal structure of the fibre head domain of the atadenovirus snake adenovirus 1 AK Singh, R Menendez-Conejero, C San Martín, MJ van Raaij PLoS One 9 (12), e114373, 2014 | 18 | 2014 |
| Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors E De Heuvel, AK Singh, E Edink, T van der Meer, M van der Woude, ... Bioorganic & medicinal chemistry 27 (18), 3998-4012, 2019 | 16 | 2019 |
| Chlamydial virulence factor TarP mimics talin to disrupt the talin‐vinculin complex AJ Whitewood, AK Singh, DG Brown, BT Goult FEBS letters 592 (10), 1751-1760, 2018 | 16 | 2018 |
| Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2) Bioorganic & Medicinal Chemistry 27 (18), 4013-4029, 2019 | 14 | 2019 |
| Talin rod domain–containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation AR Cowell, G Jacquemet, AK Singh, L Varela, AS Nylund, YC Ammon, ... Journal of Cell Biology 220 (9), e202005214, 2021 | 12 | 2021 |
| Target highlights from the first post‐PSI CASP experiment (CASP12, May–August 2016) A Kryshtafovych, R Albrecht, A Basle, P Bule, AT Caputo, AL Carvalho, ... Proteins: Structure, Function, and Bioinformatics 86, 27-50, 2018 | 11 | 2018 |
| Crystallization of the C-terminal head domain of the fibre protein from a siadenovirus, turkey adenovirus 3 AK Singh, MZ Ballmann, M Benkő, B Harrach, MJ van Raaij Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 11 | 2013 |
| Insights into HIV-1 reverse transcriptase (RT) inhibition and drug resistance from thirty years of structural studies AK Singh, K Das Viruses 14 (5), 1027, 2022 | 9 | 2022 |
| Development of a Novel SPR Assay to Study CXCR4–Ligand Interactions A Boonen, AK Singh, AV Hout, K Das, TV Loy, S Noppen, D Schols Biosensors 10 (10), 150, 2020 | 9 | 2020 |
| Lead optimization of phthalazinone phosphodiesterase inhibitors as novel antitrypanosomal compounds IG Salado, AK Singh, C Moreno-Cinos, G Sakaine, M Siderius, ... Journal of medicinal chemistry 63 (7), 3485-3507, 2020 | 9 | 2020 |
| Crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus TH Nguyen, MZ Vidovszky, MZ Ballmann, M Sanz-Gaitero, AK Singh, ... Virology journal 12, 1-12, 2015 | 8 | 2015 |
| Cañada, FJ; Jiménez-Barbero, J.; Benko, M.; et al. Structure and sialyllactose binding of the carboxy-terminal head domain of the fibre from a siadenovirus, Turkey adenovirus 3 AK Singh, MÁ Berbís, MZ Ballmann, M Kilcoyne, M Menendez, ... PLoS One 10, e0139339, 2015 | 8 | 2015 |
| Crystallization of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34 M Granell, M Namura, S Alvira, C Garcia-Doval, AK Singh, I Gutsche, ... Acta Crystallographica Section F: Structural Biology Communications 70 (7 …, 2014 | 8 | 2014 |
| Crystallization of the C-terminal domain of the fibre protein from snake adenovirus 1, an atadenovirus AK Singh, R Menéndez-Conejero, C San Martin, MJ van Raaij Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 8 | 2013 |
| Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket–targeting P-pocket by fragment screening AK Singh, SE Martinez, W Gu, H Nguyen, D Schols, P Herdewijn, ... Nature communications 12 (1), 7127, 2021 | 7 | 2021 |
Mark van RaaijCentro Nacional de Biotecnologica CSICVerified email at cnb.csic.es
