YAP1 regulates OCT4 activity and SOX2 expression to facilitate self‐renewal and vascular mimicry of stem‐like cells N Bora‐Singhal, J Nguyen, C Schaal, D Perumal, S Singh, D Coppola, ... Stem cells 33 (6), 1705-1718, 2015 | 158 | 2015 |
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, ... Cell stem cell 20 (3), 315-328. e7, 2017 | 140 | 2017 |
Gli1-mediated regulation of Sox2 facilitates self-renewal of stem-like cells and confers resistance to EGFR inhibitors in non–small cell lung cancer N Bora-Singhal, D Perumal, J Nguyen, S Chellappan Neoplasia 17 (7), 538-551, 2015 | 129 | 2015 |
Mutation-derived neoantigen-specific T-cell responses in multiple myeloma D Perumal, N Imai, A Laganą, J Finnigan, D Melnekoff, VV Leshchenko, ... Clinical Cancer Research 26 (2), 450-464, 2020 | 72 | 2020 |
Differential genome analyses of metabolic enzymes in Pseudomonas aeruginosa for drug target identification D Perumal, CS Lim, KR Sakharkar, MK Sakharkar In silico biology 7 (4-5), 453-465, 2007 | 72 | 2007 |
Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma A Laganą, D Perumal, D Melnekoff, B Readhead, BA Kidd, V Leshchenko, ... Leukemia, 1-11, 2017 | 70 | 2017 |
A novel five gene signature derived from stem-like side population cells predicts overall and recurrence-free survival in NSCLC D Perumal, S Singh, SJ Yoder, GC Bloom, SP Chellappan Public Library of Science 7 (8), e43589, 2012 | 69 | 2012 |
High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma PY Kuo, VV Leshchenko, MJ Fazzari, D Perumal, T Gellen, T He, J Iqbal, ... Oncogene 34 (10), 1231-1240, 2015 | 64 | 2015 |
Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma MCJ Ma, S Tadros, A Bouska, T Heavican, H Yang, Q Deng, D Moore, ... Haematologica 107 (3), 690, 2022 | 50 | 2022 |
SOX11 augments BCR signaling to drive MCL-like tumor development PY Kuo, SS Jatiani, AH Rahman, D Edwards, Z Jiang, K Ahr, D Perumal, ... Blood, The Journal of the American Society of Hematology 131 (20), 2247-2255, 2018 | 48 | 2018 |
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner S Nair, N Bora-Singhal, D Perumal, S Chellappan Molecular cancer 13, 1-16, 2014 | 45 | 2014 |
Nicotinic acetylcholine receptors induce c-Kit ligand/stem cell factor and promote stemness in an ARRB1/β-arrestin-1 dependent manner in NSCLC D Perumal, S Pillai, J Nguyen, C Schaal, D Coppola, SP Chellappan Oncotarget 5 (21), 10486, 2014 | 45 | 2014 |
A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma A Chari, HJ Cho, A Dhadwal, G Morgan, L La, K Zarychta, D Catamero, ... Blood advances 1 (19), 1575-1583, 2017 | 39 | 2017 |
Precision medicine for relapsed multiple myeloma on the basis of an integrative multiomics approach A Laganą, I Beno, D Melnekoff, V Leshchenko, D Madduri, D Ramdas, ... JCO precision oncology 2, 1-17, 2018 | 36 | 2018 |
Targeting multiple targets in Pseudomonas aeruginosa PAO1 using flux balance analysis of a reconstructed genome-scale metabolic network D Perumal, A Samal, KR Sakharkar, MK Sakharkar Journal of drug targeting 19 (1), 1-13, 2011 | 35 | 2011 |
Dual targeting of CDK4 and ARK5 using a novel kinase inhibitor ON123300 exerts potent anticancer activity against multiple myeloma D Perumal, PY Kuo, VV Leshchenko, Z Jiang, SKA Divakar, HJ Cho, ... Cancer research 76 (5), 1225-1236, 2016 | 32 | 2016 |
Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas SKA Divakar, R Reddy, SC Cosenza, SJ Baker, D Perumal, AC Antonelli, ... Leukemia 30 (1), 86-93, 2016 | 27 | 2016 |
MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21Cip1 AHC Mei, K Tung, J Han, D Perumal, A Laganą, J Keats, D Auclair, ... Oncotarget 11 (7), 727, 2020 | 16 | 2020 |
Cloning and Targeted Disruption of Two Lipopolysaccharide Biosynthesis Genes, kdsA and waaG, of Pseudomonas aeruginosa PAO1 by Site-Directed … D Perumal, KR Sakharkar, TH Tang, VTK Chow, CS Lim, A Samal, ... Journal of Molecular Microbiology and Biotechnology 19 (4), 169-179, 2011 | 14 | 2011 |
A combined computational-experimental analyses of selected metabolic enzymes in Pseudomonas species D Perumal, CS Lim, VTK Chow, KR Sakharkar, MK Sakharkar International journal of biological sciences 4 (5), 309, 2008 | 13 | 2008 |